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A previously established multiscale population genetics model states that fitness can be inferred from the physical properties of proteins under the physiological assumption that a loss of stability by any protein confers the lethal…

Biomolecules · Quantitative Biology 2009-06-03 Peiqiu Chen , Eugene I. Shakhnovich

In this paper, we discuss remnants of the Bardeen regular black hole motivated by using the concept of thermal fluctuations. First, we derive the equilibrium values of various thermodynamic quantities like entropy, Hawking temperature,…

General Relativity and Quantum Cosmology · Physics 2021-09-14 Yawar H. Khan , Sudhaker Upadhyay , Prince A. Ganai

DNA deformations play crucial roles in many biological processes and material applications. During DNA deformation, DNA structural parameters often exhibit non-trivial and counterintuitive couplings, such as the twist-stretch and…

Biological Physics · Physics 2021-10-08 Chen Zhang , Fujia Tian , Ying Lu , Bing Yuan , Zhi-Jie Tan , Xing-Hua Zhang , Liang Dai

We consider the presence of cosmic string induced density fluctuations in the universe at temperatures below the electroweak phase transition temperature. Resulting temperature fluctuations can restore the electroweak symmetry locally,…

High Energy Physics - Phenomenology · Physics 2009-11-07 Biswanath Layek , Soma Sanyal , Ajit M. Srivastava

The hydrophobic effect stabilizes the native structure of proteins by minimizing the unfavourable interactions between hydrophobic residues and water through the formation of a hydrophobic core. Here we include the entropic and enthalpic…

Soft Condensed Matter · Physics 2016-03-23 Erik van Dijk , Patrick Varilly , Tuomas Knowles , Daan Frenkel , Sanne Abeln

The interplay between quantum and thermal fluctuations in the presence of quenched random disorder is a long-standing open theoretical problem which has been made more urgent by advances in modern experimental techniques. The fragility of…

Strongly Correlated Electrons · Physics 2025-01-28 Matthew C. O'Brien , Eduardo Fradkin

There is an ever-growing need for predictive models for the elasto-viscoplastic deformation of solids. Our goal in this paper is to incorporate recently developed out-of-equilibrium statistical concepts into a thermodynamically consistent,…

Materials Science · Physics 2015-06-18 Ken Kamrin , Eran Bouchbinder

Enhanced dynamical fluctuations of RNAs, facilitated by a network of water molecules with strong interactions with RNA, are suspected to be critical in their ability to respond to a variety of cellular signals. Using atomically detailed…

Biomolecules · Quantitative Biology 2015-01-15 Jeseong Yoon , Jong-Chin Lin , Changbong Hyeon , D. Thirumalai

We investigate the melting transition of non-supercoiled circular DNA of different lengths, employing Brownian dynamics simulation. In the absence of supercoiling, we find that melting of circular DNA is driven by a large bubble, which…

Soft Condensed Matter · Physics 2024-10-14 Souradeep Sengupta , Somendra M. Bhattacharjee , Garima Mishra

When a physical system is put in contact with a very large thermal bath, it undergoes a dissipative (i.e., an apparently irreversible) process that leads to thermal equilibrium. This dynamical process can be described fully within quantum…

Quantum Physics · Physics 2015-05-13 Valerio Scarani

We investigate diffusion-limited reactions between a diffusing particle and a target site on a semiflexible polymer, a key factor determining the kinetics of DNA-protein binding and polymerization of cytoskeletal filaments. Our theory…

Soft Condensed Matter · Physics 2010-12-08 Yann von Hansen , Roland R. Netz , Michael Hinczewski

It is analytically shown that the asymptotic correlations in exactly solvable models following a quantum quench can behave essentially as thermal correlations provided the entanglement between two eigenmodes is sufficiently strong. We…

Statistical Mechanics · Physics 2015-06-04 Ming-Chiang Chung , Anibal Iucci , Miguel. A. Cazalilla

We present a study on the role of defects on the stability of short DNA molecules. We consider short DNA molecules (16 base pairs) and investigate the thermal as well as mechanical denaturation of these molecules in the presence of defects…

Statistical Mechanics · Physics 2015-09-29 Amar Singh , Navin Singh

Hydro-kinetic theory of thermal fluctuations is applied to a non-conformal relativistic fluid. Solving the hydro-kinetic equations for an isotropically expanding background we find that hydrodynamic fluctuations give ultraviolet divergent…

Nuclear Theory · Physics 2018-08-21 Yukinao Akamatsu , Aleksas Mazeliauskas , Derek Teaney

Understanding how soft matter systems, including biological ones, can develop collective electromagnetic phenomena under external fields at ambient conditions remains a central challenge, as thermal fluctuations are generally expected to…

Biological Physics · Physics 2026-01-21 Mariusz Pietruszka

Thermal fluctuations constantly and evenly excite all vibrational modes in an equilibrium crystal. As the temperature rises, these fluctuations promote the formation of defects and eventually melting. In active solids, the self-propulsion…

Soft Condensed Matter · Physics 2024-09-25 Helena Massana-Cid , Claudio Maggi , Nicoletta Gnan , Giacomo Frangipane , Roberto Di Leonardo

Thermal rectification and negative differential thermal resistance are two important features that have direct technological relevance. In this paper, we study the classical one dimensional Heisenberg model, thermally driven by heat baths…

Statistical Mechanics · Physics 2015-06-23 Debarshee Bagchi

A general theory of thermal magnetic fluctuations near conductive materials is developed; such fluctuations are the magnetic analog of Johnson noise. For realistic experiments in quantum computing and magnetic resonance force microscopy,…

Quantum Physics · Physics 2007-05-23 J. A. Sidles , J. L. Garbini , W. M. Dougherty , S. H. Chao

The responses of a $1+\epsilon $ dimensional directed path to temperature and to potential variations are calculated exactly, and are governed by the same scaling form. The short scale decorrelation (strong correlation regime) leads to the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Rava A. da Silveira , Jean-Philippe Bouchaud

A theory is presented of the longitudinal dispersion of DNA under equilibrium confined in a nanochannel. Orientational fluctuations of the DNA chain build up to give rise to substantial fluctuations of the coil in the longitudinal direction…

Soft Condensed Matter · Physics 2009-11-18 Theo Odijk
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