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Periodic arrays of micro- or nano-pillars constitute solid state matrices with excellent properties for DNA size separation. Nanofabrication technologies offer many solutions to tailor the geometry of obstacle arrays, yet most studies have…

Biological Physics · Physics 2014-09-02 Yannick Viero , Qihao He , Marc Fouet , Aurélien Bancaud

We present results of an ultraviolet photoemission spectroscopy study of artificially synthesized poly(dA)-poly(dT) DNA molecules on $p$-type Si substrates. For comparison, we also present the electronic density of states (DOS) calculated…

Soft Condensed Matter · Physics 2007-05-23 Hiroki Wadati , Kozo Okazaki , Yasuhiro Niimi , Atsushi Fujimori , Hitoshi Tabata , Jared Pikus , James P. Lewis

In living cells, proteins combine 3D bulk diffusion and 1D sliding along the DNA to reach a target faster. This process is known as facilitated diffusion, and we investigate its dynamics in the physiologically relevant case of confined DNA.…

Soft Condensed Matter · Physics 2015-06-12 G. Foffano , D. Marenduzzo , E. Orlandini

In this work we investigate the electronic transport along model DNA molecules using an effective tight-binding approach that includes the backbone on site energies. The localization length and participation number are examined as a…

Mesoscale and Nanoscale Physics · Physics 2015-06-11 C. J. Páez , P. A. Schulz

We introduce a coarse-grained model of DNA with bases modeled as rigid-body ellipsoids to capture their anisotropic stereochemistry. Interaction potentials are all physicochemical and generated from all-atom simulation/parameterization with…

Soft Condensed Matter · Physics 2015-05-14 Alex Morriss-Andrews , Joerg Rottler , Steven S. Plotkin

A double-stranded DNA unravels thermally through intermediate denatured bubble segments. Intrinsically, fluctuations ensue at the bubble boundaries from non-equilibrium (NE) energy exchanges with the environment. However, such details gets…

Soft Condensed Matter · Physics 2018-09-21 Keren Jiang , Faheem Khan , Javix Thomas , Arindam Phani , Thomas Thundat

The electronic structure of an infinite poly-guanine - poly-cytosine DNA molecule in its dry A-helix structure is studied by means of density-functional calculations. An extensive study of 30 nucleic base pairs is performed to validate the…

Soft Condensed Matter · Physics 2009-11-07 E. Artacho , M. Machado , D. Sanchez-Portal , P. Ordejon , J. M. Soler

We derive formulae for the electrostatic interaction between two long, rigid macromolecules that may have arbitrary surface charge patterns and cross at an arbitrary interaxial angle. We calculate the dependence of the interaction energy on…

Soft Condensed Matter · Physics 2009-10-31 A. A. Kornyshev , S. Leikin

Ferroelectric domain nucleation and growth in multiferroic BiFeO3 films is observed directly by applying a local electric field with a conductive tip inside a scanning transmission electron microscope. The nucleation and growth of a…

We discuss the thermodynamic behaviour near the force induced unzipping transition of a double stranded DNA in two different ensembles. The Y-fork is identified as the coexisting phases in the fixed distance ensemble. From finite size…

Soft Condensed Matter · Physics 2007-05-23 Rajeev Kapri , Somendra M. Bhattacharjee

The electrical properties of DNA molecules are investigated by charge injection and electric force microscopy experiments. Prior to injection, DNA molecules exhibit a weak positively charged state. We probe the electrical behaviour of DNA…

Materials Science · Physics 2009-11-10 Thomas Heim , Thierry Melin , Dominique Deresmes , Dominique Vuillaume

Photo-induced charge separation in nanowires or molecular wires had been studied in previous experiments and simulations. Most researches deal with the carrier diffusions with the classical phenomenological models, or the static energy…

Mesoscale and Nanoscale Physics · Physics 2018-04-13 Hang Xie , Yu Zhang , Yanho Kwok , Wei E. I. Sha

A novel bio-photonics approach based on the nonlinear optical process of second harmonic generation by non-centrosymmetric nanoparticles is presented and demonstrated on malignant human cell lines. The proposed method allows to directly…

Samples suitable for electron diffraction studies must satisfy certain characteristics such as having a thickness in the range of 10 - 100 nm. We report, to our knowledge, the first successful synthesis technique of nanometer-thin sheets of…

Chemical Physics · Physics 2024-01-17 Hazem Daoud , Sreelaja Pulleri Vadhyar , Ehsan Nikbin , Cheng Lu , R. J. Dwayne Miller

We present a variation of two-dimensional electronic spectroscopy that is capable of mapping spatially-varying differences in electronic couplings using a correlated map of excitation and detection frequencies, with sensitivity orders of…

The temperature dependence of DNA flexibility is studied in the presence of stretching and unzipping forces. Two classes of models are considered. In one case the origin of elasticity is entropic due to the polymeric correlations, and in…

Soft Condensed Matter · Physics 2016-06-27 Tanmoy Pal , Somendra M. Bhattacharjee

Short blunt-ended DNA duplexes comprising 6 to 20 base pairs self-assemble into polydisperse semi-flexible chains due to hydrophobic stacking interactions between terminal base pairs. Above a critical concentration, which depends on…

Soft Condensed Matter · Physics 2012-07-17 Cristiano De Michele , Lorenzo Rovigatti , Tommaso Bellini , Francesco Sciortino

The experiment that the high spin selectivity and the length-dependent spin polarization are observed in double-stranded DNA [Science ${\bf 331}$, 894 (2011)], is elucidated by considering the combination of the spin-orbit coupling, the…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Ai-Min Guo , Qing-feng Sun

We introduce a coarse-grained rigid nucleotide model of DNA that reproduces the basic thermodynamics of short strands: duplex hybridization, single-stranded stacking and hairpin formation, and also captures the essential structural…

Soft Condensed Matter · Physics 2010-05-14 Thomas E. Ouldridge , Ard A. Louis , Jonathan P. K. Doye

Recent theoretical predictions on DNA mechanical separation induced by pulling forces are numerically tested within a model in which self-avoidance for DNA strands is fully taken into account. DNA strands are described by interacting pairs…

Statistical Mechanics · Physics 2009-11-07 Enzo Orlandini , Somendra M. Bhattacharjee , Davide Marenduzzo , Amos Maritan , Flavio Seno