English

Frequency Doubling Nanocrystals for Cancer Theranostics

Biological Physics 2015-11-11 v1 Medical Physics Optics

Abstract

A novel bio-photonics approach based on the nonlinear optical process of second harmonic generation by non-centrosymmetric nanoparticles is presented and demonstrated on malignant human cell lines. The proposed method allows to directly interact with DNA in absence of photosensitizing molecules, to enable independent imaging and therapeutic modalities switching between the two modes of operation by simply tuning the excitation laser wavelength, and to avoid any risk of spontaneous activation by any natural or artificial light source.

Keywords

Cite

@article{arxiv.1306.6487,
  title  = {Frequency Doubling Nanocrystals for Cancer Theranostics},
  author = {Davide Staedler and Thibaud Magouroux and Solène Passemard and Sebastian Schwung and Marc Dubled and Guillaume Stéphane Schneiter and Daniel Rytz and Sandrine Gerber-Lemaire and Luigi Bonacina and Jean-Pierre Wolf},
  journal= {arXiv preprint arXiv:1306.6487},
  year   = {2015}
}

Comments

16 pages, 7 figures

R2 v1 2026-06-22T00:41:23.261Z