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The dynamics of red blood cells (RBCs) in simple shear flow was studied using a theoretical approach based on three variables: a shape parameter, the inclination angle $\theta$, and phase angle $\phi$ of the membrane rotation. At high shear…

Soft Condensed Matter · Physics 2009-08-07 Hiroshi Noguchi

Cell dynamics simulation is used to investigate the phase behavior of block copolymer/homopolymer mixture subjected to a steady shear flow. Phase transitions occur from transverse to parallel and then to perpendicular lamellar structure…

Soft Condensed Matter · Physics 2015-06-29 Y. Guo , J. Zhang , B. Wang , H. Wu , M. Sun , J. Pan

Using fundamental-measure density functional theory we investigate entropic wetting in an asymmetric binary mixture of hard spheres with positive non-additivity. We consider a general planar hard wall, where preferential adsorption is…

Soft Condensed Matter · Physics 2015-05-28 Paul Hopkins , Matthias Schmidt

We study a simple model of shear banding in which the flow-induced phase is destabilised by coupling between flow and microstructure (wormlike micellar length). By varying the strength of the instability and the applied shear rate, we find…

Soft Condensed Matter · Physics 2007-05-23 Suzanne Fielding , Peter Olmsted

We image the flow of a nearly random close packed, hard-sphere colloidal suspension (a `paste') in a square capillary using confocal microscopy. The flow consists of a `plug' in the center while shear occurs localized adjacent to the…

Soft Condensed Matter · Physics 2009-11-13 Lucio Isa , Rut Besseling , Wilson C K Poon

Red blood cells (RBCs) are responsible for transporting oxygen and various metabolites to tissues and organs, as well as removing waste. Several cardiovascular diseases can impair these functions. For instance, in diabetes, increased RBC…

Biological Physics · Physics 2025-01-08 Mehdi Abbasi , Chaouqi Misbah

Through high-fidelity numerical simulation, the simple shear flow over regularly arranged micro pillars has been investigated. The essential issues to be addressed include the characteristics of a simple shear flow over quadrilateral array…

Fluid Dynamics · Physics 2022-03-14 Yanxing Wang , Hui Wan , Tie Wei , Fangjun Shu

We discuss the advantages and results of using a mixing-length, compressible model to account for shear banding behaviour in granular flow. We formulate a general approach based on two function of the solid fraction to be determined.…

Soft Condensed Matter · Physics 2009-11-13 Riccardo Artoni , Andrea Santomaso , Paolo Canu

The wall shear rate distribution P(gamma) is investigated for pressure-driven Stokes flow through random arrangements of spheres at packing fractions 0.1 <= phi <= 0.64. For dense packings, P(gamma) is monotonic and approximately…

Soft Condensed Matter · Physics 2009-11-13 Patrick B. Warren , Frantisek Stepanek

Multivalent particles competing for binding on the same surface can exhibit switch-like behaviour, depending on the concentration of receptors on the surface. When the receptor concentration is low, energy dominates the free energy of…

Soft Condensed Matter · Physics 2016-08-24 Nicholas B. Tito , Daan Frenkel

Vascular adhesion of circulating tumor cells (CTCs) is a key step in cancer spreading. If inflammation is recognized to favor the formation of vascular metastatic niches, little is known about the contribution of blood rheology to CTC…

Blood flow in sickle cell disease (SCD) can substantially differ from normal blood flow due to significant alterations in the physical properties of the red blood cells (RBCs). Chronic complications, such as inflammation of the endothelial…

Biological Physics · Physics 2020-05-13 Xiao Zhang , Christina Caruso , Wilbur A. Lam , Michael D. Graham

Using a micro particle imaging velocity technique, we resolve for the first time the three dimensionnal structure of wormlike shear banding flows in straight microchannels. The study revealed two effects, which should be generic for shear…

Soft Condensed Matter · Physics 2009-09-08 P. Nghe , S. M. Fielding , P. Tabeling , A. Ajdari

Using a density functional based interface displacement model we determine the effective interaction potential between two spherical particles which are immersed in a homogeneous fluid such as the vapor phase of a one-component substance or…

Soft Condensed Matter · Physics 2009-10-31 C. Bauer , T. Bieker , S. Dietrich

We consider the effective surface motion of a particle that freely diffuses in the bulk and intermittently binds to that surface. From an exact approach we derive various regimes of the effective surface motion characterized by physical…

Statistical Mechanics · Physics 2015-05-13 Aleksei V. Chechkin , Irwin M. Zaid , Michael A. Lomholt , Igor M. Sokolov , Ralf Metzler

We present a stochastic model which describes fronts of cells invading a wound. In the model cells can move, proliferate, and experience cell-cell adhesion. We find several qualitatively different regimes of front motion and analyze the…

Cell Behavior · Quantitative Biology 2009-11-13 Evgeniy Khain , Leonard M. Sander , Casey M. Schneider-Mizell

Cells, other than their biological properties, have different electric and physical properties. In an impedance cytometer, cells should pass one by one in the detection region where pairs of electrodes are located. When cells are located…

Signal Processing · Electrical Eng. & Systems 2022-03-09 Hassan Raji , Iraj Dehghan Hamani

Flowing blood displays a phenomenon called margination, in which leukocytes and platelets are preferentially found near blood vessel walls, while erythrocytes are depleted from these regions. Here margination is investigated using direct…

Soft Condensed Matter · Physics 2012-09-05 Amit Kumar , Michael D. Graham

We reveal that under moderate shear stress (of the order of 0.1 Pa) red blood cells present an oscillation of their inclination (swinging) superimposed to the long-observed steady tanktreading (TT) motion. A model based on a fluid ellipsoid…

Biological Physics · Physics 2009-11-13 Manouk Abkarian , Magalie Faivre , Annie Viallat

We report experiments on slow granular flows in a split-bottom Couette cell that show novel strain localization features. Nontrivial flow profiles have been observed which are shown to be the consequence of simultaneous formation of shear…

Soft Condensed Matter · Physics 2013-10-08 Robabeh Moosavi , M. Reza Shaebani , Maniya Maleki , Janos Torok , Dietrich E. Wolf , Wolfgang Losert