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The transport of motile entities across modulated energy landscapes plays an important role in a range of phenomena in biology, colloidal science and solid-state physics. Here, an easily implementable strategy that allows for the collective…

Soft Condensed Matter · Physics 2020-03-11 Fernando Martínez-Pedrero , Francisco Ortega , Ramón G. Rubio , Carles Calero

Biomolecular condensates self-assemble when proteins and nucleic acids spontaneously demix to form droplets within the crowded intracellular milieu. This simple mechanism underlies the formation of a wide variety of membraneless…

Statistical Mechanics · Physics 2021-06-30 William M. Jacobs

Bacteria can adjust the structure of colonies and biofilms to enhance their survival rate under external stress. Here, we explore the link between bacterial interaction forces and colony structure. We show that the activity of extracellular…

We investigate the cooperative dynamics of an ensemble of N microtubules growing against an elastic barrier. Microtubules undergo so-called catastrophes, which are abrupt stochastic transitions from a growing to a shrinking state, and…

Subcellular Processes · Quantitative Biology 2013-01-08 Björn Zelinski , Jan Kierfeld

Nonlinear wave propagation plays a crucial role in the functioning of many physical and biophysical systems. In the propagation regime, disturbances due to the presence of local external perturbations, such as localised defects or boundary…

Pattern Formation and Solitons · Physics 2018-11-20 Juan F. Marín

Microtubule dynamic instability arises from the hydrolysis of GTP bound to the beta-monomer of the tubulin dimer. The conformational change induced by hydrolysis is unknown, but microtubules disassemble into protofilaments of GDP-bound…

Biological Physics · Physics 2007-05-23 Deborah Kuchnir Fygenson

Inside cells, various cargos are transported by teams of molecular motors. Intriguingly, the motors involved generally have opposite pulling directions, and the resulting cargo dynamics is a biased stochastic motion. It is an open question…

Biological Physics · Physics 2017-09-20 Sarah Klein , Cécile Appert-Rolland , Ludger Santen

Perturbations of fluid media can give rise to non-equilibrium dynamics, which may in turn cause motion of immersed inclusions. We consider perturbations ("activations") that are local in space and time, of a fluid density which is…

Statistical Mechanics · Physics 2020-03-18 Christian M. Rohwer , Mehran Kardar , Matthias Krüger

The counterintuitive emergence of order from noise is a central phenomenon in science, ranging from pattern formation and synchronization to order-by-disorder in frustrated systems. While large-scale spatial self-organization induced by…

Soft Condensed Matter · Physics 2026-02-02 Satyam Anand , Guanming Zhang , Stefano Martiniani

The growth of interfacial instabilities during fluid displacements can be driven by gradients in pressure, viscosity and surface tension, and by applying external fields. Since displacements of non-Newtonian fluids such as polymer…

Soft Condensed Matter · Physics 2024-07-02 Vaibhav Raj Singh Parmar , Ranjini Bandyopadhyay

Dynamic instability of microtubules is considered using frameworks of non-linear thermodynamics and non-equilibrium reaction-diffusion systems. Stochastic assembly/disassembly phases in the polymerization dynamics of microtubules are…

Subcellular Processes · Quantitative Biology 2016-11-15 Eugene Katrukha

We analyze the isotropic compaction of assemblies composed of soft pentagons interacting through classical Coulomb friction via numerical simulations. The effect of the initial particle shape is discussed by comparing packings of pentagons…

Soft Condensed Matter · Physics 2021-06-16 Manuel Cárdenas-Barrantes , David Cantor , Jonathan Barés , Mathieu Renouf , Emilien Azéma

We study a reaction-diffusion model posed on two distinct spatial scales that accounts for diffusion, aggregation, fragmentation, and deposition of populations of colloidal particles within a porous material. In this model, the macroscopic…

Analysis of PDEs · Mathematics 2026-04-14 Christos Nikolopoulos , Michael Eden , Adrian Muntean

Obstructions influence the growth and expansion of bodies in a wide range of settings -- but isolating and understanding their impact can be difficult in complex environments. Here, we study obstructed growth/expansion in a model system…

Soft Condensed Matter · Physics 2024-01-24 Abigail Plummer , Caroline Adkins , Jean-François Louf , Andrej Košmrlj , Sujit S. Datta

Inspired by recent experimental observation of patterning at the membrane of a living cell, we propose a generic model for the dynamics of a fluctuating interface driven by particle-like inclusions which stimulate its growth. We find that…

Soft Condensed Matter · Physics 2019-07-25 F. Cagnetta , M. R. Evans , D. Marenduzzo

Swimming cells and microorganisms must often move though complex fluids that contain an immersed microstructure such as polymer molecules, or filaments. In many important biological processes, such as mammalian reproduction and bacterial…

Fluid Dynamics · Physics 2018-08-06 Arshad Kamal , Eric E Keaveny

Faithful segregation of genetic material during cell division requires alignment of chromosomes between two spindle poles and attachment of their kinetochores to each of the poles. Failure of these complex dynamical processes leads to…

Biological Physics · Physics 2015-12-08 Zsolt Bertalan , Zoe Budrikis , Caterina A. M. La Porta , Stefano Zapperi

Biological transport networks adapt through dynamic interactions between material transport and structural modification during growth and development. In this work, we present a model of transport network growth driven by local material…

Biological Physics · Physics 2025-03-27 Chanoknun Sintavanuruk , Yoichiro Mori , Reza Farhadifar , Eleni Katifori

Microtubules are a major component of the cytoskeleton distinguished by highly dynamic behavior both in vitro and in vivo. We propose a general mathematical model that accounts for the growth, catastrophe, rescue and nucleation processes in…

Biological Physics · Physics 2015-05-13 Peter Hinow , Vahid Rezania , Jack A. Tuszynski

We extend the notions of multipole and subsystem symmetries to more general {\it spatially modulated} symmetries. We uncover two instances with exponential and (quasi)-periodic modulations, and provide simple microscopic models in one, two…

Statistical Mechanics · Physics 2021-10-19 Pablo Sala , Julius Lehmann , Tibor Rakovszky , Frank Pollmann
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