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Confining surfaces play crucial roles in dynamics, transport and order in many physical systems, but their effects on active matter, a broad class of dynamically self-organizing systems, are poorly understood. We investigate here the…

Soft Condensed Matter · Physics 2013-07-23 Hugo Wioland , Francis G. Woodhouse , Jörn Dunkel , John O. Kessler , Raymond E. Goldstein

The synaptic connectivity of cortical networks features an overrepresentation of certain wiring motifs compared to simple random-network models. This structure is shaped, in part, by synaptic plasticity that promotes or suppresses…

Neurons and Cognition · Quantitative Biology 2014-12-23 Gabriel Koch Ocker , Ashok Litwin-Kumar , Brent Doiron

The vortex dynamics in a low temperature superconductor deposited on top of a rectangular array of micrometer size permalloy triangles is investigated experimentally. The rectangular unit cell is such that neighboring triangles physically…

Superconductivity · Physics 2009-11-13 J. Van de Vondel , A. V. Silhanek , V. Metlushko , P. Vavassori , B. Ilic , V. V. Moshchalkov

Recent research has provided a wealth of evidence highlighting the pivotal role of high-order interdependencies in supporting the information-processing capabilities of distributed complex systems. These findings may suggest that high-order…

Adaptation and Self-Organizing Systems · Physics 2023-05-24 Patricio Orio , Pedro A. M. Mediano , Fernando E. Rosas

A novel theoretical model of dynamic instability of a system of linear (1D) microtubules (MTs) in a bounded domain is introduced for studying the role of a cell edge in vivo and analyzing the effect of competition for a limited amount of…

Subcellular Processes · Quantitative Biology 2007-05-23 Gennady Margolin , Ivan V. Gregoretti , Holly V. Goodson , Mark S. Alber

We consider collective dynamics of self-propelling particles in two dimensions. They can align themselves according to the direction of propulsion of their neighbours, together with a random perturbation (i.e. rotational fluctuation). They…

Soft Condensed Matter · Physics 2019-04-01 Shubhashis Rana , Md. Samsuzzaman , Arnab Saha

Natural porous systems, such as soil, membranes, and biological tissues comprise disordered structures characterized by dead-end pores connected to a network of percolating channels. The release and dispersion of particles, solutes, and…

We model and study the patterns created through the interaction of collectively moving self-propelled particles (SPPs) and elastically tethered obstacles. Simulations of an individual-based model reveal at least three distinct large-scale…

Microtubules and motor proteins are building blocks of self-organized subcellular biological structures such as the mitotic spindle and the centrosomal microtubule array. These same ingredients can form new "bioactive" liquid-crystalline…

Soft Condensed Matter · Physics 2015-01-29 Tong Gao , Robert Blackwell , Matthew A. Glaser , M. D. Betterton , Michael J. Shelley

By analytically solving some simple models of phase-ordering kinetics, we suggest a mechanism for the onset of non-equilibrium behaviour in colloid-polymer mixtures. These mixtures can function as models of atomic systems; their physics…

Soft Condensed Matter · Physics 2016-08-31 R. M. L. Evans , W. C. K. Poon

We report three-dimensional particle mechanics static calculations that predict the microstructure evolution during die-compaction of elastic spherical particles up to relative densities close to one. We employ a nonlocal contact…

Soft Condensed Matter · Physics 2016-08-03 Marcial Gonzalez , Alberto M. Cuitino

We model the effects of confinement on the stable self-organized patterns obtained in the non-equilibrium steady states of mixtures of molecular motors and microtubules. In experiments [Nedelec et al. Nature, 389, 305 (1997); Surrey et al.,…

Statistical Mechanics · Physics 2007-05-23 Sumithra Sankararaman , Gautam I. Menon , P. B. Sunil Kumar

A simple phenomenological model for describing the conformational dynamics of biological macromolecules via the nonlinearity-induced instabilities is proposed. It is shown that the interaction between charges and bending degrees of freedom…

Soft Condensed Matter · Physics 2009-11-11 Yu. B. Gaididei , P. L. Christiansen , W. J. Zakrzewski

Microtubules and motor proteins self organize into biologically important assemblies including the mitotic spindle and the centrosomal microtubule array. Outside of cells, microtubule-motor mixtures can form novel active liquid-crystalline…

Soft Condensed Matter · Physics 2016-01-20 Tong Gao , Robert Blackwell , Matthew A. Glaser , M. D. Betterton , Michael J. Shelley

We study a one-dimensional model of microtubule assembly/disassembly in which GTP bound to tubulins within the microtubule undergoes stochastic hydrolysis. In contrast to models that only consider a cap of GTP-bound tubulin, stochastic…

Biomolecules · Quantitative Biology 2015-05-13 Sumedha , Michael F Hagan , Bulbul Chakraborty

The central task in the study of self-organization is to explore the general mechanism of emergences. However, this is inhibited by the missing of a full knowledge of the microscopic dynamics of emergence. Here, in this study, the…

Soft Condensed Matter · Physics 2022-04-21 Yang Yang , Zhi Chao Zhang , Fei Qi , Tian Hui Zhang

Spatial organisation is a hallmark of all living cells, and recreating it in model systems is a necessary step in the creation of synthetic cells. It is therefore of both fundamental and practical interest to better understand the basic…

Biological Physics · Physics 2017-12-19 Jaime Agudo-Canalejo , Ramin Golestanian

Mechanical interactions among cells in a growing microbial colony can significantly influence the colony's spatial genetic structure and, thus, evolutionary outcomes such as the fates of rare mutations. Here, we computationally investigate…

Soft Condensed Matter · Physics 2025-01-22 Mateusz Ratman , Jimmy Gonzalez Nuñez , Daniel A. Beller

One of the most interesting phenomena in the soft-matter realm consists in the spontaneous formation of super-molecular structures (microphases) in condition of thermodynamic equilibrium. A simple mechanism responsible for this…

Soft Condensed Matter · Physics 2017-08-23 A. Imperio , D. Pini , L. Reatto

In this paper we address some modelling issues related to biological growth. Our treatment is based on a recently-proposed, general formulation for growth within the context of Mixture Theory (Journal of the Mechanics and Physics of Solids,…

Tissues and Organs · Quantitative Biology 2011-11-09 H. Narayanan , E. M. Arruda , K. Grosh , K. Garikipati
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