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Intracellular cargo transport can arise from passive diffusion, active motor-driven transport along cytoskeletal filament networks, and passive advection by fluid flows entrained by such motor/cargo motion. Active and advective transport…

Biological Physics · Physics 2012-07-24 P. Khuc Trong , J. Guck , R. E. Goldstein

This paper focuses on the affective component of a driver behavioural model (DBM). This component specifically models some drivers' mental states such as mental load and active fatigue, which may affect driving performance. We have used…

Experiments suggest that the migration of some cells in the three-dimensional extra cellular matrix bears strong resemblance to one-dimensional cell migration. Motivated by this observation, we construct and study a minimal one-dimensional…

Soft Condensed Matter · Physics 2015-06-22 J. H. Lopez , Moumita Das , J. M. Schwarz

Intracellular transport is an essential function in eucaryotic cells, facilitated by motor proteins - proteins converting chemical energy into kinetic energy. It is known that motor proteins work in teams enabling unidirectional and…

Subcellular Processes · Quantitative Biology 2016-03-29 Shreyas Bhaban , Donatello Materassi , Mingang Li , Thomas Hays , Murti Salapaka

Biopolymers serve as one-dimensional tracks on which motor proteins move to perform their biological roles. Motor protein phenomena have inspired theoretical models of one-dimensional transport, crowding, and jamming. Experiments studying…

Biological Physics · Physics 2016-05-25 Hui-Shun Kuan , M. D. Betterton

We study the mechanical and thermodynamic properties of different traffic models for kinesin which are relevant in biological and experimental contexts. We find that motor-motor interactions play a fundamental role by enhancing the…

Statistical Mechanics · Physics 2013-07-18 Natalia Golubeva , Alberto Imparato

Linear bio-molecular motors move unidirectionally along a track by coordinating several different processes, such as fuel (ATP) capture, hydrolysis, conformational changes, binding and unbinding from a track, and center-of-mass diffusion. A…

Statistical Mechanics · Physics 2015-05-18 Nathan J. Kuwada , Gerhard A. Blab , Heiner Linke

Because of its nonequilibrium character, active matter in a steady state can drive engines that autonomously deliver work against a constant mechanical force or torque. As a generic model for such an engine, we consider systems that contain…

Statistical Mechanics · Physics 2019-11-15 Patrick Pietzonka , Étienne Fodor , Christoph Lohrmann , Michael E. Cates , Udo Seifert

The effect of sequence heterogeneity on the dynamics of molecular motors is reviewed and analyzed using a set of recently introduced lattice models. First, we review results for the influence of heterogenous tracks such as a single-strand…

Statistical Mechanics · Physics 2015-06-25 Yariv Kafri , David R. Nelson

In cellular automata with memory, the unchanged maps of the conventional cellular automata are applied to cells endowed with memory of their past states in some specified interval. We implement Rule 30 automata with a majority memory and…

Cellular Automata and Lattice Gases · Physics 2010-11-23 Genaro J. Martinez , Andrew Adamatzky , Ramon Alonso-Sanz , J. C. Seck-Touh-Mora

Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…

Soft Condensed Matter · Physics 2025-05-26 Fan Yang , Shichen Liu , Heun Jin Lee , Rob Phillips , Matt Thomson

In this work we extend a recent kinetic traffic model to the case of more than one class of vehicles, each of which is characterized by few different microscopic features. We consider a Boltzmann-like framework with only binary…

Numerical Analysis · Mathematics 2017-02-22 Gabriella Puppo , Matteo Semplice , Andrea Tosin , Giuseppe Visconti

This paper focuses on the affective component of a Driver Behavioural Model (DBM), specifically modelling some driver's mental states, such as mental load and active fatigue, which may affect driving performance. We used Bayesian networks…

A two-dimensional cellular automaton is introduced to model the flow and jamming of vehicular traffic in cities. Each site of the automaton represents a crossing where a finite number of cars can wait approaching the crossing from each of…

Statistical Mechanics · Physics 2015-06-24 Jan Freund , Thorsten Poeschel

The ability of many living systems to actively self-propel underlies critical biomedical, environmental, and industrial processes. While such active transport is well-studied in uniform settings, environmental complexities such as geometric…

Biological Physics · Physics 2021-08-23 Alejandro Martínez-Calvo , Carolina Trenado-Yuste , Sujit S. Datta

A two--dimensional cellular automaton is introduced to model the flow and jamming of vehicular traffic in cities. Each site of the automaton represents a crossing where a finite number of cars can wait approaching the crossing from each of…

adap-org · Physics 2008-02-03 Jan Freund , Thorsten Pöschel

We introduce a multi-species lattice gas model for motor protein driven collective cargo transport on cellular filaments. We use this model to describe and analyze the collective motion of interacting vesicle cargoes being carried by…

Statistical Mechanics · Physics 2010-09-10 Sudipto Muhuri , Ignacio Pagonabarraga

We model and simulate the stepping dynamics of the kinesin motor including electric and mechanical forces, environmental noise, and the complicated potentials produced by tracking and neighboring protofilaments. Our dynamical model supports…

Biological Physics · Physics 2016-05-02 Alexander I Nesterov , Gennady P Berman , Mónica F Ramírez

Diffusion of transported particles in the intracellular medium is described by means of a generalized diffusion equation containing forces due to the cytoskeleton network and to the protein motors. We find that the enhanced diffusion…

Soft Condensed Matter · Physics 2009-02-05 I. Santamaria-Holek , M. H. Vainstein , J. M. Rubi , F. A. Oliveira

Inside cells, cargos such as vesicles and organelles are transported by molecular motors to their correct locations via active motion on cytoskeletal tracks and passive, Brownian diffusion. During the transportation of cargos, motor-cargo…

Soft Condensed Matter · Physics 2018-04-10 Supravat Dey , Kevin Ching , Moumita Das