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Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

Molecular Networks · Quantitative Biology 2023-02-06 Larry Bull

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. The topologies of random Boolean networks with one input per…

Disordered Systems and Neural Networks · Physics 2009-11-11 Björn Samuelsson , Carl Troein

Random Boolean networks (RBNs) are models of genetic regulatory networks. It is useful to describe RBNs as self-organizing systems to study how changes in the nodes and connections affect the global network dynamics. This article reviews…

Adaptation and Self-Organizing Systems · Physics 2010-09-24 Carlos Gershenson

We provide the first classification of different types of Random Boolean Networks (RBNs). We study the differences of RBNs depending on the degree of synchronicity and determinism of their updating scheme. For doing so, we first define…

Computational Complexity · Computer Science 2007-05-23 Carlos Gershenson

Genetic regulatory networks control ontogeny. For fifty years Boolean networks have served as models of such systems, ranging from ensembles of random Boolean networks as models for generic properties of gene regulation to working dynamical…

Molecular Networks · Quantitative Biology 2019-02-04 Stefan Bornholdt , Stuart Kauffman

We study a dynamical random network model in which at every construction step a new vertex is introduced and attached to every existing vertex independently with a probability proportional to a concave function f of its current degree. We…

Probability · Mathematics 2013-02-06 Steffen Dereich , Peter Mörters

The evaluation of the number of attractors in Kauffman networks by Samuelsson and Troein is generalized to critical networks with one input per node and to networks with two inputs per node and different probability distributions for update…

Statistical Mechanics · Physics 2009-11-11 Barbara Drossel

We investigate Threshold Random Boolean Networks with $K = 2$ inputs per node, which are equivalent to Kauffman networks, with only part of the canalyzing functions as update functions. According to the simplest consideration these networks…

Disordered Systems and Neural Networks · Physics 2007-07-16 Florian Greil , Barbara Drossel

We study two measures of the complexity of heterogeneous extended systems, taking random Boolean networks as prototypical cases. A measure defined by Shalizi et al. for cellular automata, based on a criterion for optimal statistical…

Cellular Automata and Lattice Gases · Physics 2012-06-12 Xinwei Gong , Joshua E. S. Socolar

In this work, several random Boolean networks (RBN) are generated and analyzed from two characteristics: their time evolution diagram and their transition diagram. For this purpose, its randomness is estimated using three measures, of which…

Information Theory · Computer Science 2024-09-04 Manuel de J. Luevano , Alejandro Puga

The complex dynamics of gene expression in living cells can be well-approximated using Boolean networks. The average sensitivity is a natural measure of stability in these systems: values below one indicate typically stable dynamics…

Molecular Networks · Quantitative Biology 2018-10-03 Bryan C. Daniels , Hyunju Kim , Douglas Moore , Siyu Zhou , Harrison Smith , Bradley Karas , Stuart A. Kauffman , Sara I. Walker

We present and discuss the results of an experimental analysis in the design of Boolean networks by means of genetic algorithms. A population of networks is evolved with the aim of finding a network such that the attractor it reaches is of…

Neural and Evolutionary Computing · Computer Science 2011-02-01 Andrea Roli , Cristian Arcaroli , Marco Lazzarini , Stefano Benedettini

The goal of this tutorial is to promote interest in the study of random Boolean networks (RBNs). These can be very interesting models, since one does not have to assume any functionality or particular connectivity of the networks to study…

Adaptation and Self-Organizing Systems · Physics 2009-09-29 Carlos Gershenson

The Kauffman model describes a system of randomly connected nodes with dynamics based on Boolean update functions. Though it is a simple model, it exhibits very complex behavior for "critical" parameter values at the boundary between a…

Disordered Systems and Neural Networks · Physics 2007-05-23 Barbara Drossel , Tamara Mihaljev , Florian Greil

The Kauffman model describes a particularly simple class of random Boolean networks. Despite the simplicity of the model, it exhibits complex behavior and has been suggested as a model for real world network problems. We introduce a novel…

Disordered Systems and Neural Networks · Physics 2007-05-23 B. Samuelsson , C. Troein

Boolean threshold networks have recently been proposed as useful tools to model the dynamics of genetic regulatory networks, and have been successfully applied to describe the cell cycles of \textit{S. cerevisiae} and \textit{S. pombe}.…

Chaotic Dynamics · Physics 2010-11-18 Jorge G. T. Zañudo , Maximino Aldana , Gustavo Martínez-Mekler

We describe systems using Kauffman and similar networks. They are directed funct ioning networks consisting of finite number of nodes with finite number of discr ete states evaluated in synchronous mode of discrete time. In this paper we…

Disordered Systems and Neural Networks · Physics 2009-11-13 Andrzej Gecow

Characterization of the differences between biological and random networks can reveal the design principles that enable the robust realization of crucial biological functions including the establishment of different cell types. Previous…

Molecular Networks · Quantitative Biology 2020-08-26 Shubham Tripathi , David A. Kessler , Herbert Levine

In this paper we study the phase transitions of different types of Random Boolean networks. These differ in their updating scheme: synchronous, semi-synchronous, or asynchronous, and deterministic or non-deterministic. It has been shown…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Carlos Gershenson

Most models of complex systems have been homogeneous, i.e., all elements have the same properties (spatial, temporal, structural, functional). However, most natural systems are heterogeneous: few elements are more relevant, larger,…

Adaptation and Self-Organizing Systems · Physics 2025-12-22 Amahury Jafet López-Díaz , Fernanda Sánchez-Puig , Carlos Gershenson