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Boolean networks with canalizing functions are used to model gene regulatory networks. In order to learn how such networks may behave under evolutionary forces, we simulate the evolution of a single Boolean network by means of an adaptive…

Populations and Evolution · Quantitative Biology 2011-11-09 Agnes Szejka , Barbara Drossel

The concept of control is crucial for effectively understanding and applying biological network models. Key structural features relate to control functions through gene regulation, signaling, or metabolic mechanisms, and computational…

Molecular Networks · Quantitative Biology 2024-11-05 David Murrugarra , Alan Veliz-Cuba , Elena Dimitrova , Claus Kadelka , Matthew Wheeler , Reinhard Laubenbacher

A Boolean network (BN) with $n$ components is a discrete dynamical system described by the successive iterations of a function $f:\{0,1\}^n\to\{0,1\}^n$. In most applications, the main parameter is the interaction graph of $f$: the digraph…

Combinatorics · Mathematics 2021-05-06 Aymeric Picard Marchetto , Adrien Richard

Generative, temporal network models play an important role in analyzing the dependence structure and evolution patterns of complex networks. Due to the complicated nature of real network data, it is often naive to assume that the underlying…

Methodology · Statistics 2024-08-15 Daniel Cirkovic , Tiandong Wang , Xianyang Zhang

Understanding and quantifying node importance is a fundamental problem in network science and engineering, underpinning a wide range of applications such as influence maximization, social recommendation, and network dismantling. Prior…

Social and Information Networks · Computer Science 2026-02-17 Jiahui Gao , Kuang Zhou , Yuchen Zhu , Keyu Wu

We consider the problem of selecting important nodes in a random network, where the nodes connect to each other randomly with certain transition probabilities. The node importance is characterized by the stationary probabilities of the…

Methodology · Statistics 2019-01-14 Haidong Li , Xiaoyun Xu , Yijie Peng , Chun-Hung Chen

Functional complex networks have meant a pivotal change in the way we understand complex systems, being the most outstanding one the human brain. These networks have classically been reconstructed using a frequentist approach that, while…

Data Analysis, Statistics and Probability · Physics 2018-03-14 Massimiliano Zanin , Seddik Belkoura , Javier Gomez , Cesar Alfaro , Javier Cano

Dynamical networks are powerful tools for modeling a broad range of complex systems, including financial markets, brains, and ecosystems. They encode how the basic elements (nodes) of these systems interact altogether (via links) and evolve…

Physics and Society · Physics 2019-03-13 Edward Laurence , Nicolas Doyon , Louis J Dubé , Patrick Desrosiers

Learning properties of large graphs from samples has been an important problem in statistical network analysis since the early work of Goodman \cite{Goodman1949} and Frank \cite{Frank1978}. We revisit a problem formulated by Frank…

Statistics Theory · Mathematics 2019-06-18 Jason M. Klusowski , Yihong Wu

In the modeling of biological systems by Boolean networks a key problem is finding the set of fixed points of a given network. Some constructed algorithms consider certain structural properties of the interaction graph like those proposed…

Discrete Mathematics · Computer Science 2020-04-06 Julio Aracena , Luis Cabreras-Crot , Lilian Salinas

This paper examines from an experimental perspective random forests, the increasingly used statistical method for classification and regression problems introduced by Leo Breiman in 2001. It first aims at confirming, known but sparse,…

Machine Learning · Statistics 2008-11-24 Robin Genuer , Jean-Michel Poggi , Christine Tuleau

We propose a method to identify all the nodes that are relevant to compute all the conditional probability distributions for a given set of nodes. Our method is simple, effcient, consistent, and does not require learning a Bayesian network…

Machine Learning · Computer Science 2012-07-02 Jose M. Pena , Roland Nilsson , Johan Björkegren , Jesper Tegnér

Probabilistic Boolean Networks (PBNs) have been previously proposed so as to gain insights into complex dy- namical systems. However, identification of large networks and of the underlying discrete Markov Chain which describes their…

Machine Learning · Computer Science 2018-01-24 Ifigeneia Apostolopoulou , Diana Marculescu

Modeling gene regulatory networks (GRNs) is an important topic in systems biology. Although there has been much work focusing on various specific systems, the generic behavior of GRNs with continuous variables is still elusive. In…

Molecular Networks · Quantitative Biology 2014-04-23 Zhiyuan Li , Simone Bianco , Zhaoyang Zhang , Chao Tang

We study the stability of orbits in large Boolean networks with given complex topology. We impose no restrictions on the form of the update rules, which may be correlated with local topological properties of the network. While recent past…

Physics and Society · Physics 2014-09-05 Shane Squires , Andrew Pomerance , Michelle Girvan , Edward Ott

We introduce a simple one-parameter network growth algorithm which is able to reproduce a wide variety of realistic network structures but without having to invoke any global information about node degrees such as preferential-attachment…

Statistical Mechanics · Physics 2007-05-23 David M. D. Smith , Chiu Fan Lee , Neil F. Johnson

The robustness of complex networks was one of the first phenomena studied after the inception of network science. However, many contemporary presentations of this theory do not go beyond the original papers. Here we revisit this topic with…

Physics and Society · Physics 2022-02-17 Thilo Gross , Laura Barth

Automata networks, and in particular Boolean networks, are used to model diverse networks of interacting entities. The interaction graph of an automata network is its most important parameter, as it represents the overall architecture of…

Formal Languages and Automata Theory · Computer Science 2023-09-21 Maximilien Gadouleau

We study the properties of discrete-time random walks on networks formed by randomly interconnected cliques, namely, random networks of cliques. Our purpose is to derive the parameters that define the network structure -- specifically, the…

Statistical Mechanics · Physics 2025-04-24 Albano Nannini , Damián Zanette

Discrete dynamic models are a powerful tool for the understanding and modeling of large biological networks. Although a lot of progress has been made in developing analysis tools for these models, there is still a need to find approaches…

Molecular Networks · Quantitative Biology 2013-06-14 Jorge G. T. Zañudo , Réka Albert
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