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The gaits of undulating animals arise from a complex interaction of their central nervous system, muscle, connective tissue, bone, and environment. As a simplifying assumption, many previous studies have often assumed that sufficient…

Biological Physics · Physics 2023-05-31 Brian Van Stratum , Jonathan E. Clark , Kourosh Shoele

Single-molecule experiments in which force is applied to DNA or RNA molecules have enabled important discoveries of nucleic acid properties and nucleic acid-enzyme interactions. These experiments rely on a model of the polymer…

Biological Physics · Physics 2011-11-09 Jinyu Li , Philip C. Nelson , M. D. Betterton

The looping of polymers such as DNA is a fundamental process in the molecular biology of living cells, whose interior is characterised by a high degree of molecular crowding. We here investigate in detail the looping dynamics of flexible…

Soft Condensed Matter · Physics 2014-12-24 Jaeoh Shin , Andrey G. Cherstvy , Ralf Metzler

We present a unified scaling description for the dynamics of monomers of a semiflexible chain under good solvent condition in the free draining limit. We consider both the cases where the contour length $L$ is comparable to the persistence…

Biological Physics · Physics 2015-06-18 Aiqun Huang , Aniket Bhattacharya , Kurt Binder

Under high cylindrical confinement, segments of ring polymers can be localized along the long axis of the cylinder by introducing internal loops within the ring polymer. The emergent organization of the polymer segments occurs because of…

Soft Condensed Matter · Physics 2026-04-06 Sanjay Bhandarkar , Debarshi Mitra , Jürgen Horbach , Apratim Chatterji

We study theoretically the entropic elasticity of a semi-flexible polymer, such as DNA, confined to two dimensions. Using the worm-like-chain model we obtain an exact analytical expression for the partition function of the polymer pulled at…

Soft Condensed Matter · Physics 2009-11-11 Ashok Prasad , Yuko Hori , Jane' Kondev

We develop an analytical method for studying the properties of a non-interacting Wormlike Chain (WLC) in confined geometries. The mean field-like theory replaces the rigid constraints of confinement with average constraints, thus allowing…

Soft Condensed Matter · Physics 2009-11-13 Greg Morrison , D. Thirumalai

The longitudinal response of single semiflexible polymers to sudden changes in externally applied forces is known to be controlled by the propagation and relaxation of backbone tension. Under many experimental circumstances, realized, e.g.,…

Soft Condensed Matter · Physics 2011-02-25 Florian Thüroff , Benedikt Obermayer , Erwin Frey

In this paper, the looping kinetics of a long polymer chain in solution has been investigated by using two state model, where one state represents open chain polymer molecule and the other represents closed chain polymer molecule. The…

Soft Condensed Matter · Physics 2017-05-24 Moumita Ganguly , Aniruddha Chakraborty

We develop Monte Carlo simulations for uniformly charged polymers and machine learning algorithm to interpret the intra-polymer structure factor of the charged polymer system, which can be obtained from small-angle scattering experiments.…

Soft Condensed Matter · Physics 2025-11-21 Lijie Ding , Chi-Huan Tung , Jan-Michael Y. Carrillo , Wei-Ren Chen , Changwoo Do

We present a mean-field dynamical theory for single semiflexible polymers which can precisely capture, without fitting parameters, recent fluorescence correlation spectroscopy results on single monomer kinetics of DNA strands in solution.…

Soft Condensed Matter · Physics 2009-10-19 Michael Hinczewski , Roland R. Netz

We present a scaling theory and Monte Carlo (MC) simulation results for a flexible polymer chain slowly dragged by one end into a nanotube. We also describe the situation when the completely confined chain is released and gradually leaves…

Soft Condensed Matter · Physics 2009-11-13 Leonid I. Klushin , Alexander M. Skvortsov , Hsiao-Ping Hsu , Kurt Binder

The persistence length of macromolecules is one of their basic characteristics, describing their intrinsic local stiffness. However, it is difficult to extract this length from physical properties of the polymers, different recipes may give…

Soft Condensed Matter · Physics 2013-03-12 Hsiao-Ping Hsu , Wolfgang Paul , Kurt Binder

Physical aging in polymers is a fundamental yet poorly understood phenomenon, as diverse macromolecular systems exhibit remarkably similar slow dynamics. Through molecular dynamics simulations of physically crosslinked networks composed of…

Soft Condensed Matter · Physics 2025-10-16 Patrick Ilg , Clarisse Luap , Martin Kröger

We investigate the folding and forced-unbinding transitions of adsorbed semiflexible polymer chains using theory and simulations. These processes describe biologically relevant phenomena that include adhesive interactions between proteins…

Soft Condensed Matter · Physics 2007-05-23 V. Barsegov , D. Thirumalai

Intrachain contact formation rates, fundamental to the dynamics of biopolymer self-organization such as protein folding, can be monitored in the laboratory through fluorescence quenching measurements. The common approximations for the…

Condensed Matter · Physics 2009-11-07 John J. Portman

Spurred by an experimental controversy in the literature, we investigate the end-monomer dynamics of semiflexible polymers through Brownian hydrodynamic simulations and dynamic mean-field theory. Precise experimental observations over the…

Soft Condensed Matter · Physics 2009-06-20 Michael Hinczewski , Xaver Schlagberger , Michael Rubinstein , Oleg Krichevsky , Roland R. Netz

Force versus extension curves measure entropic elasticity of single polymer chain in force spectroscopy experiments. A Worm-like Chain model is used to describe force extension experiments with an intrinsic chain parameter called…

Soft Condensed Matter · Physics 2021-07-28 Vikhyaat Ahlawat , Shatruhansingh Rajput , Shivprasad Patil

We present a study of the bend angle distribution of semiflexible polymers of short and intermediate lengths within the wormlike chain model. This enables us to calculate the elastic response of a stiff molecule to a bending moment. Our…

Soft Condensed Matter · Physics 2015-06-12 Anirban Polley , Joseph Samuel , Supurna Sinha

We study the dynamics of flexible, semiflexible, and self-avoiding polymer chains moving under a Kramers metastable potential. Due to thermal noise, the polymers, initially placed in the metastable well, can cross the potential barrier, but…

Soft Condensed Matter · Physics 2013-12-05 Jaeoh Shin , Timo Ikonen , Mahendra D. Khandkar , Tapio Ala-Nissila , Wokyung Sung