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Related papers: Dynamical contribution into enzyme catalytic effic…

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Vibrational-electronic (vibronic) resonance and its role in energy and charge transfer has been experimentally and theoretically investigated in several photosynthetic proteins. Using a dimer modeled on a typical photosynthetic protein, we…

Chemical Physics · Physics 2020-09-03 Amitav Sahu , Jo Sony Kurian , Vivek Tiwari

A relationship between the preexponent of the rate constant and the distribution over activation barrier energies for enzymatic/protein reactions is revealed. We consider an enzyme solution as an ensemble of individual molecules with…

Biomolecules · Quantitative Biology 2012-11-16 A. E. Sitnitsky

Enzymes have been shown to diffuse faster in the presence of their reactants. Recently, we revealed new insights into this process of enhanced diffusion using single-particle tracking (SPT) with total internal reflection fluorescence (TIRF)…

Biological Physics · Physics 2021-01-01 Mengqi Xu , W. Benjamin Rogers , Wylie W. Ahmed , Jennifer L. Ross

It is widely recognized that the cleaving rate of a restriction enzyme on target DNA sequences is several orders of magnitude faster than the maximal one calculated from the diffusion--limited theory. It was therefore commonly assumed that…

Subcellular Processes · Quantitative Biology 2007-05-23 M. Coppey , O. Benichou , R. Voituriez , M. Moreau

In this paper we propose a novel theoretical framework for interpreting long-range dynamical correlations unveiled in proteins through NMR measurements. The theoretical rationale relies on the hypothesis that correlated motions in proteins…

Biomolecules · Quantitative Biology 2014-04-03 Francesco Piazza

Under certain conditions, applying a sequence of voltage pulses of alternating polarities across a resistive switching memory device induces a finite number of fixed-point attractors in its time-averaged dynamics, known as dynamical…

Mesoscale and Nanoscale Physics · Physics 2026-01-14 Valeriy A. Slipko , Alon Ascoli , Fernando Corinto , Yuriy V. Pershin

The resonant activation phenomenon (RAP) in a discrete system is studied using the master equation formalism. We show that the RAP corresponds to a non-monotonic behavior of the frequency dependent first passage time probability density…

Other Condensed Matter · Physics 2007-05-23 O. Flomenbom , J. Klafter

The left ventricular end-systolic pressure-volume relationship (ESPVr) is a key indicator of cardiac contractility. Despite its established importance, several studies suggested that the mechanical mode of contraction, such as isovolumetric…

Medical Physics · Physics 2024-11-12 Francesco Regazzoni , Corrado Poggesi , Cecilia Ferrantini

We introduce mapping-variable ring polymer molecular dynamics (MV-RPMD), a model dynamics for the direct simulation of multi-electron processes. An extension of the RPMD idea, this method is based on an exact, imaginary time path-integral…

Statistical Mechanics · Physics 2015-06-17 Nandini Ananth

The vibrational wave-packet dynamics of diatomic rubidium molecules (Rb2) in triplet states formed on the surface of superfluid helium nanodroplets is investigated both experimentally and theoretically. Detailed comparison of experimental…

Atomic and Molecular Clusters · Physics 2017-09-13 Barbara Grüner , Martin Schlesinger , Philipp Heister , Walter T. Strunz , Frank Stienkemeier , Marcel Mudrich

Motor proteins are active enzymatic molecules that drive a variety of biological processes, including transfer of genetic information, cellular transport, cell motility and muscles contraction. It is known that these biological molecular…

Soft Condensed Matter · Physics 2018-01-17 Luiza V. F. Gomes , Anatoly B. Kolomeisky

Given a chemical reaction going from reactant (R) to the product (P) on a potential energy surface (PES) and a collective variable (CV) that discriminates between R and P, one can define a free-energy profile (FEP) as the logarithm of the…

We formulate an analytical recursive method to generate the wave function of doped short-range resonating valence bond (RVB) states as a tool to efficiently estimate multisite entanglement as well as other physical quantities in doped…

Quantum Physics · Physics 2017-08-24 Sudipto Singha Roy , Himadri Shekhar Dhar , Debraj Rakshit , Aditi Sen De , Ujjwal Sen

The enzyme turnover rate is a fundamental parameter in enzyme kinetics, reflecting the catalytic efficiency of enzymes. However, enzyme turnover rates remain scarce across most organisms due to the high cost and complexity of experimental…

Machine Learning · Computer Science 2025-09-16 Bozhen Hu , Cheng Tan , Siyuan Li , Jiangbin Zheng , Sizhe Qiu , Jun Xia , Stan Z. Li

A probability density function describing the angular evolution of a fixed-length atom-atom vector as a L\'{e}vy rotor is derived containing just two dynamical parameters: the L\'{e}vy parameter $\alpha$ and a rotational time constant…

Chemical Physics · Physics 2022-01-05 David A. Faux , Arifah A. Rahaman , Peter J. McDonald

Molecular polaritons arise from electronic or vibrational strong coupling (ESC and VSC) with confined electromagnetic fields. While these have been widely studied, the influence of electron-nuclear dynamics in driven cavities remains…

Resonant electromagnetic actuators have been broadly used as vibration motors for mobile devices given their ability of generating relatively fast, strong, and controllable vibration force at a given resonant frequency. Mechanism of the…

Applied Physics · Physics 2018-03-20 Youngjun Cho

Intense terahertz-frequency pulses induce coherent rotational dynamics and orientation of polar molecular ensembles. Exact numerical methods for rotational dynamics are computationally not feasible for the vast majority of molecular rotors…

Quantum Physics · Physics 2015-10-14 Shimshon Kallush , Sharly Fleischer

Protein function does not solely depend on structure but often relies on dynamical transitions between distinct conformations. Despite this fact, our ability to characterize or predict protein dynamics is substantially less developed…

Statistical Mechanics · Physics 2026-05-08 Michael A. Sauer , Souvik Mondal , Brandon Neff , Sthitadhi Maiti , Matthias Heyden

Living cells employ excitable reaction-diffusion waves for internal cellular functions, in which curvature-inducing proteins are often involved. However, the role of their mechanochemical coupling is not well understood. Here, we report the…

Soft Condensed Matter · Physics 2022-08-09 Naoki Tamemoto , Hiroshi Noguchi