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Related papers: A Crash Course on Aging

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We consider a simple model of a structural glass, represented by a lattice gas with kinetic constraints in contact with a particle reservoir. Quench below the glass transition is represented by the jump of the chemical potential above a…

Statistical Mechanics · Physics 2007-05-23 Luca Peliti , Mauro Sellitto

We review recent theoretical progress on glassy dynamics, with special emphasis on the importance and universality of the ``aging regime'', which is relevant to many experimental situations. The three main subjects which we address are: (i)…

Disordered Systems and Neural Networks · Physics 2008-02-03 Jean-Philippe Bouchaud , Leticia F. Cugliandolo , Jorge Kurchan , Marc Mezard

Understanding why we age is a long-lived open problem in evolutionary biology. Aging is prejudicial to the individual and evolutionary forces should prevent it, but many species show signs of senescence as individuals age. Here, I will…

Populations and Evolution · Quantitative Biology 2012-01-24 André C. R. Martins

We survey the recent mathematical results about aging in certain simple disordered models. We start by the Bouchaud trap model. We then survey the results obtained for simple models of spin-glass dynamics, like the REM (the Random Energy…

Probability · Mathematics 2007-05-23 Gérard Ben-Arous

When complex systems are driven to extinction by some external factor, their non-stationary dynamics can present an intermittent behaviour between relative tranquility and burst of activity whose consequences are often catastrophic. To…

Physics and Society · Physics 2018-03-21 Juan V Escobar , Isaac Pérez Castillo

A simple mathematical model of the aging process for long-lived organisms is considered. The key point in this model is the assumption that the body does not have internal clocks that count out the chronological time at scales of decades.…

Other Quantitative Biology · Quantitative Biology 2019-12-30 Yu. N. Morokov

Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be understood and…

Other Quantitative Biology · Quantitative Biology 2020-08-21 Tamàs Fülöp , Mathieu Desroches , Fernando Antônio Nóbrega Santos , Serafim Rodrigues

Many complex systems experience damage accumulation which leads to aging, manifest as an increasing probability of system collapse with time. This naturally raises the question of how to maximize health and longevity in an aging system at…

Populations and Evolution · Quantitative Biology 2020-12-02 Eric D. Sun , Thomas C. T. Michaels , L. Mahadevan

These lecture notes concern information-theoretic notions of entropy. They are intended for, and have been successfully taught to, undergraduate students interested inresearch careers. Besides basic notions of analysis related to…

Mathematical Physics · Physics 2018-06-20 Vojkan Jaksic

I present a brief overview of observational, modeling and theoretical issues related to ageing calculations based on spectral steepening. These include problems such as inhomogeneous magnetic fields, diffusion of relativistic particles,…

Astrophysics · Physics 2009-10-31 Lawrence Rudnick

These lecture notes in Lie Groups are designed for a 1--semester third year or graduate course in mathematics, physics, engineering, chemistry or biology. This landmark theory of the 20th Century mathematics and physics gives a rigorous…

Differential Geometry · Mathematics 2015-03-19 Vladimir G. Ivancevic , Tijana T. Ivancevic

Some partial orderings which compare probability distributions with the expo- nential distribution, are found to be very useful to understand the phenomenon of ageing. Here, we introduce some new generalized partial orderings which de-…

Applications · Statistics 2014-10-09 Asok K. Nanda , Nil Kamal Hazra , D. K. Al-Mutairi , M. E. Ghitany

Intriguing phenomena such as subrecoil laser cooling of atoms, or aging phenomenon in glasses, have in common that the systems considered do not reach a steady-state during the experiments, although the experimental time scales are very…

Statistical Mechanics · Physics 2008-06-16 Eric Bertin , Francois Bardou

The study of immune system aging, i.e. immunosenescence, is a relatively new research topic. It deals with understanding the processes of immunodegradation that indicate signs of functionality loss possibly leading to death. Even though it…

Artificial Intelligence · Computer Science 2010-07-05 Grazziela P. Figueredo , Uwe Aickelin , Amanda Whitbrook

In this paper, we review several important features of the out-of-equilibrium dynamics of spin glasses. Starting with the simplest experiments, we discuss the scaling laws used to describe the isothermal aging observed in spin glasses after…

Disordered Systems and Neural Networks · Physics 2009-11-10 V. Dupuis , F. Bert , J. -P. Bouchaud , J. Hammann , F. Ladieu , D. Parker , E. Vincent

Aging includes both continuous gradual decline from microscopic mechanisms together with major deficit onset events such as morbidity, disability and ultimately death. These deficit events are stochastic, obscuring the connection between…

Quantitative Methods · Quantitative Biology 2025-12-25 Glen Pridham , Kenneth Rockwood , Andrew Rutenberg

There are two key paradigms for non-equilibrium dynamics: on the one hand, aging towards an equilibrium state that cannot be reached on reasonable timescales; on the other, external driving that can lead to non-equilibrium steady states. We…

Statistical Mechanics · Physics 2024-11-06 Diego Tapias , Charles Marteau , Fabián Aguirre-López , Peter Sollich

The evolutionary biology of aging is fundamental to understanding the mechanisms of aging and how to develop anti-aging treatments. Thus far most evolutionary theory concerns the genetics of aging with limited physiological integration.…

Populations and Evolution · Quantitative Biology 2025-09-22 Mirre J P Simons , Marc Tatar

At any moment in time, evolution is faced with a formidable challenge: refining the already highly optimised design of biological species, a feat accomplished through all preceding generations. In such a scenario, the impact of random…

Populations and Evolution · Quantitative Biology 2024-02-20 Alessandro Fontana , Marios Kyriazis

The random first order transition theory of the dynamics of supercooled liquids is extended to treat aging phenomena in nonequilibrium structural glasses. A reformulation of the idea of ``entropic droplets'' in terms of libraries of local…

Soft Condensed Matter · Physics 2009-11-10 Vassiliy Lubchenko , Peter G. Wolynes