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Although the survival rate of cancer patients has significantly increased due to advances in anti-cancer therapeutics, one of the major side effects of these therapies, particularly radiotherapy, is the potential manifestation of…

Quantitative Methods · Quantitative Biology 2014-11-07 Kamran Kaveh , Venkata S. K. Manem , Mohammad Kohandel , Siv Sivaloganathan

Thin elastic sheets appear in systems ranging from graphene to biological membranes, where phenomena such as wrinkling, folding, and thermal fluctuations originate from geometric nonlinearities. These effects are treated within weakly…

Soft Condensed Matter · Physics 2025-12-04 Yael Cohen , Animesh Pandey , Yafei Zhang , Cy Maor , Michael Moshe

We survey the recent mathematical results about aging in certain simple disordered models. We start by the Bouchaud trap model. We then survey the results obtained for simple models of spin-glass dynamics, like the REM (the Random Energy…

Probability · Mathematics 2007-05-23 Gérard Ben-Arous

Surfaces eroded by ion-sputtering are sometimes observed to develop morphologies which are either ripple (periodic), or rough (non-periodic). We introduce a discrete stochastic model that allows us to interpret these experimental…

The theories of stochastic quantum mechanics and stochastic electrodynamics bring to light important aspects of the quantum dynamics that are concealed in the standard formalism. Here we take further previous work regarding the connection…

Quantum Physics · Physics 2021-04-28 A. M. Cetto , L. de la Peña , A. Valdés-Hernández

The generation of entanglement produced by a local potential interaction in a bipartite system is investigated. The degree of entanglement is contrasted with the underlying classical dynamics for a Rydberg molecule (a charged particle…

Quantum Physics · Physics 2007-05-23 M. Lombardi , A. Matzkin

The simulation of transmission electron microscopy (TEM) images or diffraction patterns is often required to interpret their contrast and extract specimen features. This is especially true for high-resolution phase-contrast imaging of…

Materials Science · Physics 2021-03-30 Jacob Madsen , Timothy J. Pennycook , Toma Susi

We describe a new phenomenon in models of coalescence and fragmentation, that of gel-shatter cycles. These are dynamical, unforced, stochastic cycles in which slow, approximately deterministic coalescence up to and beyond gelation is…

Dynamical Systems · Mathematics 2021-05-26 Brennen T. Fagan , Niall J. MacKay , Dmitri O. Pushkin , A. Jamie Wood

The paper presents a computational stochastic model of virtual cells irradiation, based on Quasi-Markov Chain Monte Carlo method and using biophysical input. The model is based on a stochastic tree of probabilities for each cell of the…

Biological Physics · Physics 2014-12-23 Krzysztof Wojciech Fornalski

In quantum many-body systems, measurements can induce qualitative new features, but their simulation is hindered by the exponential complexity involved in sampling the measurement results. We propose to use machine learning to assist the…

Quantum Physics · Physics 2024-12-03 Yuchen Zhu , Molei Tao , Yuebo Jin , Xie Chen

Purpose of review: The epithelial-Mesenchymal Transition (EMT) and the generation of Cancer Stem Cells (CSC) are two fundamental aspects contributing to tumor growth, acquisition of resistance to therapy, formation of metastases, and tumor…

Molecular Networks · Quantitative Biology 2018-11-07 Federico Bocci , Herbert Levine , José Nelson Onuchic , Mohit Kumar Jolly

A stochastic genetic model for biological aging is introduced bridging the gap between the bit-string Penna model and the Pletcher-Neuhauser approach. The phenomenon of exponentially increasing mortality function at intermediate ages and…

Statistical Mechanics · Physics 2007-05-23 Zhi-Feng Huang , Dietrich Stauffer

Single-cell gene expression measurements encode variability spanning molecular noise, cell-to-cell heterogeneity, and technical artifacts. Mechanistic stochastic models provide powerful approaches to disentangle these sources, yet inferring…

Quantitative Methods · Quantitative Biology 2025-09-19 Christopher E. Miles

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

Probability · Mathematics 2022-04-27 Nam H Nguyen , Marek Kimmel

Pinning particles at random in supercooled liquids is a promising route to make substantial progress on the glass transition problem. Here we develop a mean-field theory by studying the equilibrium and non-equilibrium dynamics of the…

Disordered Systems and Neural Networks · Physics 2012-12-18 Chiara Cammarota , Giulio Biroli

Under rapid undercooling, glass forming liquids freeze in an amorphous state that can equilibrate only on enormously long time-scales, This is the characteristic sign of aging, which has been observed in a wide range of systems. Brownian…

Statistical Mechanics · Physics 2023-03-01 Karina I Mazzitello , Daniel G Zarlenga , Fereydoon Family , Constancio M Arizmendi

The concepts and methods used for the study of disordered systems have proven useful in the analysis of the evolution equations of quantum chromodynamics in the high-energy regime: Indeed, parton branching in the semi-classical…

High Energy Physics - Phenomenology · Physics 2015-07-06 Stephane Munier

The mortality rate of many complex multicellular organisms increase with age, which suggests that net aging damage is accumulative, despite remodeling processes. But how exactly do little mishaps in the cellular level accumulate and spread…

Tissues and Organs · Quantitative Biology 2017-12-12 Daniel Suma , Aylin Acun , Pinar Zorlutuna , Dervis Can Vural

Aging, as defined in terms of the slope of the probability of death versus time (hazard curve), is a generic phenomenon observed in nearly all complex systems. Theoretical models of aging predict hazard curves that monotonically increase in…

Biological Physics · Physics 2023-12-20 Cagatay Eskin , Dervis C. Vural

We revisit the classic problem of elastic cavitation within the framework of stochastic elasticity. For the deterministic elastic problem, involving homogeneous isotropic incompressible hyperelastic spheres under radially symmetric tension,…

Soft Condensed Matter · Physics 2019-08-13 L. Angela Mihai , Danielle Fitt , Thomas E. Woolley , Alain Goriely