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Single and collective cell migration are fundamental processes critical for physiological phenomena ranging from embryonic development and immune response to wound healing and cancer metastasis. To understand cell migration from a physical…

Biological Physics · Physics 2023-10-10 David B. Brückner , Chase P. Broedersz

The latent stochastic block model is a flexible and widely used statistical model for the analysis of network data. Extensions of this model to a dynamic context often fail to capture the persistence of edges in contiguous network…

Methodology · Statistics 2018-04-16 Riccardo Rastelli

We use molecular dynamics simulations to study a model of the gelation transition with a dynamic bond forming procedure. After establishing evidence for 3D percolation as the static universality class, we turn our attention to the dynamics…

Statistical Mechanics · Physics 2007-05-23 Sune Norhoj Jespersen

We present an efficient method to perform overdamped Brownian dynamics simulations in external force fields and for particle interactions that include a hardcore part. The method applies to particle motion in one dimension, where it is…

Statistical Mechanics · Physics 2026-02-23 Alexander P. Antonov , Sören Schweers , Artem Ryabov , Philipp Maass

We consider a neural network with adapting synapses whose dynamics can be analitically computed. The model is made of $N$ neurons and each of them is connected to $K$ input neurons chosen at random in the network. The synapses are…

Disordered Systems and Neural Networks · Physics 2009-10-30 G. Lattanzi , G. Nardulli , G. Pasquariello , S. Stramaglia

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

Tissues and Organs · Quantitative Biology 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

The dielectric behavior of a linear cluster of two or more living cells connected by tight junctions is analyzed using a spectral method. The polarizability of this system is obtained as an expansion over the eigenmodes of the linear…

Biological Physics · Physics 2010-02-12 Titus Sandu , Daniel Vrinceanu , Eugen Gheorghiu

Spatial self-similarity is a hallmark of critical phenomena. We investigate the dynamic process of percolation, in which bonds are incrementally inserted to an empty lattice until fully occupied, and track the gaps describing the changes in…

Statistical Mechanics · Physics 2024-11-08 Mingzhong Lu , Yu-Feng Song , Ming Li , Youjin Deng

Metastability is a common obstacle to performing long molecular dynamics simulations. Many numerical methods have been proposed to overcome it. One method is parallel replica dynamics, which relies on the rapid convergence of the underlying…

Numerical Analysis · Mathematics 2015-05-20 Andrew Binder , Tony Lelièvre , Gideon Simpson

The statistical physics and dynamics of double supported bilayers are studied theoretically. The main goal in designing double supported lipid bilayers is to obtain model systems of biomembranes: the upper bilayer is meant to be almost…

Soft Condensed Matter · Physics 2015-03-13 Manoel Manghi , Nicolas Destainville

Motivated by a general principle governing regulation mechanisms in biological cells, we investigate a general interaction scheme between different populations of particles and specific particles, referred to as agents. Assuming that each…

Probability · Mathematics 2023-10-10 Vincent Fromion , Philippe Robert , Jana Zaherddine

A dynamical formulation of coupled cluster theory is derived using a variational principle. By allowing time-dependent single-particle functions, a high degree of adaptivity is introduced, allowing complex systems to be simulated with high…

Quantum Physics · Physics 2014-11-25 Simen Kvaal

We study the steady state of the abelian sandpile models with stochastic toppling rules. The particle addition operators commute with each other, but in general these operators need not be diagonalizable. We use their abelian algebra to…

Statistical Mechanics · Physics 2010-10-01 Tridib Sadhu , Deepak Dhar

Cell adhesion proteins typically form stable clusters that anchor the cell membrane to its environment. Several works have suggested that cell membrane protein clusters can emerge from a local feedback between the membrane curvature and the…

Soft Condensed Matter · Physics 2023-08-16 Shao-Zhen Lin , Jacques Prost , Jean-Francois Rupprecht

The zero range process is of particular importance as a generic model for domain wall dynamics of one-dimensional systems far from equilibrium. We study this process in one dimension with rates which induce an effective attraction between…

Statistical Mechanics · Physics 2018-04-26 Stefan Grosskinsky , Gunter M. Schuetz , Herbert Spohn

We analyze the stability of micro-domains of ligand-receptor bonds that mediate the adhesion of biological model membranes. After evaluating the effects of membrane fluctuations on the binding affinity of a single bond, we characterize the…

Soft Condensed Matter · Physics 2012-11-22 Daniel Schmidt , Timo Bihr , Udo Seifert , Ana-Sunčana Smith

The discerning behavior of living systems relies on accurate interactions selected from the lot of molecular collisions occurring in the cell. To ensure the reliability of interactions, binding partners are classically envisioned as finely…

Molecular Networks · Quantitative Biology 2016-09-28 Denis Michel , Benjamin Boutin , Philippe Ruelle

A novel mechanism for cell differentiation is proposed, based on the dynamic clustering in a globally coupled chaotic system. A simple model with metabolic reaction, active transport of chemicals from media, and cell division is found to…

adap-org · Physics 2009-10-22 Kunihiko Kaneko , Tetsuya Yomo

Using simulations of hard rods in smectic-A states, we find non-gaussian diffusion and heterogeneous dynamics due to the equilibrium periodic smectic density profiles, which give rise to permanent barriers for layer-to-layer diffusion. This…

Soft Condensed Matter · Physics 2009-12-15 A. Patti , D. El Masri , R. van Roij , M. Dijkstra

A realistic continuous-time dynamics for fiber bundles is introduced and studied both analytically and numerically. The equation of motion reproduces known stationary-state results in the deterministic limit while the system under…

Statistical Mechanics · Physics 2009-11-10 M. Y. Choi , J. Choi , B. -G. Yoon
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