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Electroporation is a physical method to induce the uptake of therapeutic drugs and DNA, by eukaryotic cells and tissues. The phenomena behind electro-mediated membrane permeabilization to plasmid DNA have been shown to be significantly more…

Deformation of single stranded DNA in translocation process before reaching the pore is investigated. By solving the Laplace equation in a suitable coordinate system and with appropriate boundary conditions, an approximate solution for the…

Soft Condensed Matter · Physics 2014-11-18 Farnoush Farahpour , Azadeh Maleknejad , Fathollah Varnik , Mohammad Reza Ejtehadi

The dependence of DNA assemblies conductance on relative humidity is investigated theoretically. Following earlier suggestions, we consider the ionic conductivity through the layers of water adsorbed by DNA molecules. The increase in…

Chemical Physics · Physics 2015-05-14 J. M. Leveritt , S. Tesar , C. Dibaya , R. Shrestha , A. L. Burin

Supercapacitors have been attracting significant attention as promising energy storage devices. However, the voltage window limitation associated with electrolyte solutions has hindered the improvement of their capacitance. To address this…

Chemical Physics · Physics 2023-06-27 Weihang Gao , Teng Zhao , Shian Dong , Xingyi Huang , Zhenli Xu

We use a coarse-grained molecular model to study the self-assembly process of complexes of cationic and neutral lipids with DNA molecules ("lipoplexes") - a promising nonviral carrier of DNA for gene therapy. We identify the resulting…

Soft Condensed Matter · Physics 2011-05-31 Oded Farago , Niels Grønbech-Jensen

In the past two decades, many research groups worldwide have tried to understand and categorize simple regimes in the charge transfer of such biological systems as DNA. Theoretically speaking, the lack of exact theories for electron-nuclear…

Chemical Physics · Physics 2014-05-06 Pablo Ramos , Michele Pavanello

Knowledge of the mechanisms of interaction between self-aggregating peptides and nucleic acids or other polyanions is key to the understanding of many aggregation processes underlying several human diseases (e.g. Alzheimer's and Parkinson's…

The development of advanced electrochemical devices for energy conversion and storage requires fine tuning of electrode reactions, which can be accomplished by altering the electrode/solution interface structure. Particularly, in case of an…

Soft Condensed Matter · Physics 2020-07-02 Yu. A. Budkov , A. V. Sergeev , S. V. Zavarzin , A. L. Kolesnikov

A theory is presented for the binding of small molecules such as surfactants to semiflexible polymers. The persistence length is assumed to be large compared to the monomer size but much smaller than the total chain length. Such polymers…

Soft Condensed Matter · Physics 2009-09-25 Haim Diamant , David Andelman

The effective force between two parallel DNA molecules is calculated as a function of their mutual separation for different valencies of counter- and salt ions and different salt concentrations. Computer simulations of the primitive model…

Soft Condensed Matter · Physics 2009-11-10 E. Allahyarov , G. Gompper , H. Löwen

We have studied the response of surface properties and swelling behaviors of annealed poly(2-vinyl pyridine) (P2VP) brushes covalently tethered to solid planar surfaces to divalent salts in aqueous solutions at varied pH values. Results…

Soft Condensed Matter · Physics 2015-11-10 Chen Qu

Counterion distribution around an isolated flexible polyelectrolyte in the presence of a divalent salt is evaluated using the adsorption model [M. Muthukumar, J. Chem. Phys. {\bf 120}, 9343 (2004)] that considers Bjerrum length, salt…

Soft Condensed Matter · Physics 2008-12-29 Arindam Kundagrami , M. Muthukumar

This study investigates the interplay between Strong Coupling (SC) attraction and hydration repulsion in nanoconfined water between like-charged phospholipid layers. It challenges the assumption that SC attraction requires multivalent…

We have managed to correlate the stability constants of complex formation, which can be registered in equilibrium state, to the dynamic characteristic of the complex lifetime. Thus, the principal concept of molecular biophysics regarding…

We study the effect of surfactant on the pairwise interactions of drops in an applied uniform DC electric field using a combination of numerical simulations based on a boundary integral formulation and an analytical theory assuming small…

Fluid Dynamics · Physics 2020-12-03 Chiara Sorgentone , Petia Vlahovska

Understanding how soft matter systems, including biological ones, can develop collective electromagnetic phenomena under external fields at ambient conditions remains a central challenge, as thermal fluctuations are generally expected to…

Biological Physics · Physics 2026-01-21 Mariusz Pietruszka

Polymer topology, which plays a principal role in the rheology of polymeric fluids, and non-equilibrium materials, which exhibit time-varying rheological properties, are topics of intense investigation. Here, we push composites of circular…

Soft Condensed Matter · Physics 2023-05-23 Juexin Marfai , Ryan J. McGorty , Rae M. Robertson-Anderson

Understanding the behavior of charged complex fluids is crucial for a plethora of important industrial, technological, and medical applications. Using coarse-grained molecular dynamics simulations, here we investigate the properties of a…

Soft Condensed Matter · Physics 2022-08-04 Debarshee Bagchi

When multivalent salts are added to dilute DNA solution, the DNA chains condense into bundles of a well-defined size. We explore two physical problems motivated by this phenomenon: the origin of the attractive interactions between the…

Soft Condensed Matter · Physics 2007-05-23 Bae-Yeun Ha , Andrea J. Liu

We explore interactions between equally charged surfaces, in the presence of simple salt and either neutral or monovalently charged polyampholytes. We consider the possibility of using these charged polymers as crude models of ion clusters.…

Soft Condensed Matter · Physics 2026-03-19 David Ribar , Clifford E Woodward , Jan Forsman