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While often believed to be a passive agent that merely exploits its host's metabolism, influenza virus has recently been shown to actively move across glycan-coated surfaces. This form of enzymatically driven surface motility is currently…

Soft Condensed Matter · Physics 2021-06-02 Falko Ziebert , Igor M. Kulić

We investigated three models of Brownian motors which convert rotational diffusion into directed translational motion by switching on and off a potential. In the first model a spatially asymmetric potential generates directed translational…

Statistical Mechanics · Physics 2009-11-11 Brian Geislinger , Ryoichi Kawai

We aim to identify the control principles governing the adaptable formation of non-equilibrium structures in actomyosin networks. We build a phenomenological model and predict that biasing the energy dissipated by molecular motors should…

Active gels perform key mechanical roles inside the cell, such as cell division, motion and force sensing. The unique mechanical properties required to perform such functions arise from the interactions between molecular motors and…

Soft Condensed Matter · Physics 2022-08-16 Andrés Córdoba

Actin and myosin drive many instances of force generation, deformation, and shape change in cells, tissues, and organisms. In particular, cytoskeletal actomyosin is remarkable in its adaptive architecture, responding to a host of…

Soft Condensed Matter · Physics 2025-12-18 James Clarke , Hyunjae Lee , Kyla Wong , Julia Glenn , Aniket Marne , Yoichi Miyahara , José Alvarado

In systems possessing spatial or dynamical symmetry breaking, Brownian motion combined with symmetric external input signals, deterministic or random, alike, can assist directed motion of particles at the submicron scales. In such cases,…

Statistical Mechanics · Physics 2009-06-05 Peter Hanggi , Fabio Marchesoni

Bartussek, Hanggi and Kissner studied a rocking ratchet system, in which a Brownian particle is subject to an asymmetric periodic potential together with an oscillating force, and found that the direction of the macroscopic current can be…

Soft Condensed Matter · Physics 2009-01-09 Kumiko Hayashi , Hisatsugu Yamasaki , Mitsunori Takano

Actomyosin networks are major structural components of the cell. They provide mechanical integrity and allow dynamic remodeling of eukaryotic cells, self-organizing into the diverse patterns essential for development. We provide a…

Biological Physics · Physics 2012-04-17 Shenshen Wang , Peter G. Wolynes

The cooperative action of many molecular motors is essential for dynamic processes such as cell motility and mitosis. This action can be studied by using motility assays in which the motion of cytoskeletal filaments over a surface coated…

Soft Condensed Matter · Physics 2009-06-01 Barak Gilboa , David Gillo , Oded Farago , Anne Bernheim-Groswasser

Cortical actin networks are highly dynamic and play critical roles in shaping the mechanical properties of cells. The actin cytoskeleton undergoes significant reorganization over the course of the cell cycle, when cortical actin transitions…

Quantitative Methods · Quantitative Biology 2022-07-22 Maria-Veronica Ciocanel , Aravind Chandrasekaran , Carli Mager , Qin Ni , Garegin Papoian , Adriana Dawes

Several stochastic models called thermal ratchet models have been recently proposed to analyze the motor proteins such as myosin and kinesin,etc. We propose a method to study the energetics of those models, and show how the rate of energy…

Statistical Mechanics · Physics 2016-08-31 Ken Sekimoto

Based on the Stochastic Inclined Rods Model (SIRM) proposed by H. Matsuura and M. Nakano, we study the microscopic motion of actin myosin system including the motion of the G-actin. Our model is composed of an inclined spring (rod), a…

Biological Physics · Physics 2007-05-23 Bao-quan Ai , Xian-ju Wang , Guo-tao Liu , Liang-gang Liu , M. Nakano , H. Matsuura

We consider a primary model of ac-driven Brownian motors, i.e., a classical particle placed in a spatial-time periodic potential and coupled to a heat bath. The effects of fluctuations and dissipations are studied by a time-dependent…

Statistical Mechanics · Physics 2009-07-01 S. Denisov , P. Hanggi , J. L. Mateos

Myosin II plays a pivotal role in muscle contraction by generating force through the cooperative action of multiple motors on actin filaments. In this study, we integrate the nonlinear elasticity of the neck linker in individual myosin II…

Biological Physics · Physics 2023-06-21 Beibei Shen , Yunxin Zhang

The diffusion of a molecular motor in the presence of a constant external force is considered on the basis of a simple theoretical model. The motor is represented by a Brownian particle moving in a series of parabolic potentials placed…

Statistical Mechanics · Physics 2016-06-01 Ryota Shinagawa , Kazuo Sasaki

The pump process of the ratchet model inspired by the $F_o$ rotatory motor of ATP synthase is investigated. In this model there are two kinds of characteristic time. One is dynamical, the relaxation time of the system. Others are chemical,…

Biological Physics · Physics 2007-05-23 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

Myosin II is the muscle molecular motor that works in two bipolar arrays in each thick filament of the striated (skeletal and cardiac) muscle, converting the chemical energy into steady force and shortening by cyclic ATP--driven…

A jump-diffusion process is proposed to describe the displacements performed by single myosin heads along actin filaments during the rising phases. The process consists of the superposition of a Wiener and a jump process, with jumps…

Soft Condensed Matter · Physics 2007-05-23 A. Buonocore , A. Di Crescenzo , B. Martinucci , L. M. Ricciardi

We study subdiffusive ratchet transport in periodically and randomly flashing potentials. Central Brownian particle is elastically coupled to surrounding auxiliary Brownian quasi-particles which account for the influence of viscoelastic…

Statistical Mechanics · Physics 2012-06-04 Vasyl Kharchenko , Igor Goychuk

Transport phenomena in spatially periodic systems far from thermal equilibrium are considered. The main emphasize is put on directed transport in so-called Brownian motors (ratchets), i.e. a dissipative dynamics in the presence of thermal…

Statistical Mechanics · Physics 2009-10-31 Peter Reimann