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We use a coarse grained molecular model of supported lipid bilayers to study the formation of adhesion domains. We find that this process is a first order phase transition, triggered by a combination of pairwise short range attractive…

Soft Condensed Matter · Physics 2015-06-22 Nadiv Dharan , Oded Farago

Simulating protein-membrane interactions is an important and dynamic area of research. A proper definition of electrostatic forces on membrane surfaces is necessary for developing electromechanical models of protein-membrane interactions.…

Analysis of PDEs · Mathematics 2013-09-24 Michael Mikucki , Y. C. Zhou

Molecular dynamic simulations were employed to study a water-like model confined between hydrophobic and hydrophilic plates. The phase behavior of this system is obtained for different distances between the plates and particle-plate…

Soft Condensed Matter · Physics 2015-06-17 Leandro B. Krott , Marcia C. Barbosa

We study thermal fluctuations of a free-standing bilayer graphene subject to vanishing external tension. Within a phenomenological theory, the system is described as a stack of two continuum crystalline membranes, characterized by finite…

Mesoscale and Nanoscale Physics · Physics 2020-12-01 Achille Mauri , David Soriano , Mikhail I. Katsnelson

We propose a very simple but 'realistic' model of amphiphilic bilayers,simple enough to be able to include a large number of molecules in the sample, but nevertheless detailed enough to include molecular charge distributions, flexible…

Soft Condensed Matter · Physics 2009-11-13 Z. Gamba

Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

Soft Condensed Matter · Physics 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

Biomembranes consisting of two opposing phospholipid monolayers, which comprise the so-called lipid bilayer, are largely responsible for the dual solid-fluid behavior of individual cells and viruses. Quantifying the mechanical…

Biological Physics · Physics 2024-05-27 Naoki Takeishi , Masaya Santo , Naoto Yokoyama , Shigeo Wada

A cell membrane can be simply regarded as composite material consisting of lipid bilayer, membrane cytoskeleton beneath lipid bilayer, and proteins embedded in lipid bilayer and linked with membrane cytoskeleton if one only concerns its…

Other Quantitative Biology · Quantitative Biology 2007-06-26 Z. C. Tu , R. An , Z. C. Ou-Yang

The paper presents a complete research cycle comprising continuum-based modeling, computational framework development, and validation setup to predict phase separation and surface hydrodynamics in lipid bilayer membranes. We starting with…

Numerical Analysis · Mathematics 2025-10-14 Maxim Olshanskii , Annalisa Quaini

We devise a soft, solvent-free, coarse-grained model for lipid bilayer membranes. The non-bonded interactions take the form of a weighted-density functional which allows us to describe the thermodynamics of self-assembly and packing effects…

Soft Condensed Matter · Physics 2010-06-09 Martin Hömberg , Marcus Müller

Porous membranes are thin solid structures that allow the flow to pass through their tiny openings, called pores. Flow inertia may play a significant role in several filtration flows of natural and engineering interest. Here, we develop a…

Biomembranes, which are mainly composed of neutral and charged lipids, exhibit a large variety of functional structures and dynamics. Here, we report a coarse-grained molecular dynamics (MD) simulation of the phase separation and…

Soft Condensed Matter · Physics 2016-11-07 Hiroaki Ito , Yuji Higuchi , Naofumi Shimokawa

We introduce and test via molecular simulation a simple model for predicting the manner in which interparticle interactions and thermodynamic conditions impact the single-particle free-volume distributions of equilibrium fluids. The model…

Soft Condensed Matter · Physics 2007-05-23 William P. Krekelberg , Venkat Ganesan , Thomas M. Truskett

In this article we review the present knowledge on the elastic properties of membranes of biological origin. Assuming the fluid mosaic hypothesis, we consider the phospholipid bilayer as the structural base of a biological membrane. We…

Soft Condensed Matter · Physics 2015-06-11 L. Martínez-Balbuena , A. Maldonado-Arce , E. Hernández-Zapata

Understanding how different classes of molecules move across biological membranes is a prerequisite to predicting a solute's permeation rate, which is a critical factor in the fields of drug design and pharmacology. We use biased Molecular…

Biological Physics · Physics 2018-05-16 Nihit Pokhrel , Lutz Maibaum

Biological membranes are host to proteins and molecules which may form domain-like structures resulting in spatially-varying material properties. Vesicles with such heterogeneous membranes can exhibit intricate shapes at equilibrium and…

Soft Condensed Matter · Physics 2023-06-22 Prerna Gera , David Salac , Saverio E. Spagnolie

Compared to pure fluids, binary mixtures display a very diverse phase behavior, which depends sensitively on the parameters of the microscopic potential. Here we investigate the phase diagrams of simple model mixtures by use of a…

Soft Condensed Matter · Physics 2009-11-07 A. Parola , D. Pini , L. Reatto , M. Tau

The filtration of fluid in 2D porous medium is simulated by the molecular dynamics technique. The high concentration of fluid is created at the initial point in time and the number of fluid particles is investigated in all porous. The…

Fluid Dynamics · Physics 2007-05-23 Marat N. Ovchinnikov

The rich thermotropic behavior of lipid bilayers is addressed using phenomenological theory informed by many experiments. The most recent experiment not yet addressed by theory has shown that the tilt modulus in DMPC lipid bilayers…

Soft Condensed Matter · Physics 2023-07-12 John F. Nagle

In hydrodynamic descriptions of lipid bilayers, the membrane is often approximated as being impermeable to the surrounding, solute-containing fluid. However, biological and in vitro lipid membranes are influenced by their permeability and…

Soft Condensed Matter · Physics 2026-02-24 Amaresh Sahu
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