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We consider a one-dimensional diffusion process with coefficients that are periodic outside of a finite 'interface region'. The question investigated in this article is the limiting long time / large scale behaviour of such a process under…

Probability · Mathematics 2010-05-14 Martin Hairer , Charles Manson

In many biological systems, the movement of individual agents is commonly characterized as having multiple qualitatively distinct behaviors that arise from various biophysical states. This is true for vesicles in intracellular transport,…

Subcellular Processes · Quantitative Biology 2022-07-25 Maria-Veronica Ciocanel , John Fricks , Peter R. Kramer , Scott A. McKinley

Fluorescence microscopy is widely employed for the analysis of living biological samples; however, the utility of the resulting recordings is frequently constrained by noise, temporal variability, and inconsistent visualisation of signals…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Hassan Eshkiki , Sarah Costa , Mostafa Mohammadpour , Farinaz Tanhaei , Christopher H. George , Fabio Caraffini

Optical tweezers setup is often used to probe the motion of individual tracer particle, which promotes the study of relaxation dynamics of a generic process confined in a harmonic potential. We uncover the dependence of ensemble- and…

Statistical Mechanics · Physics 2020-04-15 Xudong Wang , Yao Chen , Weihua Deng

We show in detail some results, outlined in a previous paper regarding the case of Brownian motion (BM), about the distribution of the $n$th-passage time of a one-dimensional diffusion obtained by a space or time transformation of BM,…

Probability · Mathematics 2018-04-12 Mario Abundo , Maria Beatrice Scioscia Santoro

Reward Feedback Learning (ReFL) has recently shown great potential in aligning model outputs with human preferences across various generative tasks. In this work, we introduce a ReFL framework, named DiffusionReward, to the Blind Face…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Bin Wu , Wei Wang , Yahui Liu , Zixiang Li , Yao Zhao

Light scattering inhibits high-resolution optical imaging, manipulation and therapy deep inside biological tissue by preventing focusing. To form deep foci, wavefront-shaping and time-reversal techniques that break the optical diffusion…

Optics · Physics 2015-06-04 Cheng Ma , Fengbo Zhou , Yan Liu , Lihong V. Wang

We introduce a simulation-based, amortised Bayesian inference scheme to infer the parameters of random walks. Our approach learns the posterior distribution of the walks' parameters with a likelihood-free method. In the first step a graph…

Machine Learning · Computer Science 2022-12-07 Hippolyte Verdier , François Laurent , Alhassan Cassé , Christian Vestergaard , Jean-Baptiste Masson

We investigated three models of Brownian motors which convert rotational diffusion into directed translational motion by switching on and off a potential. In the first model a spatially asymmetric potential generates directed translational…

Statistical Mechanics · Physics 2009-11-11 Brian Geislinger , Ryoichi Kawai

We study a model for the translocation of proteins across membranes through a nanopore using a ratcheting mechanism. When the protein enters the nanopore it diffuses in and out of the pore according to a Brownian motion. Moreover, it is…

Probability · Mathematics 2011-07-27 A. Depperschmidt , N. Ketterer , P. Pfaffelhuber

The random motion of a Brownian particle confined in some finite domain is considered. Quite generally, the relevant statistical properties involve infinite series, whose coefficients are related to the eigenvalues of the diffusion…

Statistical Mechanics · Physics 2010-04-26 Thomas Bickel

In this article, we introduce the new approach "fluorescence grid based aggregation (FGBA)" to justify a dynamical model of protein expression using experimental fluorescence histograms. In this approach, first, we describe the dynamics of…

Probability · Mathematics 2015-03-19 Anahita Mirtabatabaei , Francesco Bullo , Mustafa Khammash

We monitored isotropic spreading of mouse embryonic fibroblasts on fibronectin-coated substrates. Cell adhesion area versus time was measured via total internal reflection fluorescence microscopy. Spreading proceeds in well-defined phases.…

Cell Behavior · Quantitative Biology 2009-11-10 H. -G. Doebereiner , B. J. Dubin-Thaler , G. Giannone , H. S. Xenias , M. P. Sheetz

This article introduces a novel construction of the two-dimensional fractional Brownian motion (2D fBm) with dependent components. Unlike similar models discussed in the literature, our approach uniquely accommodates the full range of model…

We study the paraxial wave equation with a randomly perturbed index of refraction, which can model the propagation of a wave beam in a turbulent medium. The random perturbation is a stationary and isotropic process with a general form of…

Analysis of PDEs · Mathematics 2022-05-10 Liliana Borcea , Josselin Garnier , Knut Solna

Fast radio bursts (FRBs) are bright, millisecond-duration radio pulses whose origins are unknown. To date, only one (FRB 121102) out of several dozen has been seen to repeat, though the extent to which it is exceptional remains unclear. We…

High Energy Astrophysical Phenomena · Physics 2018-07-11 Liam Connor , Emily Petroff

We use coarse grained molecular dynamics simulations to investigate diffusion properties of sheared lipid membranes with embedded transmembrane proteins. In membranes without proteins, we find normal in-plane diffusion of lipids in all flow…

Biological Physics · Physics 2013-09-10 Atefeh Khoshnood , Mir Abbas Jalali

In the diffusion-collision model, the unfolding or backward rates are given by the likelihood of secondary structural cluster dissociation. In this work, we introduce a backward rate calculation modeled from a Kramers-type thermal tunneling…

Soft Condensed Matter · Physics 2007-05-23 Chris Beck , Xavier Siemens

Fast radio bursts (FRBs) are short-duration radio transients of unknown origin. Thus far, they have been blindly detected at millisecond timescales with dispersion measures (DMs) between 110--2600\,pc\,cm$^{-3}$. However, the observed pulse…

High Energy Astrophysical Phenomena · Physics 2019-07-10 Liam Connor

Anomalous-diffusion, the departure of the spreading dynamics of diffusing particles from the traditional law of Brownian-motion, is a signature feature of a large number of complex soft-matter and biological systems. Anomalous-diffusion…

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