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Microfluidic devices are increasingly used in synchrotron-based experiments to deliver and probe liquid samples, offering advantages such as minimal sample consumption and reduced radiation damage. Despite their growing use, few devices…

X-ray absorption spectroscopy (XAS) is a powerful characterization technique for probing the local chemical environment of absorbing atoms. However, analyzing XAS data presents significant challenges, often requiring extensive,…

Materials Science · Physics 2025-04-16 Shubha R. Kharel , Fanchen Meng , Xiaohui Qu , Matthew R. Carbone , Deyu Lu

We demonstrate that powder diffraction data can be collected from sub-micron crystals of a mbrane protein with nearly two orders of magnitude more atoms than the molecules commonly used for powder diffraction. The crystals of photosystem-1…

Combinations of spectroscopic analysis and microscopic techniques are used across many disciplines of scientific research, including material science, chemistry and biology. X-ray spectromicroscopy, in particular, is a powerful tool used…

Medical Physics · Physics 2023-10-17 Oliver Townsend , Silvia Gazzola , Sergey Dolgov , Paul Quinn

The PandaX project consists of a series of xenon-based experiments that are used to search for dark matter (DM) particles and to study the fundamental properties of neutrinos. The next DM experiment PandaX-4T will be using 4 ton liquid…

Instrumentation and Detectors · Physics 2020-12-15 Qibin Zheng , Yanlin Huang , Di Huang , Jianglai Liu , Xiangxiang Ren , Anqing Wang , Meng Wang , Jijun Yang , Binbin Yan , Yong Yang

Microfluidic mixing is an important means for in-situ sample preparation and handling while Small Angle X-Ray Scattering (SAXS) is a proven tool for characterising (macro-)molecular structures. In combination those two techniques enable…

As data science and machine learning methods are taking on an increasingly important role in the materials research community, there is a need for the development of machine learning software tools that are easy to use (even for nonexperts…

Computational Physics · Physics 2020-06-26 Ryan Jacobs , Tam Mayeshiba , Ben Afflerbach , Luke Miles , Max Williams , Matthew Turner , Raphael Finkel , Dane Morgan

Future strategic X-ray missions, such as the Advanced X-ray Imaging Satellite (AXIS) and those targeted by the Great Observatories Maturation Program (GOMaP), require fast, low-noise X-ray imaging spectrometers. To achieve the speed and…

We report on the design, construction and operation of a low background x-ray detection line composed of a shielded Micromegas (micromesh gaseous structure) detector of the microbulk technique. The detector is made from radiopure materials…

X-ray computed tomography (XCT) is an important tool for high-resolution non-destructive characterization of additively-manufactured metal components. XCT reconstructions of metal components may have beam hardening artifacts such as cupping…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Obaidullah Rahman , Singanallur V. Venkatakrishnan , Luke Scime , Paul Brackman , Curtis Frederick , Ryan Dehoff , Vincent Paquit , Amirkoushyar Ziabari

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

The open-source PyNX toolkit [Favre-Nicolin et al (2011) arXiv:1010.2641, Mandula et al (2016)] has been extended to provide tools for coherent X-ray imaging data analysis and simulation. All calculations can be executed on graphical…

Optical scanning is a prevalent technique for optical neural interfaces where light delivery with high spatial and temporal precision is desired. However, due to the sequential nature of point-scanning techniques, the settling time of…

Gas time projection chambers (TPCs) with Micromegas pixelated readouts are being used in dark matter searches and other rare event searches, due to their potential in terms of low background levels, energy and spatial resolution, gain, and…

Atomic force microscopes have proved to be fundamental research tools in many situations where a gentle imaging process is required, and in a variety of environmental conditions, such as the study of biological samples. Among the possible…

Systems and Control · Computer Science 2023-01-05 Marco Coraggio , Martin Homer , Oliver D. Payton , Mario di Bernardo

Analysis of XRD diffraction patterns is one of the keystones of materials science and materials research. With the advancement of data-driven methods for materials design, candidate materials can be quickly screened for the study of a…

Within the scientific goals of the THESEUS ESA/M5 candidate mission, a critical item is a fast (within a few s) and accurate (<15 arcmin) Gamma-Ray Burst and high-energy transient location from a few keV up to hard X-ray energy band. For…

For over three decades, scanning probe microscopy (SPM) has been a key method for exploring material structures and functionalities at nanometer and often atomic scales in ambient, liquid, and vacuum environments. Historically, SPM…

Chemical recycling of plastics to its constituent monomers is a promising solution to develop a sustainable circular plastic economy. An in-situ X-ray absorption spectra (XAS) characterization is an important way to understand the…

Materials Science · Physics 2024-10-02 Zhengxing Peng , Antoine Lainé , Ka Chon Ng , Mutian Hua , Brett A. Helms , Miquel B. Salmeron , Cheng Wang

In the last years, optical readout of Micromegas gaseous detectors has been achieved by implementing a Micromegas detector on a glass anode coupled to a CMOS camera. Effective X-ray radiography was demonstrated using integrated imaging…