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In bacteria such as $\textit{Escherichia coli}$, DNA is compacted into a nucleoid near the cell center, while ribosomes$-$molecular complexes that translate messenger RNAs (mRNAs) into proteins$-$are mainly localized at the poles. We study…

Subcellular Processes · Quantitative Biology 2016-08-30 Michele Castellana , Sophia Hsin-Jung Li , Ned S. Wingreen

We studied the swimming of \textit{Escherichia coli} bacteria in the vicinity of the critical point in a solution of the non-ionic surfactant \chem{C_{12}E_{5}} in buffer solution. In phase contrast microscopy, each swimming cell produces a…

Soft Condensed Matter · Physics 2018-08-07 Nick Koumakis , Clémence Devailly , Wilson C. K. Poon

Optical tweezers are a versatile tool that can be used to manipulate small particles including both motile and non-motile bacteria and cells. The orientation of a non-spherical particle within a beam depends on the shape of the particle and…

Molecular communication is an expanding body of research. Recent advances in biology have encouraged using genetically engineered bacteria as the main component in the molecular communication. This has stimulated a new line of research that…

Information Theory · Computer Science 2012-09-13 Arash Einolghozati , Mohsen Sardari , Faramarz Fekr

When treated with antibiotics below the minimum inhibitory concentration, bacterial cell division turns off, but cell growth does not. Thus, rod-like bacteria, including E. coli, can elongate many times their length without increasing their…

Soft Condensed Matter · Physics 2026-03-11 Richard Z. DeCurtis , Yongtae Ahn , Jane E. Hill , Sara M. Hashmi

Motor proteins drive persistent motion and self-organisation of cytoskeletal filaments. However, state-of-the-art microscopy techniques and continuum modelling approaches focus on large length and time scales. Here, we perform…

Soft Condensed Matter · Physics 2024-06-03 Gerrit Vliegenthart , Arvind Ravichandran , Marisol Ripoll , Thorsten Auth , Gerhard Gompper

A physical scenario accounting for the existence of size-limited submicrometric domains in cell membranes is proposed. It is based on the numerical investigation of the counterpart, in lipidic membranes where proteins are diffusing, of the…

Soft Condensed Matter · Physics 2015-06-25 Nicolas Destainville

The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in…

Cell Behavior · Quantitative Biology 2016-06-29 Davide Ambrosi , Anna Zanzottera

In the present work we simulate the basic two-dimensional dynamics of swarming E. coli bacteria on the surface of a moderately soft agar plate. Individual bacteria are modelled by self-propelled ridged bodies (agents), which interact with…

Soft Condensed Matter · Physics 2016-12-31 David Hansmann , Guido Fier , Rubén Carlos Buceta

Centrifugation is a widespread laboratory technique used to separate mixtures into fractions characterized by a specific size, weight or density. We demonstrate that centrifugation can be also used to separate swimming cells having…

Soft Condensed Matter · Physics 2014-11-07 Claudio Maggi , Alessia Lepore , Jacopo Solari , Alessandro Rizzo , Roberto Di Leonardo

Understanding flow and transport of bacteria in porous media is crucial to technologies such as bioremediation, biomineralization or enhanced oil recovery. While physicochemical bacteria filtration is well-documented, recent studies showed…

Soft Condensed Matter · Physics 2022-08-24 Marco Dentz , Adama Creppy , Carine Douarche , Eric Clément , Harold Auradou

The self-organization of microbial ecosystems involves a large variety of mechanisms, ranging from biochemical signaling to population dynamics. Among these, the role of motility regulation has been little studied, despite the importance of…

Statistical Mechanics · Physics 2025-03-18 Alberto Dinelli , Ada Altieri , Julien Tailleur

Using analytical calculations and computer simulations we consider both the lateral diffusion of a membrane protein and the fluctuation spectrum of the membrane in which the protein is embedded. The membrane protein interacts with the…

Soft Condensed Matter · Physics 2015-05-18 Ellen Reister-Gottfried , Stefan M. Leitenberger , Udo Seifert

It has been argued that there is biological and modeling evidence that a non-linear diffusion coefficient of the type D(b) = D_0 b^{k} underlies the formation of a number of growth patterns of bacterial colonies. We study a…

Statistical Mechanics · Physics 2016-08-31 J. Mueller , W. van Saarloos

Biomolecular condensates are small droplets forming spontaneously in biological cells via phase separation. They play a role in many cellular processes, but it is unclear how cells control them. Cellular regulation often relies on…

Soft Condensed Matter · Physics 2024-03-15 Jan Kirschbaum , David Zwicker

Phase separation driven by nonequilibrium fluctuations is a hallmark of both living and synthetic active matter. Unlike equilibrium systems, where ordered states arise from the minimization of free energy, active systems are fueled by a…

The bacterium Escherichia coli (E. coli) moves in its natural environment in a series of straight runs, interrupted by tumbles which cause change of direction. It performs chemotaxis towards chemo-attractants by extending the duration of…

Quantitative Methods · Quantitative Biology 2010-07-12 Melissa Reneaux , Manoj Gopalakrishnan

Run-and-tumble is a common but vital strategy that bacteria employ to explore environment suffused with boundaries, as well as to escape from entrapment. In this study we reveal how this strategy and the resulting dynamical behavior can be…

Soft Condensed Matter · Physics 2025-01-30 Premkumar Leishangthem , Xuan Wang , Junan Chen , Shengqi Yang , Xinliang Xu

We investigate the oscillatory dynamics and bifurcation structure of a reaction-diffusion system with bistable nonlinearity and mass conservation, which was proposed by [Otsuji et al, PLoS Comp. Biol. 3 (2007), e108]. The system is a useful…

Cell Behavior · Quantitative Biology 2025-05-23 Masataka Kuwamura , Hirofumi Izuhara , Shin-ichiro Ei

Respiration in bacteria involves a sequence of energetically-coupled electron and proton transfers creating an electrochemical gradient of protons (a proton-motive force) across the inner bacterial membrane. With a simple kinetic model we…

Biological Physics · Physics 2015-05-13 Anatoly Yu. Smirnov , Sergey E. Savel'ev , Franco Nori
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