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Inspired by recent experiments on chromosomal dynamics, we introduce an exactly solvable model for the interaction between a flexible polymer and a set of motor-like enzymes. The enzymes can bind and unbind to specific sites of the polymer…

Soft Condensed Matter · Physics 2019-04-03 Stefanie Put , Takahiro Sakaue , Carlo Vanderzande

We study water between parallel metal walls under applied electric field accounting for the image effect at $T=298$ K. The electric field due to the surface charges serves to attract and orient nearby water molecules, while it tends to a…

Soft Condensed Matter · Physics 2015-07-24 Kyohei Takae , Akira Onuki

We investigate irreversibility and dissipation in single molecules that cooperatively fold/unfold in a two state manner under the action of mechanical force. We apply path thermodynamics to derive analytical expressions for the average…

Statistical Mechanics · Physics 2009-02-25 Maria Manosas , Alessandro Mossa , Nuria Forns , Josep Maria Huguet , Felix Ritort

Using coarse-grained molecular dynamics simulations, we analyze mechanically induced dissociation and unfolding of the protein complex CD48-2B4. This heterodimer is an indispensable component of the immunological system: 2B4 is a receptor…

Biomolecules · Quantitative Biology 2015-02-26 Bartosz Rozycki , Lukasz Mioduszewski , Marek Cieplak

We study the dynamical response of a harmonically trapped two-component few-fermion mixture to the external gaussian potential barrier moving across the system. The simultaneous role played by inter-particle interactions, rapidity of the…

Quantum Gases · Physics 2021-05-26 Dillip K. Nandy , Tomasz Sowiński

Unstructured proteins can modulate cellular responses to environmental conditions by undergoing coil-globule transitions and phase separation. However, the molecular mechanisms of these phenomena still need to be fully understood. Here, we…

Soft Condensed Matter · Physics 2023-06-28 Bernat Durà Faulí , Valentino Bianco , Giancarlo Franzese

We investigate the constitutive response of two-dimensional packed samples of polygons using molecular dynamics simulation. The incremental elasto-plastic response is examined in the pre-failure regime. Besides the Young modulus and the…

Condensed Matter · Physics 2007-05-23 F. Alonso-Marroquin , H. J. Herrmann , S. Luding

Motivated by rolling adhesion of white blood cells in the vasculature, we study how cells move in linear shear flow above a wall to which they can adhere via specific receptor-ligand bonds. Our computer simulations are based on a Langevin…

Cell Behavior · Quantitative Biology 2008-04-30 C. B. Korn , U. S. Schwarz

We study numerically the phase diagram and the response under a driving force of the phase field crystal model for pinned lattice systems introduced recently for both one and two dimensional systems. The model describes the lattice system…

Materials Science · Physics 2009-09-30 C. V. Achim , J. A. P. Ramos , M. Karttunen , K. R. Elder , E. Granato , T. Ala-Nissila , S. C. Ying

The dielectric behavior of a linear cluster of two or more living cells connected by tight junctions is analyzed using a spectral method. The polarizability of this system is obtained as an expansion over the eigenmodes of the linear…

Biological Physics · Physics 2010-02-12 Titus Sandu , Daniel Vrinceanu , Eugen Gheorghiu

Models of adhesion of extended particles on linear and planar substrates are of interest in interpreting surface deposition in colloid, polymer, and certain biological systems. An introduction is presented to recent theoretical advances in…

Condensed Matter · Physics 2016-11-03 Vladimir Privman

Pulsating behavior is a universal phenomenon in versatile fields. In nonlinear dissipative systems, the solitons could also pulsate under proper conditions and show many interesting dynamics. However, the pulsation dynamics is generally…

Understanding contact line dynamics on superhydrophobic surfaces with microscopic structures is essential for designing materials with reduced drag, anti-icing, self-cleaning, and anti-fouling properties. Using numerical simulations, we…

Fluid Dynamics · Physics 2025-11-27 Pawan Kumar , Marta Krasowska , Joseph D. Berry

Quantifying the response of marine mussel plaque attachment on wet surfaces remains a significant challenge to a mechanistic understanding of plaque adhesion. Here, we developed a customised microscopy system combined with two-dimensional…

Biological Physics · Physics 2024-07-02 Yong Pang , Tao Liu

Adhesion plays an integral role in diverse biological functions ranging from cellular transport to tissue development. Estimation of adhesion strength, therefore, becomes important to gain biophysical insight into these phenomena. In this…

Biological Physics · Physics 2016-05-02 Ehsan Irajizad , Ashutosh Agrawal

We present a novel method to investigate the dynamics of a single semiflexible polymer, subject to anisotropic friction in a viscous fluid. In contrast to previous approaches, we do not rely on a discrete bead-rod model, but introduce a…

Biomolecules · Quantitative Biology 2009-11-13 Tobias Munk , Oskar Hallatschek , Chris H. Wiggins , Erwin Frey

The scalar modes of the geometry induced by dimensional decoupling are investigated. In the context of the low energy string effective action, solutions can be found where the spatial part of the background geometry is the direct product of…

High Energy Physics - Theory · Physics 2009-11-11 Massimo Giovannini

The development of traction-force microscopy, in the past two decades, has created the unprecedented opportunity of performing direct mechanical measurements on living cells as they adhere or crawl on uniform or micro-patterned substrates.…

Biological Physics · Physics 2019-10-25 Luca Giomi

The interplay between structure and dynamics in non-equilibrium steady-state is far from understood. We address this interplay by tracking Brownian Dynamics trajectories of particles in a binary colloid of opposite charges in an external…

Soft Condensed Matter · Physics 2016-12-08 Suman Dutta , J. Chakrabarti

The exciton dissociation and charge separation occurring on subpicosecond time scales following the photoexcitation are studied in a model donor/acceptor heterojunction using a fully quantum approach. Higher-than-LUMO acceptor orbitals…

Chemical Physics · Physics 2017-09-18 Veljko Janković , Nenad Vukmirović