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Related papers: The Problems of Ageing

200 papers

It is now increasingly realized that the underlying mechanism which governs aging (ageing) is a complex interplay of genetic regulation and damage-accumulation. "Aging as a result of accumulation of 'faults' on cellular and molecular…

Tissues and Organs · Quantitative Biology 2011-03-31 Jicun Wang , Thomas Michelitsch , Arne Wunderlin , Ravi Mahadeva

Many recent experiments probed the off equilibrium dynamics of spin glasses and other glassy systems through temperature cycling protocols and observed memory and rejuvenation phenomena. Here we show through numerical simulations, using…

Disordered Systems and Neural Networks · Physics 2009-09-29 Florent Krzakala , Federico Ricci-Tersenghi

The spin glasses are disordered and frustrated magnetic systems. They show aging phenomena which are also a characteristic feature of structural glasses, polymers, dielectrics, colloids, etc. Under a strong enough magnetic field variation,…

Disordered Systems and Neural Networks · Physics 2007-05-23 V. Dupuis , E. Vincent , F. Bert , D. Herisson , J. Hammann , M. Ocio

I consider selected (most important according to my own choice) unsolved problems in particle theory, both those related to extensions of the Standard Model (neutrino oscillations, which probably do not fit the usual three-generation…

High Energy Physics - Phenomenology · Physics 2015-06-03 Sergey Troitsky

Accurate stellar ages remain one of the most poorly constrained, but most desired, astronomical quantities. Here we briefly summarize some recent efforts to improve the stellar age scale from a subset of talks from the ``Stellar Ages''…

We introduce a set of theoretical ideas that form the basis for an analytical framework capable of describing nonequilibrium dynamics in glassy systems. We test the resulting scenario by comparing its predictions with numerical simulations…

Statistical Mechanics · Physics 2009-11-07 Horacio E. Castillo , Claudio Chamon , Leticia F. Cugliandolo , Malcolm P. Kennett

In this paper, we introduce some new notions of aging based on geometric, harmonic means of failure rate and aging intensity function. We define a generalized version of aging functions called specific interval-average geometric hazard…

Statistics Theory · Mathematics 2024-07-02 Subarna Bhattacharjee , Ananda Sen , Sabana Anwar , Aninda Kumar Nanda

The mortality rate of many complex multicellular organisms increase with age, which suggests that net aging damage is accumulative, despite remodeling processes. But how exactly do little mishaps in the cellular level accumulate and spread…

Tissues and Organs · Quantitative Biology 2017-12-12 Daniel Suma , Aylin Acun , Pinar Zorlutuna , Dervis Can Vural

Aging associated brain decline often result in some kind of dementia. Even when this is a complex brain disorder a physical model can be used in order to describe its general behavior. This model is based in first principles. A…

Neurons and Cognition · Quantitative Biology 2016-07-22 Oscar Sotolongo-Costa , L. M. Gaggero-Sager , J. T. Becker , F. Maestú , O. Sotolongo-Grau

I review the challenges and problems facing the standard cosmological model, involving an $\Omega=1$ Universe dominated by non-baryonic dark matter, which arise due to: age estimates of the universe, estimates of the baryon fraction of the…

Astrophysics · Physics 2007-05-23 Lawrence M. Krauss

We present a one dimensional model for diffusion on a hierarchical tree structure. It is shown that this model exhibits aging phenomena although no disorder is present. The origin of aging in this model is therefore the hierarchical…

Disordered Systems and Neural Networks · Physics 2009-10-30 U. Geppert , H. Rieger , M. Schreckenberg

Disordered solids often change their elastic response as they slowly age. Using experiments and simulations, we study how aging disordered planar networks under an applied stress affects their nonlinear elastic response. We are able to…

Soft Condensed Matter · Physics 2020-11-18 Daniel Hexner , Nidhi Pashine , Andrea J. Liu , Sidney R. Nagel

The accumulation of somatic mutations is a driver of cancer and has long been associated with ageing. Due to limitations in quantifying mutation burden with age in non-cancerous tissues, the impact of somatic mutations in other ageing…

Genomics · Quantitative Biology 2023-07-31 Kasit Chatsirisupachai , João Pedro de Magalhães

Astrophysical observations provide a picture of the universe as a 4-dim homogeneous and isotropic flat space-time dominated by an unknown form of dark energy. To achieve such a cosmology one has to consider in the early universe an…

Astrophysics · Physics 2009-11-10 F. Canfora , A. Troisi

Multitime correlation functions provide useful probes for the ensembles of trajectories underlying the stochastic dynamics of complex systems. These can be obtained by measuring their optical response to sequences of ultrashort optical…

Soft Condensed Matter · Physics 2009-11-13 Frantisek Sanda , Shaul Mukamel

The distribution of a population throughout the physiological age of the individuals is very relevant information in population studies. It has been modeled by the Langevin and the Fokker- Planck equations. A major problem with these…

Biological Physics · Physics 2017-07-19 Bernardo A. Mello

This paper outlines astrophysical issues related to the long term fate of the universe. We consider the evolution of planets, stars, stellar populations, galaxies, and the universe itself over time scales which greatly exceed the current…

Astrophysics · Physics 2008-11-26 Fred C. Adams , Gregory Laughlin

The aging effects of a 'diffusing glass', a single elastic string diffusing in a two-dimensional disordered media assisted by thermal noise are studied by Monte Carlo (MC) simulations. We find for the first time convincing numerical…

Disordered Systems and Neural Networks · Physics 2009-10-31 Hajime Yoshino

Age spots are the brown spots that develop in the skin but change in color and shape with time. To understand the mechanism of development of age spots, characteristics of age spots are analyzed by Misrepair mechanism, a mechanism…

Tissues and Organs · Quantitative Biology 2018-02-06 Jicun Wang-Michelitsch , Thomas M Michelitsch

In these lecture notes I describe some of the main theoretical ideas emerged to explain the aging dynamics. This is meant to be a very short introduction to aging dynamics and no previous knowledge is assumed. I will go through simple…

Statistical Mechanics · Physics 2009-11-11 Giulio Biroli