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X-ray 3D tomography is So far limited to micron resolution because of the large focusing spot of the focused electron beam on the metal target. Here, we proposed a nanofocous X-ray 3D tomography system based on focused electrons from…

Instrumentation and Detectors · Physics 2018-03-14 Gholamreza Shayeganrad

Recently CMOS (complementary metal-oxide semiconductor) sensors have progressed to a point where they may offer improved performance in imaging x-ray detection compared to the CCDs often used in x-ray satellites. We demonstrate x-ray…

Instrumentation and Detectors · Physics 2020-12-23 Steve Tammes , Tyler Roth , Philip Kaaret , Casey DeRoo , Abdallah Elmaleh , Jessica L McChesney , Fanny Rodolakis

A well-known diagnostic imaging modality, termed ultrasound tomography, was quickly developed for the detection of very small tumors whose sizes are smaller than the wavelength of the incident pressure wave without ionizing radiation,…

Medical Physics · Physics 2015-08-05 Tran Quang-Huy , Tran Duc-Tan , Huynh Huu Tue , Nguyen Linh-Trung

Cosmic ray muon has strong penetrating power and no ionizing radiation hazards, which makes it an ideal probe for detecting special nuclear materials. In this paper, a high spatial resolution muon tomography system based on Micromegas…

Instrumentation and Detectors · Physics 2022-02-16 Yu Wang , Zhiyong Zhang , Shubin Liu , Zhongtao Shen , Changqing Feng , Jianguo Liu , Yulin Liu

Histological visualizations are critical to clinical disease management and are fundamental to biological understanding. However, current approaches that rely on bright-field microscopy require extensive tissue preparation prior to imaging.…

The increasingly demand for machining accuracy and product quality excites a great interest in high-resolution non-destructive testing (NDT) methods, but spatial resolution of conventional high-energy computed tomography (CT) is limited to…

A novel method and experimental configuration are proposed that allow the collection of high-quality X-ray absorption spectroscopy (XAS) data in transmission mode on a standard laboratory diffractometer. This configuration makes use of…

Instrumentation and Detectors · Physics 2025-09-23 Milen Gateshki , Charalampos Zarkadas , Detlef Beckers

This Letter reports a demonstration of off-axis compressed holography in low-light level imaging conditions. An acquisition protocol relying on a single exposure of a randomly undersampled diffraction map of the optical field, recorded in…

Optics · Physics 2015-05-27 Marcio M. Marim , Elsa Angelini , J. C. Olivo-Marin , Michael Atlan

Breast cancer is the most frequently diagnosed human cancer in the United States at present. Early detection is crucial for its successful treatment. X-ray mammography and digital breast tomosynthesis are currently the main methods for…

In this work, image analysis techniques used in astrophysics to detect low-contrast signals have been adapted in the processing of Computed Tomography (CT) images, combining Centroidal Voronoi Tessellation (CVT) and machine learning…

Medical Physics · Physics 2025-03-11 Lorenzo Lasagni

Ptychography is an enabling coherent diffraction imaging technique for both fundamental and applied sciences. Its applications in optical microscopy, however, fall short for its low imaging throughput and limited resolution. Here, we report…

Holotomography, a three-dimensional quantitative phase imaging technique, presents an innovative, non-invasive approach to studying biological samples by exploiting the refractive index as an intrinsic imaging contrast. Despite offering…

Optics · Physics 2023-08-04 Herve Hugonnet , HyunJun Han , Weisun Park , YongKeun Park

We present a novel way of wavefront sensing using a commercially available, continuous-wave time-of-flight camera with QVGA-resolution. This CMOS phase camera is capable of sensing externally modulated light sources with frequencies up to…

Instrumentation and Detectors · Physics 2021-08-18 Erik Muñiz , Varun Srivastava , Subham Vidyant , Stefan W. Ballmer

A cluster imaging technique for Transmission Electron Microscopy with a direct detection CMOS pixel sensor is presented. Charge centre-of-gravity reconstruction for individual electron clusters improves the spatial resolution and thus the…

Instrumentation and Detectors · Physics 2009-10-29 Marco Battaglia , Devis Contarato , Peter Denes , Piero Giubilato

We report a novel lensless on-chip microscopy platform based on near-field blind ptychographic modulation. In this platform, we place a thin diffuser in between the object and the image sensor for light wave modulation. By blindly scanning…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Shaowei Jiang , Jiakai Zhu , Pengming Song , Chengfei Guo , Zichao Bian , Ruihai Wang , Yikun Huang , Shiyao Wang , He Zhang , Guoan Zheng

An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing detection architecture. A wide range of photoacoustic…

Biological Physics · Physics 2021-08-04 Kevan Bell , Lyazzat Mukhangaliyeva , Layla Khalili , Parsin Haji Reza

Chip-based optical frequency combs address the demand for compact, bright, coherent light sources of equidistant phase-locked lines. Traditionally, the Fourier Transform Spectroscopy (FTS) technique has been considered a suboptimal choice…

Optics · Physics 2024-03-05 Lukasz A. Sterczewski , Mahmood Bagheri

Fabrication of X-ray gratings has surged in the last two decades thanks to their vast employment in X-ray Phase Contrast Imaging, an imaging technique able to boost X-ray sensitivity to detect otherwise invisible details. These high aspect…

Photography usually requires optics in conjunction with a recording device (an image sensor). Eliminating the optics could lead to new form factors for cameras. Here, we report a simple demonstration of imaging using a bare CMOS sensor that…

Computer Vision and Pattern Recognition · Computer Science 2018-05-23 Ganghun Kim , Kyle Isaacson , Racheal Palmer , Rajesh Menon

Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan