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Building effective clinical decision support systems requires the synthesis of complex heterogeneous multimodal data. Such modalities include temporal electronic health records data, medical images, radiology reports, and clinical notes.…

Artificial Intelligence · Computer Science 2026-05-12 Baraa Al Jorf , Farah E. Shamout

To protect patient safety, modern pharmaceutical complexity demands strict prescription verification. We offer a new approach - Rx Strategist - that makes use of knowledge graphs and different search strategies to enhance the power of Large…

Computation and Language · Computer Science 2024-09-06 Phuc Phan Van , Dat Nguyen Minh , An Dinh Ngoc , Huy Phan Thanh

Emergency departments worldwide face rising patient volumes, workforce shortages, and variability in triage decisions that threaten the delivery of timely and accurate care. Current triage methods rely primarily on vital signs, routine…

Quantitative Methods · Quantitative Biology 2025-10-21 Kerem Delikoyun , Qianyu Chen , Win Sen Kuan , John Tshon Yit Soong , Matthew Edward Cove , Oliver Hayden

Advancements in large language models (LLMs) allow them to address diverse questions using human-like interfaces. Still, limitations in their training prevent them from answering accurately in scenarios that could benefit from multiple…

Artificial Intelligence · Computer Science 2025-04-09 Yoshitaka Inoue , Tianci Song , Xinling Wang , Augustin Luna , Tianfan Fu

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical ideas into robust implementations in the highly specialized…

Machine Learning · Computer Science 2025-03-06 Sizhe Liu , Yizhou Lu , Siyu Chen , Xiyang Hu , Jieyu Zhao , Yingzhou Lu , Yue Zhao

Large Language Model (LLM)-based recommendation systems have demonstrated remarkable capabilities in understanding user preferences and generating personalized suggestions. However, existing approaches face critical challenges in…

Information Retrieval · Computer Science 2026-04-24 Sushant Mehta

LLM-based agents have gained considerable attention for their decision-making skills and ability to handle complex tasks. Recognizing the current gap in leveraging agent capabilities for multi-agent collaboration in recommendation systems,…

Information Retrieval · Computer Science 2024-11-04 Zhefan Wang , Yuanqing Yu , Wendi Zheng , Weizhi Ma , Min Zhang

Recent attempts to integrate large language models (LLMs) into recommender systems have gained momentum, but most remain limited to simple text generation or static prompt-based inference, failing to capture the complexity of user…

Information Retrieval · Computer Science 2025-10-16 Jiin Park , Misuk Kim

Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains limited due to the lack of real world datasets, constrained…

Artificial Intelligence · Computer Science 2025-11-07 Jiahao Zhao , Luxin Xu , Minghuan Tan , Lichao Zhang , Ahmadreza Argha , Hamid Alinejad-Rokny , Min Yang

Multi-Modal Large Language Models (MLLMs), despite being successful, exhibit limited generality and often fall short when compared to specialized models. Recently, LLM-based agents have been developed to address these challenges by…

Computation and Language · Computer Science 2024-10-08 Binxu Li , Tiankai Yan , Yuanting Pan , Jie Luo , Ruiyang Ji , Jiayuan Ding , Zhe Xu , Shilong Liu , Haoyu Dong , Zihao Lin , Yixin Wang

Medical Large Vision-Language Models (Med-LVLMs) have been widely adopted for medical report generation. Despite Med-LVLMs producing state-of-the-art performance, they exhibit a bias toward predicting all findings as normal, leading to…

Multiagent Systems · Computer Science 2025-05-27 Pengyu Wang , Shuchang Ye , Usman Naseem , Jinman Kim

The rise of LLM-based agents shows great potential to revolutionize task planning, capturing significant attention. Given that these agents will be integrated into high-stake domains, ensuring their reliability and safety is crucial. This…

Computation and Language · Computer Science 2024-10-07 Wenyue Hua , Xianjun Yang , Mingyu Jin , Zelong Li , Wei Cheng , Ruixiang Tang , Yongfeng Zhang

Therapy recommendation for chronic patients with multimorbidity is challenging due to risks of treatment conflicts. Existing decision support systems face scalability limitations. Inspired by the way in which general practitioners (GP)…

Artificial Intelligence · Computer Science 2025-07-16 Yicong Wu , Ting Chen , Irit Hochberg , Zhoujian Sun , Ruth Edry , Zhengxing Huang , Mor Peleg

Large Language Models (LLMs) achieve competitive results compared to human experts in medical examinations. However, it remains a challenge to apply LLMs to complex clinical decision-making, which requires a deep understanding of medical…

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

The acquisition of agentic capabilities has transformed LLMs from "knowledge providers" to "action executors", a trend that while expanding LLMs' capability boundaries, significantly increases their susceptibility to malicious use. Previous…

Cryptography and Security · Computer Science 2025-05-30 Jinchuan Zhang , Lu Yin , Yan Zhou , Songlin Hu

The rapid evolution of sophisticated cyberattacks has strained modern Security Operations Centers (SOC), which traditionally rely on rule-based or signature-driven detection systems. These legacy frameworks often generate high volumes of…

Cryptography and Security · Computer Science 2026-03-03 Chuanming Tang , Ling Qing , Shifeng Chen

The rapid advancement of large language model (LLM) agents has raised new concerns regarding their safety and security. In this paper, we propose GuardAgent, the first guardrail agent to protect target agents by dynamically checking whether…

Machine Learning · Computer Science 2025-05-30 Zhen Xiang , Linzhi Zheng , Yanjie Li , Junyuan Hong , Qinbin Li , Han Xie , Jiawei Zhang , Zidi Xiong , Chulin Xie , Carl Yang , Dawn Song , Bo Li

Interactive conversational recommender systems have gained significant attention for their ability to capture user preferences through natural language interactions. However, existing approaches face substantial challenges in handling…

Artificial Intelligence · Computer Science 2025-10-03 Bo Ma , Hang Li , ZeHua Hu , XiaoFan Gui , LuYao Liu , Simon Lau

The discovery of novel small molecule drugs remains a critical scientific challenge with far-reaching implications for treating diseases and advancing human health. Traditional drug development--especially for small molecule…

Biomolecules · Quantitative Biology 2025-04-01 Bowen Gao , Yanwen Huang , Yiqiao Liu , Wenxuan Xie , Wei-Ying Ma , Ya-Qin Zhang , Yanyan Lan
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