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Visual Language Models (VLMs) achieve promising results in medical reasoning but struggle with hallucinations, vague descriptions, inconsistent logic and poor localization. To address this, we propose a agent framework named Medical Visual…

Artificial Intelligence · Computer Science 2025-10-22 Guangfu Guo , Xiaoqian Lu , Yue Feng

Visual compliance verification is a critical yet underexplored problem in computer vision, especially in domains such as media, entertainment, and advertising where content must adhere to complex and evolving policy rules. Existing methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Rahul Ghosh , Baishali Chaudhury , Hari Prasanna Das , Meghana Ashok , Ryan Razkenari , Long Chen , Sungmin Hong , Chun-Hao Liu

To address the limitations of Large Language Models (LLMs) in the International Classification of Diseases (ICD) coding task, where they often produce inaccurate and incomplete prediction results due to the high-dimensional and skewed…

Computation and Language · Computer Science 2024-08-15 Rumeng Li , Xun Wang , Hong Yu

Modern clinical practice relies on evidence-based guidelines implemented as compact scoring systems composed of a small number of interpretable decision rules. While machine-learning models achieve strong performance, many fail to translate…

Machine Learning · Computer Science 2026-05-25 Silas Ruhrberg Estévez , Christopher Chiu , Mihaela van der Schaar

Lipid nanoparticles (LNPs) are among the most clinically mature platforms for nucleic acid delivery, yet designing lipids that are both effective and biologically safe remains a major bottleneck. In practical screening, toxicity is a…

Artificial Intelligence · Computer Science 2026-05-26 Leshu Li , An Lu , Haiyu Wang , Zhibin Feng , Conghui Duan , Qing Bao , Zongmin Zhao , Sai Qian Zhang

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Answering complex medical questions requires not only domain expertise and patient-specific information, but also structured and multi-perspective reasoning. Existing multi-agent approaches often rely on fixed roles or shallow interaction…

Artificial Intelligence · Computer Science 2026-03-04 Siqi Ma , Jiajie Huang , Fan Zhang , Yue Shen , Jinlin Wu , Guohui Fan , Zhu Zhang , Zelin Zang

LLM-based agents have demonstrated strong potential for autonomous machine learning, yet their applicability to health data remains limited. Existing systems often struggle to generalize across heterogeneous health data modalities, rely…

Artificial Intelligence · Computer Science 2026-02-03 Tong Xia , Weibin Li , Gang Liu , Yong Li

Rare diseases, despite their low individual incidence, collectively impact around 300 million people worldwide due to the vast number of diseases. The involvement of multiple organs and systems, and the shortage of specialized doctors with…

Computation and Language · Computer Science 2025-11-11 Xuanzhong Chen , Ye Jin , Xiaohao Mao , Lun Wang , Shuyang Zhang , Ting Chen

User profile embedded in the prompt template of personalized recommendation agents play a crucial role in shaping their decision-making process. High-quality user profiles are essential for aligning agent behavior with real user interests.…

Information Retrieval · Computer Science 2025-05-27 Yunxiao Shi , Wujiang Xu , Zeqi Zhang , Xing Zi , Qiang Wu , Min Xu

Formulating a treatment plan is inherently a complex reasoning and refinement task rather than a simple generation problem. However, existing large language models (LLMs) mainly rely on one-shot output without explicit verification, which…

Artificial Intelligence · Computer Science 2026-05-08 Junkai Li , Yunghwei Lai , Tianyi Zhu , Zheng Long Lee , Weizhi Ma , Yang Liu

Motivated by the challenge to improve the adversarial robustness, security, and trust of medical decision making intelligent agents, this study develops a full-link security enhancement framework, which describes "input risk perception -…

Cryptography and Security · Computer Science 2026-05-12 Saisai Hu

Large language model (LLM) agents are vulnerable to prompt-injection attacks that propagate through multi-step workflows, tool interactions, and persistent context, making input-output filtering alone insufficient for reliable protection.…

Artificial Intelligence · Computer Science 2026-04-21 Hailin Liu , Eugene Ilyushin , Jie Ni , Min Zhu

PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond,…

Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…

Artificial Intelligence · Computer Science 2025-10-14 Hongjie Zheng , Zesheng Shi , Ping Yi

Drug discovery is a complex, multi-step pipeline that remains heavily dependent on manual, experience-driven operations; meanwhile, existing customized artificial intelligence tools are fragmented across web applications, desktop software,…

Biomolecules · Quantitative Biology 2026-03-03 Qihua Pan , Dong Xu , Qianwei Yang , Jenna Xinyi Yao , Sisi Yuan , Zexuan Zhu , Jianqiang Li , Junkai Ji

Code generation models based on large language models (LLMs) have gained wide adoption, but challenges remain in ensuring safety, accuracy, and controllability, especially for complex tasks. Existing methods often lack dynamic integration…

Software Engineering · Computer Science 2025-10-13 Aofan Liu , Haoxuan Li , Bin Wang , Ao Yang , Hui Li

Hit identification is a central challenge in early drug discovery, traditionally requiring substantial experimental resources. Recent advances in artificial intelligence, particularly large language models (LLMs), have enabled virtual…

Recommendation systems must optimize multiple objectives while satisfying hard business constraints such as fairness and coverage. For example, an e-commerce platform may require every recommendation list to include items from multiple…

Information Retrieval · Computer Science 2026-02-04 Guilin Zhang , Kai Zhao , Jeffrey Friedman , Xu Chu

Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling. We propose a multi-agent medical QA…

Computation and Language · Computer Science 2026-02-17 Naeimeh Nourmohammadi , Md Meem Hossain , The Anh Han , Safina Showkat Ara , Zia Ush Shamszaman