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The extraordinary advancements in neuroscientific technology for brain recordings over the last decades have led to increasingly complex spatio-temporal datasets. To reduce oversimplifications, new models have been developed to be able to…

Methodology · Statistics 2020-09-22 Nicolo' Margaritella , Vanda Inacio , Ruth King

Functional data analysis (FDA) deals with high-resolution data recorded over a continuum, such as time, space or frequency. Device-based assessments of physical activity or sleep are objective yet still prone to measurement error. We…

Dynamic prediction, which typically refers to the prediction of future outcomes using historical records, is often of interest in biomedical research. For datasets with large sample sizes, high measurement density, and complex correlation…

Methodology · Statistics 2024-12-04 Ying Jin , Andrew Leroux

Background and Objectives: This paper focuses on using AI to assess the cognitive function of older adults with mild cognitive impairment or mild dementia using physiological data provided by a wearable device. Cognitive screening tools are…

Neurons and Cognition · Quantitative Biology 2025-11-10 Assma Habadi , Milos Zefran , Lijuan Yin , Woojin Song , Maria Caceres , Elise Hu , Naoko Muramatsu

Chronic pain is a global health challenge affecting millions of individuals, making it essential for physicians to have reliable and objective methods to measure the functional impact of clinical treatments. Traditionally used methods, like…

Machine Learning · Computer Science 2026-03-23 Yuanheng Mao , Lillian Yang , Stephen Yang , Ethan Shao , Zihan Li

The ability to order outcomes is necessary to make comparisons which is complicated when there is no natural ordering on the space of outcomes, as in the case of functional outcomes. This paper examines methods for extracting a scalar…

Methodology · Statistics 2024-02-06 Lanqiu Yao , Thaddeus Tarpey

In many phenomena, data are collected on a large scale and of different frequencies. In this context, functional data analysis (FDA) has become an important statistical methodology for analyzing and modeling such data. The approach of FDA…

Methodology · Statistics 2022-04-11 Israel Martínez-Hernández , Marc G. Genton

We propose a novel algorithm - Multifractal Cross-Correlation Analysis (MFCCA) - that constitutes a consistent extension of the Detrended Cross-Correlation Analysis (DCCA) and is able to properly identify and quantify subtle characteristics…

Data Analysis, Statistics and Probability · Physics 2014-02-25 Paweł Oświȩcimka , Stanisław Drożdż , Marcin Forczek , Stanisław Jadach , Jarosław Kwapień

Recent advances in data analytics and computer-aided diagnostics stimulate the vision of patient-centric precision healthcare, where treatment plans are customized based on the health records and needs of every patient. In physical…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Yalin Liao , Aleksandar Vakanski , Min Xian , David Paul , Russell Baker

The advance of modern sensor technologies enables collection of multi-stream longitudinal data where multiple signals from different units are collected in real-time. In this article, we present a non-parametric approach to predict the…

Machine Learning · Statistics 2023-07-04 Seokhyun Chung , Raed Kontar

In this paper, we introduce a new extension of the Singular Spectrum Analysis (SSA) called functional SSA to analyze functional time series. The new methodology is developed by integrating ideas from functional data analysis and univariate…

Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However,…

Neurons and Cognition · Quantitative Biology 2018-11-16 Patrick Schwab , Walter Karlen

With today's technological advancements, mobile phones and wearable devices have become extensions of an increasingly diffused and smart digital infrastructure. In this paper, we examine mobile health (mHealth) platforms and their health…

General Economics · Economics 2021-02-18 Anindya Ghose , Xitong Guo , Beibei Li , Yuanyuan Dang

Estimation and inference with modern longitudinal data from wearable devices, which consist of biological signals at high-frequency time points, is burdened by massive computational costs. We propose a distributed estimation and inference…

Methodology · Statistics 2023-09-13 Cole Manschot , Emily C. Hector

Functional Principal Component Analysis (FPCA) has become a widely-used dimension reduction tool for functional data analysis. When additional covariates are available, existing FPCA models integrate them either in the mean function or in…

Methodology · Statistics 2022-04-13 Ci-Ren Jiang , Eardi Lila , John AD Aston , Jane-Ling Wang

Test data measured by medical instruments often carry imprecise ranges that include the true values. The latter are not obtainable in virtually all cases. Most learning algorithms, however, carry out arithmetical calculations that are…

Machine Learning · Computer Science 2020-07-27 Mei Wang , Jianwen Su , Haiqin Lu

Sensor signals acquired in the industrial process contain rich information which can be analyzed to facilitate effective monitoring of the process, early detection of system anomalies, quick diagnosis of fault root causes, and intelligent…

Signal Processing · Electrical Eng. & Systems 2020-05-27 Feng Ye , Zhijie Xia , Min Dai , Zhisheng Zhang

Electronic health records (EHRs) provide a powerful basis for predicting the onset of health outcomes. Yet EHRs primarily capture in-clinic events and miss aspects of daily behavior and lifestyle containing rich health information. Consumer…

We propose a new fast generalized functional principal components analysis (fast-GFPCA) algorithm for dimension reduction of non-Gaussian functional data. The method consists of: (1) binning the data within the functional domain; (2)…

Methodology · Statistics 2023-06-06 Andrew Leroux , Ciprian Crainiceanu , Julia Wrobel

Most statistical process control programmes in healthcare focus on surveillance of outcomes at the final stage of a procedure, such as mortality or failure rates. Such an approach ignores the multi-stage nature of these procedures, in which…

Methodology · Statistics 2020-06-29 Doaa Ayad , Nokuthaba Sibanda