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At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

Machine Learning · Computer Science 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

In healthcare prediction tasks, it is essential to exploit the correlations between medical features and learn better patient health representations. Existing methods try to estimate feature correlations only from data, or increase the…

Machine Learning · Computer Science 2022-05-24 Xinyu Ma , Xu Chu , Yasha Wang , Hailong Yu , Liantao Ma , Wen Tang , Junfeng Zhao

This paper is motivated by modeling the cycle-to-cycle variability associated with the resistive switching operation behind memristors. As the data are by nature curves, functional principal component analysis is a suitable candidate to…

Statistics Theory · Mathematics 2024-11-20 C. Acal , A. M. Aguilera , F. J. Alonso , J. E. Ruiz-Castro , J. B. Roldán

Functional principal component analysis (FPCA) is an important technique for dimension reduction in functional data analysis (FDA). Classical FPCA method is based on the Karhunen-Lo\`{e}ve expansion, which assumes a linear structure of the…

Methodology · Statistics 2023-06-27 Rou Zhong , Chunming Zhang , Jingxiao Zhang

Objective: The aim of this study is to develop a smartphone-based high-frequency remote monitoring platform, assess its feasibility for remote monitoring of symptoms in Parkinson's disease, and demonstrate the value of data collected using…

Computers and Society · Computer Science 2016-01-06 Andong Zhan , Max A. Little , Denzil A. Harris , Solomon O. Abiola , E. Ray Dorsey , Suchi Saria , Andreas Terzis

Computational mental health research develops models to predict and understand psychological phenomena, but often relies on inappropriate measures of psychopathology constructs, undermining validity. We identify three key issues: (1)…

Human-Computer Interaction · Computer Science 2025-04-22 Chen Shani , Elizabeth C. Stade

Multilinear Principal Component Analysis (MPCA) is a widely utilized method for the dimension reduction of tensor data. However, the integration of MPCA into federated learning remains unexplored in existing research. To tackle this gap,…

Machine Learning · Computer Science 2024-04-30 Chengyu Zhou , Yuqi Su , Tangbin Xia , Xiaolei Fang

This paper establishes the functional average as an important estimand for causal inference. The significance of the estimand lies in its robustness against traditional issues of confounding. We prove that this robustness holds even when…

Statistics Theory · Mathematics 2023-12-04 Shane Sparkes , Erika Garcia , Lu Zhang

Multimodal evidence is critical in computational pathology: gigapixel whole slide images capture tumor morphology, while patient-level clinical descriptors preserve complementary context for prognosis. Integrating such heterogeneous signals…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Chengying She , Chengwei Chen , Xinran Zhang , Ben Wang , Lizhuang Liu , Chengwei Shao , Yun Bian

Physical activity during hip fracture rehabilitation is essential for mitigating long-term functional decline in geriatric patients. However, it is rarely quantified in clinical practice. Existing continuous monitoring systems with…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Shuhao Que , Dieuwke van Dartel , Ilse Heeringa , Han Hegeman , Miriam Vollenbroek-Hutten , Ying Wang

Multivariate functional data from a complex system are naturally high-dimensional and have complex cross-correlation structure. The complexity of data structure can be observed as that (1) some functions are strongly correlated with similar…

Machine Learning · Statistics 2018-04-12 Chen Zhang , Hao Yan , Seungho Lee , Jianjun Shi

Real-world clinical data is inherently multimodal, providing complementary evidence that mirrors the practical necessity of jointly assessing multiple related outcomes. Although multi-task learning can improve efficiency by sharing…

Machine Learning · Computer Science 2026-05-06 He Lyu , Huolin Zeng , Junren Wang , Huazhen Yang , Linchao He , Yong Chen , Zhirui Li , Andreas Maier , Siming Bayer , Huan Song

Machine learning (ML) models trained on subjective self-report scores struggle to objectively classify pain accurately due to the significant variance between real-time pain experiences and recorded scores afterwards. This study developed…

Machine Learning · Computer Science 2023-08-03 Boluwatife E. Faremi , Jonathon Stavres , Nuno Oliveira , Zhaoxian Zhou , Andrew H. Sung

Functional data analysis (FDA) is a part of modern multivariate statistics that analyses data providing information about curves, surfaces or anything else varying over a certain continuum. In economics and empirical finance we often have…

Methodology · Statistics 2019-10-25 Daniel Kosiorowski , Jerzy P. Rydlewski , Małgorzata Snarska

To date, research on sensor-equipped mobile devices has primarily focused on the purely supervised task of human activity recognition (walking, running, etc), demonstrating limited success in inferring high-level health outcomes from…

Machine Learning · Computer Science 2020-11-10 Dimitris Spathis , Ignacio Perez-Pozuelo , Soren Brage , Nicholas J. Wareham , Cecilia Mascolo

Multimodal electronic health record (EHR) data can offer a holistic assessment of a patient's health status, supporting various predictive healthcare tasks. Recently, several studies have embraced the multitask learning approach in the…

Machine Learning · Computer Science 2024-06-19 Muhao Xu , Zhenfeng Zhu , Youru Li , Shuai Zheng , Yawei Zhao , Kunlun He , Yao Zhao

Functional mixed models are widely useful for regression analysis with dependent functional data, including longitudinal functional data with scalar predictors. However, existing algorithms for Bayesian inference with these models only…

Methodology · Statistics 2023-06-14 Thomas Y. Sun , Daniel R. Kowal

Many scientific areas are faced with the challenge of extracting information from large, complex, and highly structured data sets. A great deal of modern statistical work focuses on developing tools for handling such data. This paper…

Methodology · Statistics 2017-10-05 Hyun Bin Kang , Matthew Reimherr , Mark Shriver , Peter Claes

The methodological contribution in this paper is motivated by biomechanical studies where data characterizing human movement are waveform curves representing joint measures such as flexion angles, velocity, acceleration, and so on. In many…

Methodology · Statistics 2024-02-08 Christian Acal , Ana M. Aguilera

Time Varying Functional Connectivity (TVFC) investigates how the interactions among brain regions vary over the course of an fMRI experiment. The transitions between different individual connectivity states can be modulated by changes in…

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