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Healthcare clinics regularly encounter dynamic data that changes due to variations in patient populations, treatment policies, medical devices, and emerging disease patterns. Deep learning models can suffer from catastrophic forgetting when…

Machine Learning · Computer Science 2023-11-09 Amritpal Singh , Mustafa Burak Gurbuz , Shiva Souhith Gantha , Prahlad Jasti

There is a clear need to involve patients in medical decisions. However, cognitive psychological research has highlighted the cognitive limitations of humans with respect to 1. Probabilistic assessment of the patient state and of potential…

Artificial Intelligence · Computer Science 2021-02-04 Yuval Shahar

Model-based approaches for image reconstruction, analysis and interpretation have made significant progress over the last decades. Many of these approaches are based on either mathematical, physical or biological models. A challenge for…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Daniel Rueckert , Julia A. Schnabel

Clinical trials assessing neurological treatment are challenging due to the diversity of brain function, and the difficulty in quantifying it. Traditional treatment studies in epilepsy use seizure frequency as the primary outcome measure,…

Applications · Statistics 2025-12-02 Ian Miller , Ann Hyslop , Colin Decker

When a new treatment is considered for use, whether a pharmaceutical drug or a search engine ranking algorithm, a typical question that arises is, will its performance exceed that of the current treatment? The conventional way to answer…

Machine Learning · Computer Science 2016-10-27 Nir Rosenfeld , Yishay Mansour , Elad Yom-Tov

Machine learning (ML) applications in medical artificial intelligence (AI) systems have shifted from traditional and statistical methods to increasing application of deep learning models. This survey navigates the current landscape of…

Machine Learning · Computer Science 2024-01-23 Elisa Warner , Joonsang Lee , William Hsu , Tanveer Syeda-Mahmood , Charles Kahn , Olivier Gevaert , Arvind Rao

Causal effect estimation from observational data requires careful adjustment for confounding. Classical estimators such as inverse probability weighting and augmented inverse probability weighting are effective under favorable model…

Machine Learning · Statistics 2026-04-28 Lei Wang , Debashis Ghosh

In high-stakes domains like medicine, it may be generally desirable for models to faithfully adhere to the context provided. But what happens if the context does not align with model priors or safety protocols? In this paper, we investigate…

Computation and Language · Computer Science 2026-04-21 Kaijie Mo , Siddhartha Venkatayogi , Chantal Shaib , Ramez Kouzy , Wei Xu , Byron C. Wallace , Junyi Jessy Li

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

In recent years, there is strong emphasis on mining medical data using machine learning techniques. A common problem is to obtain a noiseless set of textual documents, with a relevant content for the research question, and developing a…

Machine Learning · Computer Science 2023-10-03 Christian Internò , Eloisa Ambrosini

Prediction models are used amongst others to inform medical decisions on interventions. Typically, individuals with high risks of adverse outcomes are advised to undergo an intervention while those at low risk are advised to refrain from…

Clinical event sequences consist of thousands of clinical events that represent records of patient care in time. Developing accurate prediction models for such sequences is of a great importance for defining representations of a patient…

Machine Learning · Computer Science 2021-04-07 Jeong Min Lee , Milos Hauskrecht

Automatically reasoning with conflicting generic clinical guidelines is a burning issue in patient-centric medical reasoning where patient-specific conditions and goals need to be taken into account. It is even more challenging in the…

Artificial Intelligence · Computer Science 2019-02-21 Kristijonas Čyras , Tiago Oliveira

AI has the potential to augment human decision making. However, even high-performing models can produce inaccurate predictions when deployed. These inaccuracies, combined with automation bias, where humans overrely on AI predictions, can…

Human-Computer Interaction · Computer Science 2025-08-12 Sarah Jabbour , David Fouhey , Nikola Banovic , Stephanie D. Shepard , Ella Kazerooni , Michael W. Sjoding , Jenna Wiens

Clinical trials are an integral component of medical research. Trials require careful design to, for example, maintain the safety of participants, use resources efficiently and allow clinically meaningful conclusions to be drawn. Adaptive…

Methodology · Statistics 2025-07-17 James M. McGree , Antony M. Overstall , Mark Jones , Robert K. Mahar

Psychiatric intake is a sequential, high-stakes information-gathering process in which clinicians must decide what to ask, in what order, and how to interpret incomplete or ambiguous responses under limited time. Despite growing interest in…

Computation and Language · Computer Science 2026-04-29 Guan Gui , Peter Zandi , Jacob Taylor , Ananya Joshi

Adapting to latent confounded shift remains a core challenge in modern AI. This setting is driven by hidden variables that induce spurious correlations between inputs and outputs during training, leading models to rely on non-causal…

Machine Learning · Computer Science 2026-05-14 Jialin Yu , Yuxiang Zhou , Haoxuan Li , Junchi Yu , Mengyue Yang , Yulan He , Nevin L. Zhang , Philip Torr , Ricardo Silva

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Big data and business analytics are critical drivers of business and societal transformations. Uplift models support a firm's decision-making by predicting the change of a customer's behavior due to a treatment. Prior work examines models…

Machine Learning · Computer Science 2021-01-12 Robin M. Gubela , Stefan Lessmann

Machine Learning (ML) research has increased substantially in recent years, due to the success of predictive modeling across diverse application domains. However, well-known barriers exist when attempting to deploy ML models in high-stakes,…

Machine Learning · Computer Science 2024-09-19 Nathan Wolfrath , Joel Wolfrath , Hengrui Hu , Anjishnu Banerjee , Anai N. Kothari