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We propose an iterative programmatic planning (IPP) framework for solving grid-based tasks by synthesizing interpretable agent policies expressed in code using large language models (LLMs). Instead of relying on traditional search or…

Artificial Intelligence · Computer Science 2025-05-19 Ashwath Vaithinathan Aravindan , Zhisheng Tang , Mayank Kejriwal

Peptide-based drugs can bind to protein interaction sites that small molecules often cannot, and are easier to produce than large protein drugs. However, designing effective peptide binders is difficult. A typical peptide has an enormous…

Biomolecules · Quantitative Biology 2025-11-19 Xiaoqiong Xia , Cesar de la Fuente-Nunez

Across scientific domains, generating new models or optimizing existing ones while meeting specific criteria is crucial. Traditional machine learning frameworks for guided design use a generative model and a surrogate model (discriminator),…

Machine Learning · Computer Science 2024-05-29 Nataša Tagasovska , Vladimir Gligorijević , Kyunghyun Cho , Andreas Loukas

Creative image generation has emerged as a compelling area of research, driven by the need to produce novel and high-quality images that expand the boundaries of imagination. In this work, we propose a novel framework for creative…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Kunpeng Song , Ahmed Elgammal

In the design of deep neural architectures, recent studies have demonstrated the benefits of grouping subnetworks into a larger network. For examples, the Inception architecture integrates multi-scale subnetworks and the residual network…

Computer Vision and Pattern Recognition · Computer Science 2017-10-02 Jia-Ren Chang , Yong-Sheng Chen

Generating high-fidelity 3D geometries that satisfy specific parameter constraints has broad applications in design and engineering. However, current methods typically rely on large training datasets and struggle with controllability and…

Machine Learning · Computer Science 2026-01-21 Ghadi Nehme , Yanxia Zhang , Dule Shu , Matt Klenk , Faez Ahmed

Target-specific peptides, such as conotoxins, exhibit exceptional binding affinity and selectivity toward ion channels and receptors. However, their therapeutic potential remains underutilized due to the limited diversity of natural…

Biomolecules · Quantitative Biology 2025-05-07 Cheng Ge , Han-Shen Tae , Zhenqiang Zhang , Lu Lu , Zhijie Huang , Yilin Wang , Tao Jiang , Wenqing Cai , Shan Chang , David J. Adams , Rilei Yu

Large Language Models (LLMs) have demonstrated significant promise in automating software development tasks, yet their capabilities with respect to software design tasks remains largely unclear. This study investigates the capabilities of…

Software Engineering · Computer Science 2025-03-11 L. P. Franciscatto Guerra , N. Ernst

Content creators often draw inspiration from multiple visual sources, combining distinct elements to craft new compositions. Modern computational approaches now aim to emulate this fundamental creative process. Although recent diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Sara Dorfman , Dana Cohen-Bar , Rinon Gal , Daniel Cohen-Or

Power is the primary design objective of large-scale integrated circuits (ICs), especially for complex modern processors (i.e., CPUs). Accurate CPU power evaluation requires designers to go through the whole time-consuming IC implementation…

Hardware Architecture · Computer Science 2025-12-09 Qijun Zhang , Yao Lu , Mengming Li , Shang Liu , Zhiyao Xie

In recent years, with the rise of artificial intelligence and big data, there is an even greater demand for scaling out computing and memory capacity. Silicon interconnect fabric (Si-IF), a wafer-scale integration platform, promotes a…

Hardware Architecture · Computer Science 2022-08-30 Yousef Safari , Anja Kroon , Boris Vaisband

In-memory computing is an emerging computing paradigm that could enable deeplearning inference at significantly higher energy efficiency and reduced latency. The essential idea is to map the synaptic weights corresponding to each layer to…

Machine Learning · Computer Science 2019-06-11 Martino Dazzi , Abu Sebastian , Pier Andrea Francese , Thomas Parnell , Luca Benini , Evangelos Eleftheriou

Serving Large Language Models (LLMs) in production faces significant challenges from highly variable request patterns and severe resource fragmentation in serverless clusters. Current systems rely on static pipeline configurations that…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-12 Yanying Lin , Shijie Peng , Chengzhi Lu , Chengzhong Xu , Kejiang Ye

CLIP is one of the most popular foundational models and is heavily used for many vision-language tasks. However, little is known about the inner workings of CLIP. To bridge this gap we propose a study to quantify the interpretability in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Avinash Madasu , Yossi Gandelsman , Vasudev Lal , Phillip Howard

Diffusion models (DMs) have revolutionized image generation, producing high-quality images with applications spanning various fields. However, their ability to create hyper-realistic images poses significant challenges in distinguishing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Santosh , Li Lin , Irene Amerini , Xin Wang , Shu Hu

Designing secure architectures for system-on-chip (SoC) platforms is a highly intricate and time-intensive task, often requiring months of development and meticulous verification. Even minor architectural oversights can lead to critical…

Hardware Architecture · Computer Science 2025-07-16 Kshitij Raj , Atri Chatterjee , Patanjali SLPSK , Swarup Bhunia , Sandip Ray

We present Cyclotron, a framework and compiler for using recurrence equations to express streaming dataflow algorithms, which then get portably compiled to distributed topologies of interlinked processors. Our framework provides an input…

Programming Languages · Computer Science 2025-11-14 Shiv Sundram , Akhilesh Balasingam , Nathan Zhang , Kunle Olukotun , Fredrik Kjolstad

Topology diagrams are widely seen in power system applications, but their automatic generation is often easier said than done. When facing power transmission systems with strongly-meshed structures, existing approaches can hardly produce…

Systems and Control · Electrical Eng. & Systems 2023-03-21 Jingyu Wang , Jinfu Chen , Dongyuan Shi , Xianzhong Duan

Computer System Architecture serves as a crucial bridge between software applications and the underlying hardware, encompassing components like compilers, CPUs, coprocessors, and RTL designs. Its development, from early mainframes to modern…

Integrated sensing, computation, and communication (ISCC) has been recently considered as a promising technique for beyond 5G systems. In ISCC systems, the competition for communication and computation resources between sensing tasks for…

Information Theory · Computer Science 2023-06-07 Yinghui He , Guanding Yu , Yunlong Cai , Haiyan Luo
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