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Sparse Autoencoder (SAE) has emerged as a powerful tool for mechanistic interpretability of large language models. Recent works apply SAE to protein language models (PLMs), aiming to extract and analyze biologically meaningful features from…

Quantitative Methods · Quantitative Biology 2026-01-21 Xiangyu Liu , Haodi Lei , Yi Liu , Yang Liu , Wei Hu

Protein language models (PLMs) have demonstrated remarkable success in protein modeling and design, yet their internal mechanisms for predicting structure and function remain poorly understood. Here we present a systematic approach to…

Biomolecules · Quantitative Biology 2024-12-18 Elana Simon , James Zou

Machine unlearning is a promising approach to improve LLM safety by removing unwanted knowledge from the model. However, prevailing gradient-based unlearning methods suffer from issues such as high computational costs, hyperparameter…

Machine Learning · Computer Science 2025-04-14 Aashiq Muhamed , Jacopo Bonato , Mona Diab , Virginia Smith

LLMs increasingly require surgical model editing to enhance domain-specific capabilities without incurring the computational cost or catastrophic forgetting associated with full fine-tuning. Sparse Autoencoders (SAEs) have emerged as a…

Machine Learning · Computer Science 2026-05-28 Li Lei , Madalina Ciobanu , Qingqing Mao , Ritankar Das

Understanding training dynamics and feature evolution is crucial for the mechanistic interpretability of large language models (LLMs). Although sparse autoencoders (SAEs) have been used to identify features within LLMs, a clear picture of…

Machine Learning · Computer Science 2025-06-04 Yang Xu , Yi Wang , Hengguan Huang , Hao Wang

In recent years, significant progress has been made in the field of robotic reinforcement learning (RL), enabling methods that handle complex image observations, train in the real world, and incorporate auxiliary data, such as…

Sparse autoencoders (SAEs) are one of the main methods to interpret the inner workings of deep neural networks (DNNs), decomposing activations into higher-dimensional features. However, they exhibit critical shortcomings where a large…

Machine Learning · Computer Science 2026-05-19 Michał Brzozowski , Neo Christopher Chung

Understanding and mitigating the potential risks associated with foundation models (FMs) hinges on developing effective interpretability methods. Sparse Autoencoders (SAEs) have emerged as a promising tool for disentangling FM…

Machine Learning · Computer Science 2024-11-04 Aashiq Muhamed , Mona Diab , Virginia Smith

Large language models (LLMs) are powerful but static; they lack mechanisms to adapt their weights in response to new tasks, knowledge, or examples. We introduce Self-Adapting LLMs (SEAL), a framework that enables LLMs to self-adapt by…

Machine Learning · Computer Science 2025-09-19 Adam Zweiger , Jyothish Pari , Han Guo , Ekin Akyürek , Yoon Kim , Pulkit Agrawal

Sparse autoencoders (SAEs) have emerged as a promising approach in language model interpretability, offering unsupervised extraction of sparse features. For interpretability methods to succeed, they must identify abstract features across…

Machine Learning · Computer Science 2025-09-08 Lovis Heindrich , Philip Torr , Fazl Barez , Veronika Thost

Sparse auto-encoders (SAEs) have become a prevalent tool for interpreting language models' inner workings. However, it is unknown how tightly SAE features correspond to computationally important directions in the model. This work…

Machine Learning · Computer Science 2025-02-25 Thomas Dooms , Daniel Wilhelm

We investigate whether sparse autoencoders (SAEs) can be used to remove knowledge from language models. We use the biology subset of the Weapons of Mass Destruction Proxy dataset and test on the gemma-2b-it and gemma-2-2b-it language…

Machine Learning · Computer Science 2024-11-05 Eoin Farrell , Yeu-Tong Lau , Arthur Conmy

Sparse autoencoders (SAEs) are a promising approach to interpreting the internal representations of transformer language models. However, SAEs are usually trained separately on each transformer layer, making it difficult to use them to…

Machine Learning · Computer Science 2025-02-25 Tim Lawson , Lucy Farnik , Conor Houghton , Laurence Aitchison

Learned Sparse IR models, such as SPLADE, offer an excellent efficiency-effectiveness tradeoff. However, they rely on the underlying backbone vocabulary, which might hinder performance (polysemicity and synonymy) and pose a challenge for…

Information Retrieval · Computer Science 2026-04-24 Yuxuan Zong , Mathias Vast , Basile Van Cooten , Laure Soulier , Benjamin Piwowarski

Sparse autoencoders (SAEs) are a popular tool for interpreting large language model activations, but their utility in addressing open questions in interpretability remains unclear. In this work, we demonstrate their effectiveness by using…

Machine Learning · Computer Science 2025-04-21 Dmitrii Kharlapenko , Stepan Shabalin , Fazl Barez , Arthur Conmy , Neel Nanda

Large language models (LLMs) have achieved remarkable progress, yet their internal mechanisms remain largely opaque, posing a significant challenge to their safe and reliable deployment. Sparse autoencoders (SAEs) have emerged as a…

Computation and Language · Computer Science 2026-02-11 Jiaojiao Han , Wujiang Xu , Mingyu Jin , Mengnan Du

Audio pretrained models are widely employed to solve various tasks in speech processing, sound event detection, or music information retrieval. However, the representations learned by these models are unclear, and their analysis mainly…

To truly understand vision models, we must not only interpret their learned features but also validate these interpretations through controlled experiments. While earlier work offers either rich semantics or direct control, few post-hoc…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Samuel Stevens , Wei-Lun Chao , Tanya Berger-Wolf , Yu Su

Reinforcement learning (RL) has become the dominant paradigm for improving the performance of language models on complex reasoning tasks. Despite the substantial empirical gains demonstrated by RL-based training methods like GRPO, a…

Artificial Intelligence · Computer Science 2025-10-27 Jiayu Wang , Yifei Ming , Zixuan Ke , Caiming Xiong , Shafiq Joty , Aws Albarghouthi , Frederic Sala

Radiological services are experiencing unprecedented demand, leading to increased interest in automating radiology report generation. Existing Vision-Language Models (VLMs) suffer from hallucinations, lack interpretability, and require…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Ahmed Abdulaal , Hugo Fry , Nina Montaña-Brown , Ayodeji Ijishakin , Jack Gao , Stephanie Hyland , Daniel C. Alexander , Daniel C. Castro
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