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This report describes ARIS (Auto-Research-in-sleep), an open-source research harness for autonomous research, including its architecture, assurance mechanisms, and early deployment experience. The performance of agent systems built on LLMs…

Software Engineering · Computer Science 2026-05-06 Ruofeng Yang , Yongcan Li , Shuai Li

Neuroscience data are highly fragmented across labs, formats, and experimental paradigms, and reuse often requires substantial manual effort. A persistent roadblock to data reuse and integration is the need to decipher bespoke and diverse…

Machine Learning · Computer Science 2026-05-15 Ling-Qi Zhang , Kristin Branson

Keeping pace with the rapid growth of academia literature presents a significant challenge for researchers, funding bodies, and academic societies. To address the time-consuming manual effort required for scholarly discovery, we present a…

Machine Learning · Computer Science 2025-09-15 Om Vishesh , Harshad Khadilkar , Deepak Akkil

Artificial intelligence (AI) agents are emerging as transformative tools in drug discovery, with the ability to autonomously reason, act, and learn through complicated research workflows. Building on large language models (LLMs) coupled…

This paper studies standard controller architectures for agentic AI and derives automata-theoretic models of their interaction behavior via trace semantics and abstraction. We model an agent implementation as a finite control program…

Artificial Intelligence · Computer Science 2026-02-02 Roham Koohestani , Ziyou Li , Anton Podkopaev , Maliheh Izadi

The pursuit of human-level artificial intelligence (AI) has significantly advanced the development of autonomous agents and Large Language Models (LLMs). LLMs are now widely utilized as decision-making agents for their ability to interpret…

Large language model (LLM) agents face fundamental limitations in long-horizon reasoning due to finite context windows, making effective memory management critical. Existing methods typically handle long-term memory (LTM) and short-term…

Computation and Language · Computer Science 2026-05-01 Yi Yu , Liuyi Yao , Yuexiang Xie , Qingquan Tan , Jiaqi Feng , Yaliang Li , Libing Wu

Recent advances in large language models have sparked growing interest in AI agents capable of solving complex, real-world tasks. However, most existing agent systems rely on manually crafted configurations that remain static after…

Artificial Intelligence · Computer Science 2025-09-03 Jinyuan Fang , Yanwen Peng , Xi Zhang , Yingxu Wang , Xinhao Yi , Guibin Zhang , Yi Xu , Bin Wu , Siwei Liu , Zihao Li , Zhaochun Ren , Nikos Aletras , Xi Wang , Han Zhou , Zaiqiao Meng

As Large Language Models (LLMs) have become integral to both research and daily operations, rigorous evaluation is crucial. This assessment is important not only for individual tasks but also for understanding their societal impact and…

Software Engineering · Computer Science 2024-04-02 Zeeshan Rasheed , Muhammad Waseem , Kari Systä , Pekka Abrahamsson

Multi-agent systems built on Large Language Models (LLMs) show exceptional promise for complex collaborative problem-solving, yet they face fundamental challenges stemming from context window limitations that impair memory consistency, role…

Artificial Intelligence · Computer Science 2026-01-13 Sizhe Yuen , Francisco Gomez Medina , Ting Su , Yali Du , Adam J. Sobey

Transformer-based large language models are rapidly advancing in the field of machine learning research, with applications spanning natural language, biology, chemistry, and computer programming. Extreme scaling and reinforcement learning…

Chemical Physics · Physics 2023-04-12 Daniil A. Boiko , Robert MacKnight , Gabe Gomes

Lifelong learning is essential for intelligent agents operating in dynamic environments. Current large language model (LLM)-based agents, however, remain stateless and unable to accumulate or transfer knowledge over time. Existing…

Artificial Intelligence · Computer Science 2025-06-02 Junhao Zheng , Xidi Cai , Qiuke Li , Duzhen Zhang , ZhongZhi Li , Yingying Zhang , Le Song , Qianli Ma

AI agents are increasingly embedded in real software systems, where they execute multi-step workflows through multi-turn dialogue, tool invocations, and intermediate decisions. These long execution histories, called agentic traces, make…

Software Engineering · Computer Science 2026-05-12 Reshabh K Sharma , Shraddha Barke , Benjamin Zorn

Advances in large language models (LLMs) are rapidly transforming scientific work, yet empirical evidence on how these systems reshape research activities remains limited. We report a mixed-methods pilot evaluation of an AI-orchestrated…

Computers and Society · Computer Science 2026-02-24 Yuan An

Artificial intelligence (AI) is increasingly being explored as a tool to support pharmacometric modeling, particularly in addressing the coding challenges associated with NONMEM. In this study, we evaluated the ability of seven AI agents to…

Other Quantitative Biology · Quantitative Biology 2025-07-14 Wenhao Zheng , Wanbing Wang , Carl M. J. Kirkpatrick , Cornelia B. Landersdorfer , Huaxiu Yao , Jiawei Zhou

With the rapid advancement of Large Language Models (LLMs) and Artificial Intelligence (AI) agents, agentic workflows are showing transformative potential in education. This study introduces the Agentic Workflow for Education (AWE), a…

Computers and Society · Computer Science 2025-09-03 Yuan-Hao Jiang , Yijie Lu , Ling Dai , Jiatong Wang , Ruijia Li , Bo Jiang

The delivery of traditional substance education has remained problematic due to challenges in scalability, personalization, and the currency of information in a rapidly evolving substance use landscape. While artificial intelligence (AI)…

Computation and Language · Computer Science 2026-05-04 Kosar Haghani , Zahra Kolagar , Mohammed Atiquzzaman

Autonomous language-model agents are increasingly evaluated on long-horizon tool-use tasks, but existing benchmarks rarely capture the complexity and nuance of real scientific work. To address this gap, we introduce Collider-Bench, a…

Machine Learning · Computer Science 2026-05-15 Darius A. Faroughy , Sofia Palacios Schweitzer , Ian Pang , Siddharth Mishra-Sharma , David Shih

Large Language Models (LLMs) and other foundation models are increasingly used as the core of AI agents. In agentic workflows, these agents plan tasks, interact with humans and peers, and influence scientific outcomes across federated and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-21 Renan Souza , Amal Gueroudji , Stephen DeWitt , Daniel Rosendo , Tirthankar Ghosal , Robert Ross , Prasanna Balaprakash , Rafael Ferreira da Silva