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Evolutionary dynamics and patterns of molecular evolution are strongly influenced by selection on linked regions of the genome, but our quantitative understanding of these effects remains incomplete. Recent work has focused on predicting…

Populations and Evolution · Quantitative Biology 2013-05-29 Benjamin H. Good , Michael M. Desai

Models of population growth and extinction are an increasingly popular subject of study. However, consequences of stochasticity and noise in shaping distributions and outcomes are not sufficiently explored. Here we consider a distributed…

Statistical Mechanics · Physics 2020-11-11 Bertrand Ottino-Löffler , Mehran Kardar

The formula for the probability of fixation of a new mutation is widely used in theoretical population genetics and molecular evolution. Here we derive a series of identities, inequalities and approximations for the exact probability of…

Populations and Evolution · Quantitative Biology 2015-03-10 David M. McCandlish , Charles L. Epstein , Joshua B. Plotkin

We present an explicit unified stochastic model of fluctuations in population size due to random birth, death, density-dependent competition and environmental fluctuations. Stochastic dynamics provide insight into small populations,…

Populations and Evolution · Quantitative Biology 2008-07-31 Alexei J. Drummond , Peter D. Drummond

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

Populations and Evolution · Quantitative Biology 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

Phenotypes of individuals in a population of organisms are not fixed. Phenotypic fluctuations, which describe temporal variation of the phenotype of an individual or individual-to-individual variation across a population, are present in…

Populations and Evolution · Quantitative Biology 2018-08-15 Hong-Yan Shih , Harry Mickalide , David T. Fraebel , Nigel Goldenfeld , Seppe Kuehn

Evolutionary game theory is a framework to formalize the evolution of collectives ("populations") of competing agents that are playing a game and, after every round, update their strategies to maximize individual payoffs. There are two…

Adaptation and Self-Organizing Systems · Physics 2021-01-05 Sergey Denisov , Olga Vershinina , Juzar Thingna , Peter Hänggi , Mikhail Ivanchenko

The coalescent is a stochastic process representing ancestral lineages in a population undergoing neutral genetic drift. Originally defined for a well-mixed population, the coalescent has been adapted in various ways to accommodate spatial,…

Populations and Evolution · Quantitative Biology 2024-07-02 Benjamin Allen , Alex McAvoy

We present new theoretical and empirical results on the probability distributions of species persistence times in natural ecosystems. Persistence times, defined as the timespans occurring between species' colonization and local extinction…

Populations and Evolution · Quantitative Biology 2012-03-21 S. Suweis , E. Bertuzzo , L. Mari , I. Rodriguez-Iturbe , A. Maritan , A. Rinaldo

The origin of diversification and coexistence of genes and species have been traditionally studied in isolated biological levels. Ecological and evolutionary views have focused on the mechanisms that enable or constrain species coexistence,…

Populations and Evolution · Quantitative Biology 2008-07-18 Carlos J. Melian , David Alonso , Diego P. Vazquez , James Regetz

Theoretically, communities at or near their equilibrium species number resist entry of new species. Such 'biotic resistance' recently has been questioned because of successful entry of alien species into diverse natural communities. Data on…

Populations and Evolution · Quantitative Biology 2010-04-15 Colleen K. Kellya , Stephen J. Blundell , Michael G. Bowler , Gordon A. Fox , Paul H. Harvey , Mark R. Lomas , F. Ian Woodward

The dynamical mechanisms that can stabilize the coexistence of species (or strategies) are of substantial interest for the maintenance of biodiversity and in sociobehavioural dynamics. We investigate the mean extinction time in the…

Populations and Evolution · Quantitative Biology 2010-03-16 Markus Schütt , Jens Christian Claussen

In many biological processes, the size of a population changes stochastically with time, and recent work in the context of cancer and bacterial growth have focused on the situation when the mean population size grows exponentially. Here,…

Populations and Evolution · Quantitative Biology 2025-08-27 Kavita Jain , Hitesh Sumuni

We consider the Moran process in a graph called the "star" and obtain the asymptotic expression for the fixation probability of a single mutant when the size of the graph is large. The expression obtained corrects the previously known…

Populations and Evolution · Quantitative Biology 2016-03-21 Fabio A. C. C. Chalub

We present analytical expressions for the time-dependent and stationary probability distributions corresponding to a stochastically perturbed one-dimensional flow with critical points, in two physically relevant situations: delayed…

Statistical Mechanics · Physics 2007-05-23 V. Balakrishnan , C. Van den Broeck , I. Bena

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

Populations and Evolution · Quantitative Biology 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

We analyze the population dynamics of a broad class of fitness functions that exhibit epochal evolution---a dynamical behavior, commonly observed in both natural and artificial evolutionary processes, in which long periods of stasis in an…

adap-org · Physics 2007-05-23 James P. Crutchfield , Erik van Nimwegen

In population genetics, diffusions on the unit interval are often used to model the frequency path of an allele. In this setting we derive approximations for fixation probabilities, expected hitting times and the expected…

Probability · Mathematics 2018-09-18 Peter Pfaffelhuber , Anton Wakolbinger

We examine the switching dynamics of a stochastic population subjected to a deterministically time-varying environment. Our approach is demonstrated in the realm of ecology on a problem of population establishment. Here, by assuming a…

Statistical Mechanics · Physics 2020-02-19 Tom Israeli , Michael Assaf

We model evolution according to an asymmetric game as occurring in multiple finite populations, one for each role in the game, and study the effect of subjecting individuals to stochastic strategy mutations. We show that, when these…

Populations and Evolution · Quantitative Biology 2015-12-22 Carl Veller , Laura K. Hayward