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Auto-regressive LLM-based software engineering (SWE) agents, henceforth SWE agents, have made tremendous progress (>60% on SWE-Bench Verified) on real-world coding challenges including GitHub issue resolution. SWE agents use a combination…

Software Engineering · Computer Science 2025-04-15 Timothy Bula , Saurabh Pujar , Luca Buratti , Mihaela Bornea , Avirup Sil

Multimodal Large Language Models are increasingly applied to biomedical imaging, yet scientific reasoning for microscopy remains limited by the scarcity of large-scale, high-quality training data. We introduce MicroVQA++, a three-stage,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Manyu Li , Ruian He , Chenxi Ma , Weimin Tan , Bo Yan

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

Existing LLM agents for computational materials science are constrained by pipeline-bounded architectures tied to specific simulation codes and by dependence on manually written tool functions that grow with task scope. We present MatClaw,…

Materials Science · Physics 2026-05-25 Chenmu Zhang , Boris I. Yakobson

The emerging area of computational pathology (CPath) is ripe ground for the application of deep learning (DL) methods to healthcare due to the sheer volume of raw pixel data in whole-slide images (WSIs) of cancerous tissue slides. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-04-23 Jevgenij Gamper , Navid Alemi Koohbanani , Ksenija Benes , Simon Graham , Mostafa Jahanifar , Syed Ali Khurram , Ayesha Azam , Katherine Hewitt , Nasir Rajpoot

Despite the growing adoption of electronic health records, many processes still rely on paper documents, reflecting the heterogeneous real-world conditions in which healthcare is delivered. The manual transcription process is time-consuming…

Liver diseases pose a significant global health burden, impacting many individuals and having substantial economic and social consequences. Rising liver problems are considered a fatal disease in many countries, such as Egypt and Moldova.…

Artificial Intelligence · Computer Science 2025-03-21 Ritesh Chandra , Sadhana Tiwari , Satyam Rastogi , Sonali Agarwal

Evaluating AI agents that solve real-world tasks through function-call sequences remains an open challenge. Existing agentic benchmarks often reduce evaluation to a binary judgment of the final state, overlooking critical aspects such as…

Artificial Intelligence · Computer Science 2025-09-26 Panagiotis Michelakis , Yiannis Hadjiyiannis , Dimitrios Stamoulis

Progress in biomedical Named Entity Recognition (NER) and Entity Linking (EL) is currently hindered by a fragmented data landscape, a lack of resources for building explainable models, and the limitations of semantically-blind evaluation…

Computation and Language · Computer Science 2025-11-17 Nishant Mishra , Wilker Aziz , Iacer Calixto

Background: Cancers are highly heterogeneous with different subtypes. These subtypes often possess different genetic variants, present different pathological phenotypes, and most importantly, show various clinical outcomes such as varied…

Graphics · Computer Science 2014-07-09 Hao Ding , Chao Wang , Kun Huang , Raghu Machiraju

In this study, we built an end-to-end tumor-infiltrating lymphocytes (TILs) assessment pipeline within QuPath, demonstrating the potential of easily accessible tools to perform complex tasks in a fully automatic fashion. First, we trained a…

The pathogenesis of cancer in human is still poorly understood. With the rapid development of high-throughput sequencing technologies, huge volumes of cancer genomics data have been generated. Deciphering those data poses great…

Genomics · Quantitative Biology 2016-04-06 Junhua Zhang , Shihua Zhang

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Motivation: Multi-omics integration can improve cancer subtyping, but modality informativeness and noise vary across cancer types and patients. Existing graph-based methods optimize modality weights jointly with the classification objective…

Machine Learning · Computer Science 2026-04-28 Boyang Fan , Hengchuang Yin , Siyu Yi , Yifan Wang , Zhicheng Li , Leijiyu Zhou , Jiancheng Lv , Wei Ju

We introduce WordScape, a novel pipeline for the creation of cross-disciplinary, multilingual corpora comprising millions of pages with annotations for document layout detection. Relating visual and textual items on document pages has…

Knowledge Graph Question Answering (KGQA) aims to answer user questions by reasoning over Knowledge Graphs (KGs). Recent KGQA methods mainly follow the retrieval-augmented generation paradigm to ground Large Language Models~(LLMs) with…

Artificial Intelligence · Computer Science 2026-05-12 Shengxiang Gao , Chao Lei , Jey Han Lau , Jianzhong Qi

With their high information density and intuitive readability, charts have become the de facto medium for data analysis and communication across disciplines. Recent multimodal large language models (MLLMs) have made notable progress in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Boran Wang , Xinming Wang , Yi Chen , Xiang Li , Jian Xu , Jing Yuan , Chenglin Liu

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Shahad Albastaki , Anabia Sohail , Iyyakutti Iyappan Ganapathi , Basit Alawode , Asim Khan , Sajid Javed , Naoufel Werghi , Mohammed Bennamoun , Arif Mahmood

Accurate diagnosis of ocular surface diseases is critical in optometry and ophthalmology, which hinge on integrating clinical data sources (e.g., meibography imaging and clinical metadata). Traditional human assessments lack precision in…

Computation and Language · Computer Science 2024-10-02 Chun-Hsiao Yeh , Jiayun Wang , Andrew D. Graham , Andrea J. Liu , Bo Tan , Yubei Chen , Yi Ma , Meng C. Lin

Machine learning and Large language models (LLMs) for vulnerability detection has received significant attention in recent years. Unfortunately, state-of-the-art techniques show that LLMs are unsuccessful in even distinguishing the…

Cryptography and Security · Computer Science 2025-08-05 Mohammed Sayagh , Mohammad Ghafari