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Mammography screening for early detection of breast lesions currently suffers from high amounts of false positive findings, which result in unnecessary invasive biopsies. Diffusion-weighted MR images (DWI) can help to reduce many of these…

Motivated by differential co-expression analysis in genomics, we consider in this paper estimation and testing of high-dimensional differential correlation matrices. An adaptive thresholding procedure is introduced and theoretical…

Methodology · Statistics 2015-10-22 T. Tony Cai , Anru Zhang

Improving breast cancer detection and monitoring techniques is a critical objective in healthcare, driving the need for innovative imaging technologies and diagnostic approaches. This study introduces a novel multi-tiered self-contrastive…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Christoforos Galazis , Huiyi Wu , Igor Goryanin

Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Churan Wang , Fei Gao , Lijun Yan , Siwen Wang , Yizhou Yu , Yizhou Wang

One of the key impediments for developing and assessing robust medical imaging algorithms is limited access to large-scale datasets with suitable annotations. Synthetic data generated with plausible physical and biological constraints may…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Christopher Wiedeman , Anastasiia Sarmakeeva , Elena Sizikova , Daniil Filienko , Miguel Lago , Jana G. Delfino , Aldo Badano

Locating region of interest for breast cancer masses in the mammographic image is a challenging problem in medical image processing. In this research work, the keen idea is to efficiently extract suspected mass region for further…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 BV Divyashree , Amarnath R , Naveen M , G Hemantha Kumar

Advancements in generative modeling are pushing the state-of-the-art in synthetic medical image generation. These synthetic images can serve as an effective data augmentation method to aid the development of more accurate machine learning…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Mohammed Talha Alam , Raza Imam , Mohammad Areeb Qazi , Asim Ukaye , Karthik Nandakumar

Breast cancer is the most common malignant tumor among women and the second cause of cancer-related death. Early diagnosis in clinical practice is crucial for timely treatment and prognosis. Dynamic contrast-enhanced magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zixian Li , Yuming Zhong , Yi Wang

Breast density is an important risk factor for breast cancer that also affects the specificity and sensitivity of screening mammography. Current federal legislation mandates reporting of breast density for all women undergoing breast…

This paper focuses on the classification task of breast ultrasound images and researches on the reliability measurement of classification results. We proposed a dual-channel evaluation framework based on the proposed inference reliability…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Shuge Lei , Haonan Hu , Dasheng Sun , Huabin Zhang , Kehong Yuan , Jian Dai , Jijun Tang , Yan Tong

In coherent X-ray diffraction microscopy the diffraction pattern generated by a sample illuminated with coherent x-rays is recorded, and a computer algorithm recovers the unmeasured phases to synthesize an image. By avoiding the use of a…

Breast density assessment is a crucial component of mammographic interpretation, with high breast density (BI-RADS categories C and D) representing both a significant risk factor for developing breast cancer and a technical challenge for…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Peyman Sharifian , Xiaotong Hong , Alireza Karimian , Mehdi Amini , Hossein Arabi

Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Aleksandar Vakanski , Min Xian , Phoebe Freer

Supervised deep learning relies on the assumption that enough training data is available, which presents a problem for its application to several fields, like medical imaging. On the example of a binary image classification task (breast…

Computer Vision and Pattern Recognition · Computer Science 2019-02-22 Lukas Jendele , Ondrej Skopek , Anton S. Becker , Ender Konukoglu

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Lijun Yan , Churan Wang , Fangwei Zhong , Yizhou Wang

Histological examination is crucial for cancer diagnosis, including hematoxylin and eosin (H&E) staining for mapping morphology and immunohistochemistry (IHC) staining for revealing chemical information. Recently developed two-color…

Tissues and Organs · Quantitative Biology 2023-09-22 Hongli Ni , Chinmayee Prabhu Dessai , Haonan Lin , Wei Wang , Shaoxiong Chen , Yuhao Yuan , Xiaowei Ge , Jianpeng Ao , Nolan Vild , Ji-Xin Cheng

Accurate segmentation of laryngo-pharyngeal tumors is crucial for precise diagnosis and effective treatment planning. However, traditional single-modality imaging methods often fall short of capturing the complex anatomical and pathological…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Junhao Wu , Yun Li , Junhao Li , Jingliang Bian , Xiaomao Fan , Wenbin Lei , Ruxin Wang

Breast density estimation is one of the key tasks in recognizing individuals predisposed to breast cancer. It is often challenging because of low contrast and fluctuations in mammograms' fatty tissue background. Most of the time, the breast…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Vikash Gupta , Mutlu Demirer , Robert W. Maxwell , Richard D. White , Barbaros Selnur Erdal

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest