English
Related papers

Related papers: ViroBench: Benchmarking Nucleotide Foundation Mode…

200 papers

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

Digital pathology has seen the advent of a wealth of foundational models (FM), yet to date their performance on cell phenotyping has not been benchmarked in a unified manner. We therefore propose PhenoBench: A comprehensive benchmark for…

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related mortality in women globally. Mammography is essential for the early detection and diagnosis of breast lesions. Despite recent progress in foundation…

With the growth of high-quality data and advancement in visual pre-training paradigms, Video Foundation Models (VFMs) have made significant progress recently, demonstrating their remarkable performance on traditional video understanding…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Xinhao Li , Zhenpeng Huang , Jing Wang , Kunchang Li , Limin Wang

Structural biology relies on accurate three-dimensional biomolecular structures to advance our understanding of biological functions, disease mechanisms, and therapeutics. While recent advances in deep learning have enabled the development…

Biomolecules · Quantitative Biology 2025-04-02 Yizhen Luo , Jiashuo Wang , Siqi Fan , Zaiqing Nie

We introduce a comprehensive framework for modeling single cell transcriptomic responses to perturbations, aimed at standardizing benchmarking in this rapidly evolving field. Our approach includes a modular and user-friendly model…

Virtual cell (VC) models aim to predict cellular responses to any perturbations in silico and have emerged as a promising approach for drug discovery and precision medicine. Yet, a clear gap still remains: while models routinely reported…

Cell Behavior · Quantitative Biology 2026-05-01 Xinjie Mao , Songming Zhang , Qianhong Wen , Xiangyu Wen , Kedu Jin , Hao Wu , Shuizhou Chen , Yuqiang Li , Lei Bai , Qi Liu , Ning Ding , Siqi Sun , Zhangyang Gao

Modern computational neuroscience strives to develop complex network models to explain dynamics and function of brains in health and disease. This process goes hand in hand with advancements in the theory of neuronal networks and increasing…

Despite the remarkable progress of Vision-Language Models (VLMs) in adopting "Thinking-with-Images" capabilities, accurately evaluating the authenticity of their reasoning process remains a critical challenge. Existing benchmarks mainly…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Xuchen Li , Xuzhao Li , Renjie Pi , Shiyu Hu , Jian Zhao , Jiahui Gao

Cell-type-specific marker genes are fundamental to plant biology, yet existing resources primarily rely on curated databases or high-throughput studies without explicitly modeling the supporting evidence found in scientific literature. We…

Computation and Language · Computer Science 2026-05-13 Sajib Acharjee Dip , Song Li , Liqing Zhang

Foundation models, first introduced in 2021, refer to large-scale pretrained models (e.g., large language models (LLMs) and vision-language models (VLMs)) that learn from extensive unlabeled datasets through unsupervised methods, enabling…

Foundation models have enabled rapid progress across many specialized domains by leveraging large-scale pre-training on unlabeled data, demonstrating strong generalization to a variety of downstream tasks. While such models have gained…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Mirali Purohit , Bimal Gajera , Vatsal Malaviya , Irish Mehta , Kunal Kasodekar , Jacob Adler , Steven Lu , Umaa Rebbapragada , Hannah Kerner

Biomedical Foundation Models (FMs) are rapidly transforming AI-enabled healthcare research and entering clinical validation. However, their susceptibility to learning non-biological technical features -- including variations in…

Biometric systems based on brain activity have been proposed as an alternative to passwords or to complement current authentication techniques. By leveraging the unique brainwave patterns of individuals, these systems offer the possibility…

Cryptography and Security · Computer Science 2024-07-12 Avinash Kumar Chaurasia , Matin Fallahi , Thorsten Strufe , Philipp Terhörst , Patricia Arias Cabarcos

Cytology is essential for cancer diagnostics and screening due to its minimally invasive nature. However, the development of robust deep learning models for digital cytology is challenging due to the heterogeneity in staining and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Vedrana Ivezić , Ashwath Radhachandran , Ekaterina Redekop , Shreeram Athreya , Dongwoo Lee , Vivek Sant , Corey Arnold , William Speier

Vision-language generative reward models (VL-GenRMs) play a crucial role in aligning and evaluating multimodal AI systems, yet their own evaluation remains under-explored. Current assessment methods primarily rely on AI-annotated preference…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Lei Li , Yuancheng Wei , Zhihui Xie , Xuqing Yang , Yifan Song , Peiyi Wang , Chenxin An , Tianyu Liu , Sujian Li , Bill Yuchen Lin , Lingpeng Kong , Qi Liu

Video foundation models aim to integrate video understanding, generation, editing, and instruction following within a single framework, making them a central direction for next-generation multimodal systems. However, existing evaluation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Jianhui Wei , Xiaotian Zhang , Yichen Li , Yuan Wang , Yan Zhang , Ziyi Chen , Zhihang Tang , Wei Xu , Zuozhu Liu

Geo-Foundation Models (GFMs) have been evaluated across diverse Earth observation task including multiple domains and have demonstrated strong potential of producing reliable maps even with sparse labels. However, benchmarking GFMs for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Saurabh Kaushik , Lalit Maurya , Beth Tellman

Using multimodal foundation models to analyze table images is a high-value yet challenging application in consumer and enterprise scenarios. Despite its importance, current evaluations rely largely on structured-text tables or clean…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Junzhe Huang , Xiaoxiao Sun , Yan Yang , Yuxuan Hou , Ruotian Zhang , Sirui Li , Hehe Fan , Serena Yeung-Levy , Xin Yu

The realization of autonomous scientific experimentation is currently limited by LLMs' struggle to grasp the strict procedural logic and accuracy required by biological protocols. To address this fundamental challenge, we present…

Computation and Language · Computer Science 2026-01-22 Yuyang Liu , Liuzhenghao Lv , Xiancheng Zhang , Jingya Wang Li Yuan , Yonghong Tian