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Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken

The advent of foundation models has heralded a new era in medical artificial intelligence (AI), enabling the extraction of generalizable representations from large-scale unlabeled datasets. However, current ophthalmic AI paradigms are…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tienyu Chang , Zhen Chen , Renjie Liang , Jinyu Ding , Jie Xu , Sunu Mathew , Amir Reza Hajrasouliha , Andrew J. Saykin , Ruogu Fang , Yu Huang , Jiang Bian , Qingyu Chen

The emergence of large-scale Mixture of Experts (MoE) models represents a significant advancement in artificial intelligence, offering enhanced model capacity and computational efficiency through conditional computation. However, deploying…

Machine Learning · Computer Science 2025-01-23 Jiacheng Liu , Peng Tang , Wenfeng Wang , Yuhang Ren , Xiaofeng Hou , Pheng-Ann Heng , Minyi Guo , Chao Li

Due to the high stakes in medical decision-making, there is a compelling demand for interpretable deep learning methods in medical image analysis. Concept Bottleneck Models (CBM) have emerged as an active interpretable framework…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yibo Gao , Zheyao Gao , Xin Gao , Yuanye Liu , Bomin Wang , Xiahai Zhuang

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking…

Artificial Intelligence · Computer Science 2026-05-26 Jinyue Li , Yuci Liang , Qiankun Li , Xinheng Lyu , Jiayu Qian , Huabao Chen , Kun Wang , Zhigang Zeng , Anil Anthony Bharath , Yang Liu

Mixture-of-Experts (MoE) architectures are evolving towards finer granularity to improve parameter efficiency. However, existing MoE designs face an inherent trade-off between the granularity of expert specialization and hardware execution…

Computation and Language · Computer Science 2026-02-06 Jingze Shi , Zhangyang Peng , Yizhang Zhu , Yifan Wu , Guang Liu , Yuyu Luo

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Zhe Xu , Ziyi Liu , Junlin Hou , Jiabo Ma , Cheng Jin , Yihui Wang , Zhixuan Chen , Zhengyu Zhang , Fuxiang Huang , Zhengrui Guo , Fengtao Zhou , Yingxue Xu , Xi Wang , Ronald Cheong Kin Chan , Li Liang , Hao Chen

Motivation: Despite advances in the computational analysis of high-throughput molecular profiling assays (e.g. transcriptomics), a dichotomy exists between methods that are simple and interpretable, and ones that are complex but with lower…

Machine Learning · Computer Science 2023-06-12 Pedro Henrique da Costa Avelar , Min Wu , Sophia Tsoka

Automated retinal image medical description generation is crucial for streamlining medical diagnosis and treatment planning. Existing challenges include the reliance on learned retinal image representations, difficulties in handling…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Nagur Shareef Shaik , Teja Krishna Cherukuri , Dong Hye Ye

Objective: Currently, a major limitation for natural language processing (NLP) analyses in clinical applications is that a concept can be referenced in various forms across different texts. This paper introduces Multi-Ontology Refined…

Computation and Language · Computer Science 2020-04-15 Steven Jiang , Weiyi Wu , Naofumi Tomita , Craig Ganoe , Saeed Hassanpour

We propose Chain-of-Experts (CoE), a new Mixture-of-Experts (MoE) architecture that introduces sequential expert communication within each layer. Unlike traditional MoE models, where experts operate independently in parallel, CoE processes…

Machine Learning · Computer Science 2025-06-25 Zihan Wang , Rui Pan , Jiarui Yao , Robert Csordas , Linjie Li , Lu Yin , Jiajun Wu , Tong Zhang , Manling Li , Shiwei Liu

Emotion Recognition in Conversations (ERC) presents unique challenges, requiring models to capture the temporal flow of multi-turn dialogues and to effectively integrate cues from multiple modalities. We propose Mixture of Speech-Text…

Computation and Language · Computer Science 2026-02-27 Soumya Dutta , Smruthi Balaji , Sriram Ganapathy

In recent years, Mixture-of-Experts (MoE) has emerged as an effective approach for enhancing the capacity of deep neural network (DNN) with sub-linear computational costs. However, storing all experts on GPUs incurs significant memory…

Machine Learning · Computer Science 2025-03-11 Suraiya Tairin , Shohaib Mahmud , Haiying Shen , Anand Iyer

Medical vision-and-language pre-training provides a feasible solution to extract effective vision-and-language representations from medical images and texts. However, few studies have been dedicated to this field to facilitate medical…

Computer Vision and Pattern Recognition · Computer Science 2022-09-16 Zhihong Chen , Yuhao Du , Jinpeng Hu , Yang Liu , Guanbin Li , Xiang Wan , Tsung-Hui Chang

3D vision and spatial reasoning have long been recognized as preferable for accurately perceiving our three-dimensional world, especially when compared with traditional visual reasoning based on 2D images. Due to the difficulties in…

Computation and Language · Computer Science 2025-01-29 Yueen Ma , Yuzheng Zhuang , Jianye Hao , Irwin King

Mixture-of-Experts (MoE) models, the state-of-the-art in large-scale AI, achieve high quality by sparsely activating parameters. However, their reliance on routing between a few monolithic experts via a top-k mechanism creates a "quality…

Computation and Language · Computer Science 2025-10-23 Xinfeng Xia , Jiacheng Liu , Xiaofeng Hou , Peng Tang , Mingxuan Zhang , Wenfeng Wang , Chao Li

Computer vision researchers are embracing two promising paradigms: Vision Transformers (ViTs) and Multi-task Learning (MTL), which both show great performance but are computation-intensive, given the quadratic complexity of self-attention…

Hardware Architecture · Computer Science 2023-09-14 Rishov Sarkar , Hanxue Liang , Zhiwen Fan , Zhangyang Wang , Cong Hao

Concept bottleneck models are interpretable predictive models that are often used in domains where model trust is a key priority, such as healthcare. They identify a small number of human-interpretable concepts in the data, which they then…

Machine Learning · Computer Science 2024-12-25 Katrina Brown , Marton Havasi , Finale Doshi-Velez

Semi-supervised learning has been employed to alleviate the need for extensive labeled data for histopathology image segmentation, but existing methods struggle with noisy pseudo-labels due to ambiguous gland boundaries and morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Thien Nguyen , Daisuke Kihara , Tianyang Wang , Xingjian Li , Min Xu

In this study, we propose MoME, a Mixture of Visual Language Medical Experts, for Medical Image Segmentation. MoME adapts the successful Mixture of Experts (MoE) paradigm, widely used in Large Language Models (LLMs), for medical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Arghavan Rezvani , Xiangyi Yan , Anthony T. Wu , Kun Han , Pooya Khosravi , Xiaohui Xie