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Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Jian Yu , Joakim Nguyen , Jinrui Fang , Awais Naeem , Zeyuan Cao , Sanjay Krishnan , Nicholas Konz , Tianlong Chen , Chandra Krishnan , Hairong Wang , Edward Castillo , Ying Ding , Ankita Shukla

With growing demand for interpretability in deep learning, especially in high stakes domains, Concept Bottleneck Models (CBMs) address this by inserting human understandable concepts into the prediction pipeline, but they are generally…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Jiakai Lin , Jinchang Zhang , Guoyu Lu

Recent advancements in general-purpose or domain-specific multimodal large language models (LLMs) have witnessed remarkable progress for medical decision-making. However, they are designated for specific classification or generative tasks,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Songtao Jiang , Tuo Zheng , Yan Zhang , Yeying Jin , Li Yuan , Zuozhu Liu

Multi-modal 3D understanding is a fundamental task in computer vision. Previous multi-modal fusion methods typically employ a single, dense fusion network, struggling to handle the significant heterogeneity and complexity across modalities,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Yu Li , Yuenan Hou , Yingmei Wei , Xinge Zhu , Yuexin Ma , Wenqi Shao , Yanming Guo

Recent advancements in multimodal large language models (MLLMs) have demonstrated considerable potential for comprehensive 3D scene understanding. However, existing approaches typically utilize only one or a limited subset of 3D modalities,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Yue Zhang , Yingzhao Jian , Hehe Fan , Yi Yang , Roger Zimmermann

Large language models allocate uniform computation across all tokens, ignoring that some sequences are trivially predictable while others require deep reasoning. We introduce ConceptMoE, which dynamically merges semantically similar tokens…

Machine Learning · Computer Science 2026-01-30 Zihao Huang , Jundong Zhou , Xingwei Qu , Qiyang Min , Ge Zhang

Medical imaging data is inherently heterogeneous across different modalities and clinical centers, posing unique challenges for developing generalizable foundation models. Conventional entails training distinct models per dataset or using a…

Image and Video Processing · Electrical Eng. & Systems 2024-05-16 Yufeng Jiang , Yiqing Shen

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

Machine Learning · Computer Science 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Multimodal magnetic resonance imaging (MRI) provides complementary information for sub-region analysis of brain tumors. Plenty of methods have been proposed for automatic brain tumor segmentation using four common MRI modalities and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Hong Liu , Dong Wei , Donghuan Lu , Jinghan Sun , Liansheng Wang , Yefeng Zheng

The integration of multi-modal Magnetic Resonance Imaging (MRI) and clinical data holds great promise for enhancing the diagnosis of neurological disorders (NDs) in real-world clinical settings. Deep Learning (DL) has recently emerged as a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Wajih Hassan Raza , Aamir Bader Shah , Yu Wen , Yidan Shen , Juan Diego Martinez Lemus , Mya Caryn Schiess , Timothy Michael Ellmore , Renjie Hu , Xin Fu

Models based on human-understandable concepts have received extensive attention to improve model interpretability for trustworthy artificial intelligence in the field of medical image analysis. These methods can provide convincing…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Hongmei Wang , Junlin Hou , Hao Chen

Clinical decision-making reflects diverse strategies shaped by regional patient populations and institutional protocols. However, most existing medical artificial intelligence (AI) models are trained on highly prevalent data patterns, which…

Multiparametric 3D brain MRI (mpMRI) is central to neuroradiology, but producing tumor location, appearance, size, and involvement of critical structures for neurosurgical planning remains challenging. We introduce mpLLM, a multimodal LLM…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Arvind Murari Vepa , Yannan Yu , Jingru Gan , Anthony Cuturrufo , Michael F. Romano , Weikai Li , Fabien Scalzo , Wei Wang , Yizhou Sun

AI-based models for histopathology whole slide image (WSI) analysis are increasingly common, but unsharp or blurred areas within WSI can significantly reduce prediction performance. In this study, we investigated the effect of image blur on…

Image and Video Processing · Electrical Eng. & Systems 2025-07-21 Yujie Xiang , Bojing Liu , Mattias Rantalainen

Mixture-of-Experts (MoE) is a flexible framework that combines multiple specialized submodels (``experts''), by assigning covariate-dependent weights (``gating functions'') to each expert, and have been commonly used for analyzing…

Methodology · Statistics 2026-01-06 Qicheng Zhao , Celia M. T. Greenwood , Qihuang Zhang

Multimodal understanding of tables in real-world contexts is challenging due to the complexity of structure, symbolic density, and visual degradation (blur, skew, watermarking, incomplete structures or fonts, multi-span or hierarchically…

Artificial Intelligence · Computer Science 2025-06-27 Junwen Zhang , Pu Chen , Yin Zhang

Recent advancements in Multimodal Large Language Models (MLLMs) underscore the significance of scalable models and data to boost performance, yet this often incurs substantial computational costs. Although the Mixture of Experts (MoE)…

Artificial Intelligence · Computer Science 2024-05-21 Yunxin Li , Shenyuan Jiang , Baotian Hu , Longyue Wang , Wanqi Zhong , Wenhan Luo , Lin Ma , Min Zhang

Empowering Large Multimodal Models (LMMs) with image generation often leads to catastrophic forgetting in understanding tasks due to severe gradient conflicts. While existing paradigms like Mixture-of-Transformers (MoT) mitigate this…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Xiangyue Liu , Zijian Zhang , Miles Yang , Zhao Zhong , Liefeng Bo , Ping Tan

Foundation models for medical image segmentation have achieved remarkable performance. Adaptive fine-tuning of natural image segmentation foundation models is crucial for medical image segmentation tasks. However, some limitations exist in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Xinwei Zhang , Hu Chen , Zhe Yuan , Sukun Tian , Peng Feng

While medical Vision-Language models (VLMs) achieve strong performance on tasks such as tumor or organ segmentation and diagnosis prediction, their opaque latent representations limit clinical trust and the ability to explain predictions.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Md Rakibul Haque , KM Arefeen Sultan , Tushar Kataria , Shireen Elhabian
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