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Dynamic multiobjective optimization problems (DMOPs) feature time-varying objectives, which cause the Pareto optimal solution (POS) set to drift over time and make it difficult to maintain both convergence and diversity under limited…

Neural and Evolutionary Computing · Computer Science 2026-03-31 Jian Guan , Huolong Wu , Zhenzhong Wang , Gary G. Yen , Min Jiang

Multimodal Large Language Models (MLLMs) have demonstrated remarkable proficiency in diverse tasks across different domains, with an increasing focus on improving their zero-shot generalization capabilities for unseen multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Ying Shen , Zhiyang Xu , Qifan Wang , Yu Cheng , Wenpeng Yin , Lifu Huang

Rising costs in recent years of developing new drugs and treatments have led to extensive research in optimization techniques in biomolecular design. Currently, the most widely used approach in biomolecular design is directed evolution,…

Machine Learning · Computer Science 2021-11-09 Alexander Whatley , Zhekun Luo , Xiangru Tang

In LLM alignment and many other ML applications, one often faces the Multi-Objective Fine-Tuning (MOFT) problem, i.e., fine-tuning an existing model with datasets labeled w.r.t. different objectives simultaneously. To address the challenge,…

Machine Learning · Computer Science 2025-06-23 Yinuo Ren , Tesi Xiao , Michael Shavlovsky , Lexing Ying , Holakou Rahmanian

Aligning large language models (LLMs) with human preferences in federated learning (FL) is challenging due to decentralized, privacy-sensitive, and highly non-IID preference data. Direct Preference Optimization (DPO) offers an efficient…

Machine Learning · Computer Science 2026-03-23 Kewen Zhu , Liping Yi , Zhiming Zhao , Zhuang Qi , Han Yu , Qinghua Hu

Supervised fine-tuning (SFT) has become a crucial step for aligning pretrained large language models (LLMs) using supervised datasets of input-output pairs. However, despite being supervised, SFT is inherently limited by its generative…

Computation and Language · Computer Science 2025-07-25 Siqi Guo , Ilgee Hong , Vicente Balmaseda , Changlong Yu , Liang Qiu , Xin Liu , Haoming Jiang , Tuo Zhao , Tianbao Yang

Online and offline RLHF methods, such as PPO and DPO, have been highly successful in aligning AI with human preferences. Despite their success, however, these methods suffer from fundamental limitations: (a) Models trained with RLHF can…

Machine Learning · Computer Science 2025-04-15 Eugene Choi , Arash Ahmadian , Matthieu Geist , Oilvier Pietquin , Mohammad Gheshlaghi Azar

Aligning large language models (LLMs) with human values and safety constraints is challenging, especially when objectives like helpfulness, truthfulness, and avoidance of harm conflict. Reinforcement Learning from Human Feedback (RLHF) has…

Computation and Language · Computer Science 2025-03-31 Xuying Li , Zhuo Li , Yuji Kosuga , Victor Bian

Diffusion-based models are recognized for their effectiveness in using real-world driving data to generate realistic and diverse traffic scenarios. These models employ guided sampling to incorporate specific traffic preferences and enhance…

Machine Learning · Computer Science 2025-02-19 Seungjun Yu , Kisung Kim , Daejung Kim , Haewook Han , Jinhan Lee

A preference based multi-objective evolutionary algorithm is proposed for generating solutions in an automatically detected knee point region. It is named Automatic Preference based DI-MOEA (AP-DI-MOEA) where DI-MOEA stands for…

Neural and Evolutionary Computing · Computer Science 2021-01-26 Yali Wang , Steffen Limmer , Markus Olhofer , Michael Emmerich , Thomas Baeck

Diffusion models have achieved impressive results in generative tasks such as text-to-image synthesis, yet they often struggle to fully align outputs with nuanced user intent and maintain consistent aesthetic quality. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Dohyun Kim , Seungwoo Lyu , Seung Wook Kim , Paul Hongsuck Seo

Large Language Models (LLMs) have become pivotal in advancing natural language processing, yet their potential to perpetuate biases poses significant concerns. This paper introduces a new framework employing Direct Preference Optimization…

Computation and Language · Computer Science 2024-07-22 Ahmed Allam

Recent advances in diffusion models have improved Real-World Image Super-Resolution (Real-ISR), but existing methods lack human feedback integration, risking misalignment with human preference and may leading to artifacts, hallucinations…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Miaomiao Cai , Simiao Li , Wei Li , Xudong Huang , Hanting Chen , Jie Hu , Yunhe Wang

This study evaluates Direct Preference Optimization (DPO) and its variants for aligning Large Language Models (LLMs) with human preferences, testing three configurations: (1) with Supervised Fine Tuning (SFT), (2) without SFT, and (3)…

Computation and Language · Computer Science 2025-02-11 Amir Saeidi , Shivanshu Verma , Md Nayem Uddin , Chitta Baral

Preference Optimization (PO), is gaining popularity as an alternative choice of Proximal Policy Optimization (PPO) for aligning Large Language Models (LLMs). Recent research on aligning LLMs iteratively with synthetic or partially synthetic…

Computation and Language · Computer Science 2024-09-16 Yaojie Shen , Xinyao Wang , Yulei Niu , Ying Zhou , Lexin Tang , Libo Zhang , Fan Chen , Longyin Wen

The accurate prediction of protein-RNA binding affinity remains an unsolved problem in structural biology, limiting opportunities in understanding gene regulation and designing RNA-targeting therapeutics. A central obstacle is the…

Directed evolution is a versatile technique in protein engineering that mimics the process of natural selection by iteratively alternating between mutagenesis and screening in order to search for sequences that optimize a given property of…

Biomolecules · Quantitative Biology 2024-05-02 Lixue Cheng , Ziyi Yang , Changyu Hsieh , Benben Liao , Shengyu Zhang

Aligning the output of Large Language Models (LLMs) with human preferences (e.g., by means of reinforcement learning with human feedback, or RLHF) is essential for ensuring their effectiveness in real-world scenarios. Despite significant…

Artificial Intelligence · Computer Science 2024-10-23 Pietro Bernardelle , Gianluca Demartini

Without using explicit reward, direct preference optimization (DPO) employs paired human preference data to fine-tune generative models, a method that has garnered considerable attention in large language models (LLMs). However, exploration…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Yunhong Lu , Qichao Wang , Hengyuan Cao , Xierui Wang , Xiaoyin Xu , Min Zhang

Direct Preference Optimisation (DPO) has emerged as a powerful method for aligning Large Language Models (LLMs) with human preferences, offering a stable and efficient alternative to approaches that use Reinforcement learning via Human…

Artificial Intelligence · Computer Science 2025-05-06 Sarvesh Shashidhar , Ritik , Nachiketa Patil , Suraj Racha , Ganesh Ramakrishnan
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