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Learning how to do things from trial and error in real time is a hallmark of biological intelligence, yet most LLM-based agents lack mechanisms to acquire procedural knowledge after deployment. We propose Procedural Recall for Agents with…

Artificial Intelligence · Computer Science 2026-04-24 Dasheng Bi , Yubin Hu , Mohammed N. Nasir

Explanations for AI models in high-stakes domains like medicine often lack verifiability, which can hinder trust. To address this, we propose an interactive agent that produces explanations through an auditable sequence of actions. The…

Artificial Intelligence · Computer Science 2025-11-04 Yuhang Huang , Zekai Lin , Fan Zhong , Lei Liu

Corpus distillation for biomedical large language models (LLMs) seeks to address the pressing challenge of insufficient quantity and quality in open-source annotated scientific corpora, which remains a bottleneck for effective LLM training…

Computation and Language · Computer Science 2025-12-19 Meng Xiao , Xunxin Cai , Qingqing Long , Chengrui Wang , Yuanchun Zhou , Hengshu Zhu

This paper details two novel frameworks for developing autonomous, agentic AI in scientific workflows. Both systems leverage a hybrid Local Body, Remote Brain architecture via Google Colab, utilizing Python-based local orchestrators to…

Artificial Intelligence · Computer Science 2026-05-27 Judy Fox , Geoffrey Fox

Large language models (LLMs) have grown in their usage to provide support for question answering across numerous disciplines. The models on their own have already shown promise for answering basic questions, however fail quickly where…

Information Retrieval · Computer Science 2025-04-15 David Brett , Anniek Myatt

Artificial intelligence systems are transforming scientific discovery by accelerating specific research tasks, from protein structure prediction to materials design, yet remain confined to narrow domains requiring substantial human…

Artificial Intelligence · Computer Science 2026-01-30 Gabrielle Wehr , Reuben Rideaux , Amaya J. Fox , David R. Lightfoot , Jason Tangen , Jason B. Mattingley , Shane E. Ehrhardt

Artificial intelligence (AI) agents are emerging as transformative tools in drug discovery, with the ability to autonomously reason, act, and learn through complicated research workflows. Building on large language models (LLMs) coupled…

Artificial intelligence systems for scientific discovery have demonstrated remarkable potential, yet existing approaches remain largely proprietary and operate in batch-processing modes requiring hours per research cycle, precluding…

Artificial Intelligence · Computer Science 2026-01-28 Lukas Weidener , Marko Brkić , Mihailo Jovanović , Ritvik Singh , Chiara Baccin , Emre Ulgac , Alex Dobrin , Aakaash Meduri

Reproducing computational research is often assumed to be as simple as rerunning the original code with provided data. In practice, missing packages, fragile file paths, version conflicts, or incomplete logic frequently cause analyses to…

Software Engineering · Computer Science 2026-04-24 Syed Mehtab Hussain Shah , Frank Hopfgartner , Arnim Bleier

We envision "AI scientists" as systems capable of skeptical learning and reasoning that empower biomedical research through collaborative agents that integrate AI models and biomedical tools with experimental platforms. Rather than taking…

Keeping pace with the rapid growth of academia literature presents a significant challenge for researchers, funding bodies, and academic societies. To address the time-consuming manual effort required for scholarly discovery, we present a…

Machine Learning · Computer Science 2025-09-15 Om Vishesh , Harshad Khadilkar , Deepak Akkil

Automating science laboratories enables faster, safer, more accurate, and more reproducible execution of protocols, accelerating the discovery and testing of new materials, drugs, and more. However, setting up and running autonomous labs…

Artificial Intelligence · Computer Science 2026-05-19 Angelos Angelopoulos , James F. Cahoon , Ron Alterovitz

With recent and rapid advancements in artificial intelligence (AI), understanding the foundation of purposeful behaviour in autonomous agents is crucial for developing safe and efficient systems. While artificial neural networks have…

Artificial Intelligence · Computer Science 2025-08-12 Aswin Paul , Moein Khajehnejad , Forough Habibollahi , Brett J. Kagan , Adeel Razi

Background: Large language models are typically evaluated as models, benchmarks, or short conversational episodes. Less is known about what happens when an agent is embedded persistently in a real academic research environment with durable…

Multiagent Systems · Computer Science 2026-05-27 Anas H. Alzahrani

As large language models increasingly mediate firm - customer interactions, firms face a tradeoff: the most capable models perform well but are costly and difficult to control at scale. Existing knowledge distillation methods address this…

Computation and Language · Computer Science 2026-02-23 Tong Wang , K. Sudhir

Modern science is reaching a critical inflection point. Instruments across disciplines, from particle physics and astronomy to genomics and climate modeling, now produce data of such scale, diversity, and interdependence that traditional…

High Energy Physics - Experiment · Physics 2026-03-10 Ke Li , Beijiang Liu , Bruce Mellado , Changzheng Yuan , Zhengde Zhang

Machine learning has emerged as a powerful tool for scientific discovery, enabling researchers to extract meaningful insights from complex datasets. For instance, it has facilitated the identification of disease-predictive genes from gene…

Artificial Intelligence is rapidly advancing and radically impacting everyday life, driven by the increasing availability of computing power. Despite this trend, the adoption of AI in real-world healthcare is still limited. One of the main…

Artificial Intelligence · Computer Science 2024-12-02 Akshat Dubey , Zewen Yang , Georges Hattab

Generative AI agents in life sciences face a critical challenge: determining the optimal approach for diverse queries ranging from simple factoid questions to complex mechanistic reasoning. Traditional methods rely on fixed rules or…

Machine Learning · Computer Science 2025-12-04 Nihir Chadderwala

Recent advances in agentic AI have enabled increasingly autonomous workflows, but existing systems still face substantial challenges in achieving reliable deployment in real-world scientific research. In this work, we present a safe,…

Artificial Intelligence · Computer Science 2026-04-16 Qibin Liu , Julia Gonski
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