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General Multimodal Large Language Models (MLLMs) often underperform in capturing domain-specific nuances in medical diagnosis, trailing behind fully supervised baselines. Although fine-tuning provides a remedy, the high costs of expert…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Wenkai Zhao , Zipei Wang , Mengjie Fang , Di Dong , Jie Tian , Lingwei Zhang

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

LLM-based agents have been extensively applied across various domains, where memory stands out as one of their most essential capabilities. Previous memory mechanisms of LLM-based agents are manually predefined by human experts, leading to…

Machine Learning · Computer Science 2025-08-26 Zeyu Zhang , Quanyu Dai , Rui Li , Xiaohe Bo , Xu Chen , Zhenhua Dong

Deep search has recently emerged as a promising paradigm for enabling agents to retrieve fine-grained historical information without heavy memory pre-managed. However, existing deep search agents for memory system repeat past error…

Computation and Language · Computer Science 2026-05-14 Xinyuan Wang , Wenyu Mao , Junkang Wu , Xiang Wang , Xiangnan He

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Computation and Language · Computer Science 2024-10-31 Yubin Kim , Chanwoo Park , Hyewon Jeong , Yik Siu Chan , Xuhai Xu , Daniel McDuff , Hyeonhoon Lee , Marzyeh Ghassemi , Cynthia Breazeal , Hae Won Park

Medical Vision-Language Models (Med-VLMs) have achieved expert-level proficiency in interpreting diagnostic imaging. However, current models are predominantly trained on professional literature, limiting their ability to communicate…

Computation and Language · Computer Science 2026-04-08 Han Jang , Junhyeok Lee , Heeseong Eum , Kyu Sung Choi

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Vision-language models (VLMs) have shown promise in 2D medical image analysis, but extending them to 3D remains challenging due to the high computational demands of volumetric data and the difficulty of aligning 3D spatial features with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yu Xin , Gorkem Can Ates , Kuang Gong , Wei Shao

Large Language Models have revolutionized interactive applications; however, their finite context windows pose a critical data management challenge for maintaining stateful, long-term interactions. Existing memory approaches often rely on…

Artificial Intelligence · Computer Science 2026-05-29 Jiajie Fu , Junwen Chen , Mengzhao Wang , Aoxiang He , Maojia Sheng , Xiangyu Ke , Yifan Zhu , Yunjun Gao

Despite significant advancements in large language models (LLMs), the rapid and frequent integration of small-scale experiences, such as interactions with surrounding objects, remains a substantial challenge. Two critical factors in…

Computation and Language · Computer Science 2025-02-24 Yu Wang , Xinshuang Liu , Xiusi Chen , Sean O'Brien , Junda Wu , Julian McAuley

Memory-augmented LLM agents offer an appealing shortcut to continual learning: rather than updating model parameters, they accumulate experience in external memory, seemingly sidestepping the stability-plasticity dilemma of parametric…

Machine Learning · Computer Science 2026-05-01 Qisheng Hu , Quanyu Long , Wenya Wang

Large language model (LLM) agents accumulate rich episodic trajectories while solving real-world tasks, but it remains unclear whether such experience can be distilled into reusable procedural skills. We introduce SkillEvolBench, a…

Mixture-of-Experts (MoE) language models organize knowledge into explicitly routed expert modules, making expert-level representations traceable and analyzable. By analyzing expert activation patterns in MoE large language models (LLMs), we…

Computation and Language · Computer Science 2026-05-12 Chang Liu , Boyu Shi , Xu Yang , Xin Geng

Video Large Language Models (Video-LLMs) have shown strong video understanding, yet their application to long-form videos remains constrained by limited context windows. A common workaround is to compress long videos into a handful of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Yun Wang , Long Zhang , Jingren Liu , Jiaqi Yan , Zhanjie Zhang , Jiahao Zheng , Ao Ma , Run Ling , Xun Yang , Dapeng Wu , Xiangyu Chen , Xuelong Li

Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…

Computation and Language · Computer Science 2026-04-29 Jianghang Lin , Haihua Yang , Deli Yu , Kai Wu , Kai Ye , Jinghao Lin , Zihan Wang , Yuhang Wu , Liujuan Cao

The rapid evolution of neural architectures - from multilayer perceptrons to large-scale Transformer-based models - has enabled language models (LLMs) to exhibit emergent agentic behaviours when equipped with memory, planning, and external…

Artificial Intelligence · Computer Science 2025-09-22 Andrejs Sorstkins , Josh Bailey , Dr Alistair Baron

Molecular design involves an enormous and irregular search space, where traditional optimizers such as Bayesian optimization, genetic algorithms, and generative models struggle to leverage expert knowledge or handle complex feedback.…

Machine Learning · Computer Science 2025-12-09 Nian Ran , Yue Wang , Xiaoyuan Zhang , Zhongzheng Li , Qingsong Ran , Wenhao Li , Richard Allmendinger

Existing memory-augmented LLM agents often treat memory as a static repository with pre-defined representations and fixed retrieval pipelines, which is brittle in dynamic agentic environments where feedback, task variation, and…