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Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

The application of the Multi-modal Large Language Models (MLLMs) in medical clinical scenarios remains underexplored. Previous benchmarks only focus on the capacity of the MLLMs in medical visual question-answering (VQA) or report…

Computation and Language · Computer Science 2024-08-19 Hongcheng Liu , Yusheng Liao , Siqv Ou , Yuhao Wang , Heyang Liu , Yanfeng Wang , Yu Wang

Recent studies show that deep learning models achieve good performance on medical imaging tasks such as diagnosis prediction. Among the models, multimodality has been an emerging trend, integrating different forms of data such as chest…

Machine Learning · Computer Science 2022-02-10 Haodi Zhang , Chenyu Xu , Peirou Liang , Ke Duan , Hao Ren , Weibin Cheng , Kaishun Wu

Large language model (LLM) agents still struggle with long-term memory question answering, where answer-supporting evidence is often scattered across long conversational histories and buried in substantial irrelevant content. Existing…

Computation and Language · Computer Science 2026-05-22 Jianing Yin , Tan Tang

Cognitive decline often surfaces in language years before diagnosis. It is frequently non-experts, such as those closest to the patient, who first sense a change and raise concern. As LLMs become integrated into daily communication and used…

Computation and Language · Computer Science 2025-05-20 Lotem Peled-Cohen , Maya Zadok , Nitay Calderon , Hila Gonen , Roi Reichart

Despite significant progress in Vision-Language Pre-training (VLP), current approaches predominantly emphasize feature extraction and cross-modal comprehension, with limited attention to generating or transforming visual content. This gap…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Ziyang Zhang , Yang Yu , Yucheng Chen , Xulei Yang , Si Yong Yeo

Long-horizon language agents must operate under limited runtime memory, yet existing memory mechanisms often organize experience around descriptive criteria such as relevance, salience, or summary quality. For an agent, however, memory is…

Artificial Intelligence · Computer Science 2026-05-12 Mingxi Zou , Zhihan Guo , Langzhang Liang , Zhuo Wang , Qifan Wang , Qingsong Wen , Irwin King , Lizhen Qu , Zenglin Xu

A core challenge for faithful LLM role-playing is sustaining consistent characterization throughout long, open-ended dialogues, as models frequently fail to recall and accurately apply their designated persona knowledge without explicit…

Computation and Language · Computer Science 2026-03-23 Kai Wang , Haoyang You , Yang Zhang , Zhongjie Wang

Evidence-based medicine (EBM) plays a crucial role in the application of large language models (LLMs) in healthcare, as it provides reliable support for medical decision-making processes. Although it benefits from current…

Computation and Language · Computer Science 2025-03-24 Chengfeng Dou , Ying Zhang , Zhi Jin , Wenpin Jiao , Haiyan Zhao , Yongqiang Zhao , Zhengwei Tao

When addressing professional questions in the biomedical domain, humans typically acquire multiple pieces of information as evidence and engage in multifaceted analysis to provide high-quality answers. Current LLM-based question answering…

Computation and Language · Computer Science 2025-09-03 Chang Zong , Jian Wan , Siliang Tang , Lei Zhang

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Medical AI systems face two fundamental limitations. First, conventional vision-language models (VLMs) perform single-pass inference, yielding black-box predictions that cannot be audited or explained in clinical terms. Second, iterative…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Nicanor Mayumu , Zeenath Khan , Melodena Stephens , Patrick Mukala , Farhad Oroumchian

Long-term conversational memory requires retrieving evidence scattered across multiple sessions, yet single-pass retrieval fails on temporal and multi-hop questions. Existing iterative methods refine queries via generated content or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Yuyang Li , Yime He , Zeyu Zhang , Dong Gong

Current multimodal survival prediction methods typically rely on pathology images (WSIs) and genomic data, both of which are high-dimensional and redundant, making it difficult to extract discriminative features from them and align…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Chenyu Zhao , Yingxue Xu , Fengtao Zhou , Yihui Wang , Hao Chen

Medical large vision-language Models (Med-LVLMs) have shown promise in clinical applications but suffer from factual inaccuracies and unreliable outputs, posing risks in real-world diagnostics. While RAG has emerged as a potential solution,…

Computation and Language · Computer Science 2026-05-05 Zhe Chen , Yusheng Liao , Zhiyuan Zhu , Haolin Li , Hongcheng Liu , Yanfeng Wang , Yu Wang

Generating radiology reports automatically reduces the workload of radiologists and helps the diagnoses of specific diseases. Many existing methods take this task as modality transfer process. However, since the key information related to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yitian Tao , Liyan Ma , Jing Yu , Han Zhang

Personalized and continuous interactions are critical for LLM-based conversational agents, yet finite context windows and static parametric memory hinder the modeling of long-term, cross-session user states. Existing approaches, including…

Artificial Intelligence · Computer Science 2026-02-03 Ao Tian , Yunfeng Lu , Xinxin Fan , Changhao Wang , Lanzhi Zhou , Yeyao Zhang , Yanfang Liu

Large-scale pre-trained models, such as Vision Foundation Models (VFMs), have demonstrated impressive performance across various downstream tasks by transferring generalized knowledge, especially when target data is limited. However, their…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Pengchen Liang , Haishan Huang , Bin Pu , Jianguo Chen , Xiang Hua , Jing Zhang , Weibo Ma , Zhuangzhuang Chen , Yiwei Li , Qing Chang

Medical vision-language segmentation models suffer from catastrophic forgetting when adapting to new anatomical structures, requiring complete retraining that limits their clinical deployment. Although continual learning approaches have…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Ziyuan Gao

Large Language Models (LLMs) have shown impressive capabilities in generating human-like responses. However, their lack of domain-specific knowledge limits their applicability in healthcare settings, where contextual and comprehensive…

Computation and Language · Computer Science 2024-03-14 Subash Neupane , Shaswata Mitra , Sudip Mittal , Noorbakhsh Amiri Golilarz , Shahram Rahimi , Amin Amirlatifi
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