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Electronic Health Records (EHRs) enable deep learning for clinical predictions, but the optimal method for representing patient data remains unclear due to inconsistent evaluation practices. We present the first systematic benchmark to…
A great deal of effort has been devoted to discovering a particular genetic disorder, but its classification across a broad spectrum of disorder classes and types remains elusive. Early diagnosis of genetic disorders enables timely…
The COVID-19 pandemic has caused devastating economic and social disruption, straining the resources of healthcare institutions worldwide. This has led to a nationwide call for models to predict hospitalization and severe illness in…
Medical applications of machine learning (ML) have experienced a surge in popularity in recent years. The intensive care unit (ICU) is a natural habitat for ML given the abundance of available data from electronic health records. Models…
This study investigates the spatial integration of agent-based models (ABMs) and compartmental models for infectious disease modeling, presenting a novel hybrid approach and examining its implications. ABMs offer detailed insights by…
Antimicrobial resistance (AMR) threatens global health. A promising and underexplored strategy to tackle this problem is sequential therapies exploiting collateral sensitivity (CS), whereby resistance to one drug increases sensitivity to…
Windowing is a common technique in EEG machine learning classification and other time series tasks. However, a challenge arises when employing this technique: computational expense inhibits learning global relationships across an entire…
Current machine learning models aiming to predict sepsis from Electronic Health Records (EHR) do not account for the heterogeneity of the condition, despite its emerging importance in prognosis and treatment. This work demonstrates the…
Many economies are challenged by the effects of an ageing population, particularly in sectors where resource capacity planning is critical, such as healthcare. This research addresses the operational challenges of bed and staffing capacity…
Many practical applications of AI in medicine consist of semi-supervised discovery: The investigator aims to identify features of interest at a resolution more fine-grained than that of the available human labels. This is often the scenario…
Epidemiologists use a variety of statistical algorithms for the early detection of outbreaks. The practical usefulness of such methods highly depends on the trade-off between the detection rate of outbreaks and the chances of raising a…
Early identification of intensive care patients at risk of in-hospital mortality enables timely intervention and efficient resource allocation. Despite high predictive performance, existing machine learning approaches lack transparency and…
The persistent battle to decrease childhood mortality serves as a commonly employed benchmark for gauging advancements in the field of medicine. Globally, the under-5 mortality rate stands at approximately 5 million, with a significant…
Heart attack remain one of the greatest contributors to mortality in the United States and globally. Patients admitted to the intensive care unit (ICU) with diagnosed heart attack (myocardial infarction or MI) are at higher risk of death.…
Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…
In the emerging era of big data, larger available clinical datasets and computational advances have sparked a massive interest in machine learning-based approaches. The number of manuscripts related to machine learning or artificial…
The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…
Mammography, an X-ray-based imaging technique, remains central to the early detection of breast cancer. Recent advances in artificial intelligence have enabled increasingly sophisticated computer-aided diagnostic methods, evolving from…
Vital signs are crucial in intensive care units (ICUs). They are used to track the patient's state and to identify clinically significant changes. Predicting vital sign trajectories is valuable for early detection of adverse events.…
Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models…