Related papers: bioETH-PRS: Confidential Polygenic Risk Scoring wi…
Genome-wide association studies are pivotal in understanding the genetic underpinnings of complex traits and diseases. Collaborative, multi-site GWAS aim to enhance statistical power but face obstacles due to the sensitive nature of genomic…
With the promise of greater decentralization and sustainability, Ethereum transitioned from a Proof-of-Work (PoW) to a Proof-of-Stake (PoS) consensus mechanism. The new consensus protocol introduces novel vulnerabilities that warrant…
Objective: SNP heritability estimates vary substantially across estimation strategies, yet the downstream consequences for polygenic risk score (PRS) construction remain poorly characterised. We systematically benchmarked heritability…
Traditionally, threshold secret sharing (TSS) schemes assume all parties have equal weight, yet emerging systems like blockchains reveal disparities in party trustworthiness, such as stake or reputation. Weighted Secret Sharing (WSS)…
Current blockchain consensus protocols -- notably, Proof of Work (PoW) and Proof of Stake (PoS) -- deliver global agreement but exhibit structural constraints. PoW anchors security in heavy computation, inflating energy use and imposing…
Proof of Stake (PoS) blockchains offer promising alternatives to traditional Proof of Work (PoW) systems, providing scalability and energy efficiency. However, blockchains operate in a decentralized manner and the network is composed of…
We present automatically parameterised Fully Homomorphic Encryption (FHE) for encrypted neural network inference and exemplify our inference over FHE compatible neural networks with our own open-source framework and reproducible examples.…
Threshold fully homomorphic encryption (ThFHE) enables multiple parties to compute functions over their sensitive data without leaking data privacy. Most of existing ThFHE schemes are restricted to full threshold and require the…
Like any other useful technology, cryptocurrencies are sometimes used for criminal activities. While transactions are recorded on the blockchain, there exists a need for a more rapid and scalable method to detect addresses associated with…
In recent years, smart contracts have suffered major exploits, costing millions of dollars. Unlike traditional programs, smart contracts are deployed on a blockchain. As such, they cannot be modified once deployed. Though various tools have…
In this paper, we propose a trust-centric privacy-preserving blockchain for dynamic spectrum access in IoT networks. To be specific, we propose a trust evaluation mechanism to evaluate the trustworthiness of sensing nodes and design a…
In today's connected world, resource constrained devices are deployed for sensing and decision making applications, ranging from smart cities to environmental monitoring. Those recourse constrained devices are connected to create real-time…
With the proliferation of intelligent healthcare systems, patients' Personal Health Records (PHR) generated by the Internet of Medical Things (IoMT) in real-time play a vital role in disease diagnosis. The integration of emerging blockchain…
Many Ethereum smart contracts rely on block attributes such as block.timestamp or blockhash to generate random numbers for applications like lotteries and games. However, these values are predictable and miner-manipulable, creating the Bad…
The growing utilization of Internet of Medical Things (IoMT) devices, including smartwatches and wearable medical devices, has facilitated real-time health monitoring and data analysis to enhance healthcare outcomes. These gadgets…
Ethereum 2.0, as the preeminent smart contract blockchain platform, guarantees the precise execution of applications without third-party intervention. At its core, this system leverages the Proof-of-Stake (PoS) consensus mechanism, which…
Designing an efficient difficulty control algorithm is an essential problem in Proof-of-Work (PoW) based blockchains because the network hash rate is randomly changing. This paper proposes a general difficulty control algorithm and provides…
Decentralized identity systems promise user-controlled identifiers and cross-domain verification without a shared identity provider, yet authentication still reduces to possession of keys or credentials once secrets are leaked, reused, or…
As of July 15, 2023, Ethererum, which is a Proof-of-Stake (PoS) blockchain [1] has around 410 Billion USD in total assets on chain (popularly referred to as total-value-locked, TVL) but has only 33 Billion USD worth of ETH staked in…
Academic examination systems worldwide continue to rely on centralised, opaque record-keeping that is often vulnerable to credential forgery, result tampering, examiner bias, and the absence of transparent re-evaluation pathways. Existing…