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Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…
Large Language Models have seen expanding application across domains, yet their effectiveness as assistive tools for scientific writing - an endeavor requiring precision, multimodal synthesis, and domain expertise - remains insufficiently…
Question answering (QA) systems for large document collections typically use pipelines that (i) retrieve possibly relevant documents, (ii) re-rank them, (iii) rank paragraphs or other snippets of the top-ranked documents, and (iv) select…
Information retrieval (IR) is essential in search engines and dialogue systems as well as natural language processing tasks such as open-domain question answering. IR serve an important function in the biomedical domain, where content and…
Effective biomedical literature retrieval (BLR) plays a central role in precision medicine informatics. In this paper, we propose GRAPHENE, which is a deep learning based framework for precise BLR. GRAPHENE consists of three main different…
Retrieval-augmented generation (RAG) enhances large language models (LLMs) by retrieving relevant documents from external sources and incorporating them into the context. While it improves reliability by providing factual texts, it…
Pretrained language models have served as important backbones for natural language processing. Recently, in-domain pretraining has been shown to benefit various domain-specific downstream tasks. In the biomedical domain, natural language…
Retrieval-Augmented Generation (RAG) systems traditionally treat retrieval and generation as separate processes, requiring explicit textual queries to connect them. This separation can limit the ability of models to generalize across…
Biomedical literature and clinical narratives pose multifaceted challenges for natural language understanding, from precise entity extraction and document synthesis to multi-step diagnostic reasoning. This study extends a unified benchmark…
Medical vision-language models (VLMs) offer promise for clinical decision support, yet their reliability under distribution shifts remains a major concern for safe deployment. These models often learn task-agnostic correlations due to…
The availability of biomedical text data and advances in natural language processing (NLP) have made new applications in biomedical NLP possible. Language models trained or fine tuned using domain specific corpora can outperform general…
Clinical decision-making requires synthesizing heterogeneous evidence, including patient histories, clinical guidelines, and trajectories of comparable cases. While large language models (LLMs) offer strong reasoning capabilities, they…
Purpose: To develop and evaluate an automated system for extracting structured clinical information from unstructured radiology and pathology reports using open-weights large language models (LMs) and retrieval augmented generation (RAG),…
Deep Research Agents (DRAs) generate citation-rich reports via multi-step search and synthesis, yet existing benchmarks mainly target text-only settings or short-form multimodal QA, missing end-to-end multimodal evidence use. We introduce…
Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based…
Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…
Protein-Text Question Answering (QA) is crucial for interpreting biological sequences through natural language. The integration of Large Language Models (LLMs) with Retrieval-Augmented Generation (RAG) that efficiently leverages biological…
Recent advancements in Large Language Models (LLMs) have significantly improved their performance across various Natural Language Processing (NLP) tasks. However, LLMs still struggle with generating non-factual responses due to limitations…
Adverse drug reactions / events (ADR/ADE) have a major impact on patient health and health care costs. Detecting ADR's as early as possible and sharing them with regulators, pharma companies, and healthcare providers can prevent morbidity…
This paper proposes a medical literature summary generation method based on the BERT model to address the challenges brought by the current explosion of medical information. By fine-tuning and optimizing the BERT model, we develop an…