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Recent advances in deep research systems enable large language models to retrieve, synthesize, and reason over large-scale external knowledge. In medicine, developing clinical guidelines critically depends on such deep evidence integration.…

HealthBench, a benchmark designed to measure the capabilities of AI systems for health better (Arora et al., 2025), has advanced medical language model evaluation through physician-crafted dialogues and transparent rubrics. However, its…

Artificial Intelligence · Computer Science 2025-08-04 Fred Mutisya , Shikoh Gitau , Nasubo Ongoma , Keith Mbae , Elizabeth Wamicha

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Clinical notes containing valuable patient information are written by different health care providers with various scientific levels and writing styles. It might be helpful for clinicians and researchers to understand what information is…

Computation and Language · Computer Science 2023-03-17 Hoda Memarzadeh , Nasser Ghadiri , Matthias Samwald , Maryam Lotfi Shahreza

The text of clinical notes can be a valuable source of patient information and clinical assessments. Historically, the primary approach for exploiting clinical notes has been information extraction: linking spans of text to concepts in a…

Computation and Language · Computer Science 2019-06-11 Sarah Wiegreffe , Edward Choi , Sherry Yan , Jimeng Sun , Jacob Eisenstein

Large language models (LLMs) show promise for extracting clinically meaningful information from unstructured health records, yet their translation into real-world settings is constrained by the lack of scalable and trustworthy validation…

Unstructured information comprises a valuable source of data in clinical records. For text mining in clinical records, concept extraction is the first step in finding assertions and relationships. This study presents a system developed for…

Information Retrieval · Computer Science 2010-12-09 Ning Kang , Rogier Barendse , Zubair Afzal , Bharat Singh , Martijn J. Schuemie , Erik M. van Mulligen , Jan A. Kors

Medical coding, the translation of unstructured clinical text into standardized medical codes, is a crucial but time-consuming healthcare practice. Though large language models (LLM) could automate the coding process and improve the…

Computation and Language · Computer Science 2025-03-25 John Wu , David Wu , Jimeng Sun

Large language models (LLMs) have demonstrated promising performance on medical benchmarks; however, their ability to perform medical calculations, a crucial aspect of clinical decision-making, remains underexplored and poorly evaluated.…

Computation and Language · Computer Science 2026-02-03 Benlu Wang , Iris Xia , Yifan Zhang , Junda Wang , Feiyun Ouyang , Shuo Han , Arman Cohan , Hong Yu , Zonghai Yao

The field of healthcare has increasingly turned its focus towards Large Language Models (LLMs) due to their remarkable performance. However, their performance in actual clinical applications has been underexplored. Traditional evaluations…

Large Language Models (LLMs) have advanced Table Question Answering, where most queries can be answered by extracting information or simple aggregation. However, a common class of real-world queries is implicitly predictive, requiring the…

Computation and Language · Computer Science 2026-05-01 An-Yang Ji , Jun-Peng Jiang , De-Chuan Zhan , Han-Jia Ye

While Large Language Models (LLMs) excel on standardized medical exams, high scores often fail to translate to high-quality responses for real-world medical queries. Current evaluations rely heavily on multiple-choice questions, failing to…

Visual markups such as highlights, underlines, and bold text are common in table-centric documents. Although multimodal large language models (MLLMs) have made substantial progress in document understanding, their ability to treat such cues…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Lexin Wang , Shenghua Liu , Yiwei Wang , Yujun Cai , Yuyao Ge , Jiayu Yao , Jiafeng Guo , Xueqi Cheng

Background Concept extraction, a subdomain of natural language processing (NLP) with a focus on extracting concepts of interest, has been adopted to computationally extract clinical information from text for a wide range of applications…

Electronic health records (EHR) contain large volumes of unstructured text, requiring the application of Information Extraction (IE) technologies to enable clinical analysis. We present the open-source Medical Concept Annotation Toolkit…

Medical large language models (LLMs) research often makes bold claims, from encoding clinical knowledge to reasoning like a physician. These claims are usually backed by evaluation on competitive benchmarks; a tradition inherited from…

Computation and Language · Computer Science 2025-03-17 Ahmed Alaa , Thomas Hartvigsen , Niloufar Golchini , Shiladitya Dutta , Frances Dean , Inioluwa Deborah Raji , Travis Zack

As large language models (LLMs) develop increasingly sophisticated capabilities and find applications in medical settings, it becomes important to assess their medical safety due to their far-reaching implications for personal and public…

Artificial Intelligence · Computer Science 2024-10-11 Tessa Han , Aounon Kumar , Chirag Agarwal , Himabindu Lakkaraju

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Medical Large Language Models (MLLMs) have demonstrated potential in healthcare applications, yet their propensity for hallucinations -- generating medically implausible or inaccurate information -- presents substantial risks to patient…

Computation and Language · Computer Science 2025-04-01 Kaiwen Zuo , Yirui Jiang