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A physics-informed neural network (PINN) embedded with the susceptible-infected-removed (SIR) model is devised to understand the temporal evolution dynamics of infectious diseases. Firstly, the effectiveness of this approach is demonstrated…

Quantitative Methods · Quantitative Biology 2025-04-08 Shuai Han , Lukas Stelz , Horst Stoecker , Lingxiao Wang , Kai Zhou

Compartmental models provide simple and efficient tools to analyze the relevant transmission processes during an outbreak, to produce short-term forecasts or transmission scenarios, and to assess the impact of vaccination campaigns.…

Numerical Analysis · Mathematics 2025-02-19 Caterina Millevoi , Damiano Pasetto , Massimiliano Ferronato

This work introduces a physics-informed neural networks (PINNs)-based model predictive control (MPC) framework for susceptible-infected-recovered ($SIR$) spreading models. Existing studies in MPC design for epidemic control often assume…

Machine Learning · Computer Science 2025-09-17 Aiping Zhong , Baike She , Philip E. Paré

Physics-informed neural networks (PINNs) have great potential for flexibility and effectiveness in forward modeling and inversion of seismic waves. However, coordinate-based neural networks (NNs) commonly suffer from the "spectral bias"…

Geophysics · Physics 2025-06-19 Yi Ding , Su Chen , Hiroe Miyake , Xiaojun Li

Forecasting temporal processes such as virus spreading in epidemics often requires more than just observed time-series data, especially at the beginning of a wave when data is limited. Traditional methods employ mechanistic models like the…

Artificial Intelligence · Computer Science 2024-11-12 Thang Nguyen , Dung Nguyen , Kha Pham , Truyen Tran

The COVID-19 pandemic has highlighted the need for quantitative modeling and analysis to understand real-world disease dynamics. In particular, post hoc analyses using compartmental models offer valuable insights into the effectiveness of…

Machine Learning · Computer Science 2025-10-09 Phillip Rothenbeck , Sai Karthikeya Vemuri , Niklas Penzel , Joachim Denzler

Accurate forecasting of contagious diseases is critical for public health policymaking and pandemic preparedness. We propose a new infectious disease forecasting model based on physics-informed neural networks (PINNs), an emerging…

Machine Learning · Computer Science 2025-04-30 Ying Qian , Kui Zhang , Éric Marty , Avranil Basu , Eamon B. O'Dea , Xianqiao Wang , Spencer Fox , Pejman Rohani , John M. Drake , He Li

When investigating epidemic dynamics through differential models, the parameters needed to understand the phenomenon and to simulate forecast scenarios require a delicate calibration phase, often made even more challenging by the scarcity…

Numerical Analysis · Mathematics 2023-09-11 Giulia Bertaglia , Chuan Lu , Lorenzo Pareschi , Xueyu Zhu

This work focuses on understanding the minimum eradication time for the controlled Susceptible-Infectious-Recovered (SIR) model in the time-homogeneous setting, where the infection and recovery rates are constant. The eradication time is…

Optimization and Control · Mathematics 2026-01-27 Minseok Kim , Yeongjong Kim , Yeoneung Kim

We develop a physics-informed neural network (PINN) framework for parameter estimation in fractional-order SEIRD epidemic models. By embedding the Caputo fractional derivative into the network residuals via the L1 discretization scheme, our…

Machine Learning · Statistics 2025-09-30 Achraf Zinihi

Physics-informed neural networks (PINNs) provide a powerful framework for learning governing equations of dynamical systems from data. Biologically-informed neural networks (BINNs) are a variant of PINNs that preserve the known differential…

Machine Learning · Computer Science 2026-04-21 William Lavery , Jodie A. Cochrane , Christian Olesen , Dagim S. Tadele , John T. Nardini , Sara Hamis

There has been an increasing interest in integrating physics knowledge and machine learning for modeling dynamical systems. However, very limited studies have been conducted on seismic wave modeling tasks. A critical challenge is that these…

Geophysics · Physics 2022-11-03 Pu Ren , Chengping Rao , Su Chen , Jian-Xun Wang , Hao Sun , Yang Liu

The spread of many infectious diseases is modeled using variants of the SIR compartmental model, which is a coupled differential equation. The coefficients of the SIR model determine the spread trajectories of disease, on whose basis…

Machine Learning · Computer Science 2023-03-28 Ritam Majumdar , Shirish Karande , Lovekesh Vig

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

Physics-informed neural networks (PINNs) were recently proposed in [1] as an alternative way to solve partial differential equations (PDEs). A neural network (NN) represents the solution while a PDE-induced NN is coupled to the solution NN,…

Computational Physics · Physics 2019-10-22 Xiaoli Chen , Jinqiao Duan , George Em Karniadakis

We introduce Structure Informed Neural Networks (SINNs), a novel method for solving boundary observation problems involving PDEs. The SINN methodology is a data-driven framework for creating approximate solutions to internal variables on…

Fluid Dynamics · Physics 2023-10-31 Jakub Horsky , Andrew Wynn

Data-driven deep learning provides efficient algorithms for parameter identification of epidemiology models. Unlike the constant parameters, the complexity of identifying time-varying parameters is largely increased. In this paper, a…

Dynamical Systems · Mathematics 2021-03-19 Jie Long , Abdul Khaliq , Khaled Furati

A variety of approaches using compartmental models have been used to study the COVID-19 pandemic and the usage of machine learning methods with these models has had particularly notable success. We present here an approach toward analyzing…

Populations and Evolution · Quantitative Biology 2022-08-19 Haoran Hu , Connor M Kennedy , Panayotis G. Kevrekidis , Hongkun Zhang

Physics-Informed Neural Networks (PINNs) frequently encounter difficulties in accurately resolving shock waves within high-speed compressible flows, a failure largely attributed to the "gradient pathology" arising from extreme stiffness at…

Computational Physics · Physics 2026-05-25 Darui Zhao , Ze Tao , Fujun Liu

Estimating the material distribution of Earth's subsurface is a challenging task in seismology and earthquake engineering. The recent development of physics-informed neural network (PINN) has shed new light on seismic inversion. In this…

Geophysics · Physics 2023-05-10 Pu Ren , Chengping Rao , Hao Sun , Yang Liu
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