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Risk scores are simple classification models that let users make quick risk predictions by adding and subtracting a few small numbers. These models are widely used in medicine and criminal justice, but are difficult to learn from data…

Machine Learning · Statistics 2020-10-21 Berk Ustun , Cynthia Rudin

Risk scoring systems are widely used in high-stakes domains to assist decision-making. However, existing approaches often focus on optimizing predictive accuracy or likelihood-based criteria, which may not align with the main goal of…

Machine Learning · Computer Science 2026-04-07 Wenhao Chi , Ş. İlker Birbil

Over the last century, risk scores have been the most popular form of predictive model used in healthcare and criminal justice. Risk scores are sparse linear models with integer coefficients; often these models can be memorized or placed on…

Machine Learning · Computer Science 2022-10-13 Jiachang Liu , Chudi Zhong , Boxuan Li , Margo Seltzer , Cynthia Rudin

Risk scores are an interpretable and actionable class of machine learning models with applications in medicine, insurance, and risk management. Unlike most computational methods, risk scores are designed to be computed by a human by…

Machine Learning · Computer Science 2026-05-05 Costa Georgantas , Jonas Richiardi

Machine learning systems show significant promise for forecasting patient adverse events via risk scores. However, these risk scores implicitly encode assumptions about future interventions that the patient is likely to receive, based on…

In this paper, we propose a novel Mixed-Integer Non-Linear Optimization formulation to construct a risk score, where we optimize the logistic loss with sparsity constraints. Previous approaches are typically designed to handle binary…

Optimization and Control · Mathematics 2025-02-13 Cristina Molero-Río , Claudia D'Ambrosio

We intend to create a new risk assessment methodology that combines the best characteristics of both risk score and machine learning models. More specifically, we aim to develop a method that, besides having a good performance, offers a…

Machine Learning · Computer Science 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

Many in-hospital mortality risk prediction scores dichotomize predictive variables to simplify the score calculation. However, hard thresholding in these additive stepwise scores of the form "add x points if variable v is above/below…

Machine Learning · Statistics 2015-04-30 Natalia M. Arzeno , Karla A. Lawson , Sarah V. Duzinski , Haris Vikalo

Many diagnostic errors occur because clinicians cannot easily access relevant information in patient Electronic Health Records (EHRs). In this work we propose a method to use LLMs to identify pieces of evidence in patient EHR data that…

We propose a nonparametric additive model for estimating interpretable value functions in reinforcement learning, with an application in optimizing postoperative recovery through personalized, adaptive recommendations. While reinforcement…

Machine Learning · Statistics 2025-06-02 Patrick Emedom-Nnamdi , Timothy R. Smith , Jukka-Pekka Onnela , Junwei Lu

Motivated by modern applications such as computerized adaptive testing, sequential rank aggregation, and heterogeneous data source selection, we study the problem of active sequential estimation, which involves adaptively selecting…

Statistics Theory · Mathematics 2024-02-14 Xiaoou Li , Hongru Zhao

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

The study of a machine learning problem is in many ways is difficult to separate from the study of the loss function being used. One avenue of inquiry has been to look at these loss functions in terms of their properties as scoring rules…

Machine Learning · Computer Science 2022-09-02 Zac Cranko , Robert C. Williamson , Richard Nock

Medical decision-making makes frequent use of algorithms that combine risk equations with rules, providing clear and standardized treatment pathways. Symbolic regression (SR) traditionally limits its search space to continuous function…

Scoring systems are linear classification models that only require users to add or subtract a few small numbers in order to make a prediction. They are used for example by clinicians to assess the risk of medical conditions. This work…

Human-Computer Interaction · Computer Science 2019-12-02 Hans-Jürgen Profitlich , Daniel Sonntag

Risk assessment tools in healthcare commonly employ point-based scoring systems that map patients to ordinal risk categories via thresholds. While electronic health record (EHR) data presents opportunities for data-driven optimization of…

Machine Learning · Computer Science 2026-04-20 Fardin Ganjkhanloo , Emmett Springer , Erik H. Hoyer , Daniel L. Young , Kimia Ghobadi

Prediction of mortality in intensive care unit (ICU) patients typically relies on black box models (that are unacceptable for use in hospitals) or hand-tuned interpretable models (that might lead to the loss in performance). We aim to…

Machine Learning · Computer Science 2025-01-09 Chloe Qinyu Zhu , Muhang Tian , Lesia Semenova , Jiachang Liu , Jack Xu , Joseph Scarpa , Cynthia Rudin

Predicting the risk of in-hospital mortality from electronic health records (EHRs) has received considerable attention. Such predictions will provide early warning of a patient's health condition to healthcare professionals so that timely…

Machine Learning · Computer Science 2023-08-22 Yuxi Liu , Zhenhao Zhang , Shaowen Qin , Flora D. Salim , Antonio Jimeno Yepes

Inherent risk scoring is an important function in anti-money laundering, used for determining the riskiness of an individual during onboarding $\textit{before}$ fraudulent transactions occur. It is, however, often fraught with two…

Machine Learning · Computer Science 2018-12-02 W. Ronny Huang , Miguel A. Perez

In healthcare, the highest risk individuals for morbidity and mortality are rarely those with the greatest modifiable risk. By contrast, many machine learning formulations implicitly attend to the highest risk individuals. We focus on this…

Machine Learning · Statistics 2019-11-15 Yoonjung Kim , Jeremy C. Weiss
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