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Guided by extensive numerical simulations, we propose a microfluidic device that can sort elastic capsules by their deformability. The device consists of a duct embedded with a semi-cylindrical obstacle, and a diffuser which further…

Fluid Dynamics · Physics 2014-09-18 Lailai Zhu , Cecilia Rorai , Dhrubaditya Mitra , Luca Brandt

Long, shallow microchannels embedded in thick soft materials are widely used in microfluidic devices for lab-on-a-chip applications. However, the bulging effect caused by fluid--structure interactions between the internal viscous flow and…

Fluid Dynamics · Physics 2019-12-03 Xiaojia Wang , Ivan C. Christov

Reconstructing the three-dimensional (3D) geometry of object surfaces is essential for robot perception, yet vision-based approaches are generally unreliable under low illumination or occlusion. This limitation motivates the design of a…

Robotics · Computer Science 2026-01-21 Guanyu Xu , Jiaqi Wang , Dezhong Tong , Xiaonan Huang

The ability of detecting and separating CTCs can play a key role in early cancer detection and treatment. In recent years, there has been growing interest in using deformability-based CTC separation microfilters due to their simplicity and…

Cell Behavior · Quantitative Biology 2016-01-11 Mohammad Aghaamoo , Zhifeng Zhang , Xiaolin Chen , Jie Xu

Microcapsules with liquid cores encapsulated by thin membranes have many applications in science, medicine and industry. In this paper, we design a suspension of microcapsules which flow and deform like red blood cells (RBCs), as a valuable…

Soft Condensed Matter · Physics 2023-02-22 Qi Chen , Naval Singh , Kerstin Schirrmann , Qi Zhou , Igor Chernyavsky , Anne Juel

Sorting cells based on their intrinsic properties is a highly desirable objective, since changes in cell deformability are often associated with various stress conditions and diseases. Deterministic lateral displacement (DLD) devices offer…

Fluid Dynamics · Physics 2024-06-03 Zunmin Zhang , Wei Chien , Ewan Henry , Dmitry A. Fedosov , Gerhard Gompper

In this study the possibility of combining commercial Scanning Force Microscopes (SFM) with stretching devices for the investigation of microscopic surface changes during stepwise elongation is investigated. Different types of stretching…

Soft Condensed Matter · Physics 2013-12-11 Sabine Hild , Armin Rosa , Othmar Marti

Adiabatic waveguide taper and on-chip wavelength demultiplexer are the key components of photonic integrated circuits. However, these two kinds of devices which designed by traditional semi-analytic methods or brute-force search methods…

It is widely agreed that phase change materials (PCMs) are of high interest for sustainable energy future. Many of the applications require anti-leakage properties of PCM, that can be accomplished through PCM encapsulation. In this study,…

The shape of a microchannel during flow through it is instrumental to understanding the physics that govern various phenomena ranging from rheological measurements of fluids to separation of particles and cells. Two commonly used approaches…

Multilayer metasurfaces provide substantially greater spectral design freedom than single-layer devices, yet their implementation in the visible and near-infrared remains limited by the complexity, cost, and low throughput of conventional…

Optics · Physics 2026-01-21 A. Bilgehan Baspinar , Phillippe Pearson , Andrei Faraon

We have developed a poly(dimethylsiloxane) (PDMS) microfluidic chip to study the directional drying of a colloidal dispersion confined in a channel. Our measurements on a dispersion of silica nanoparticles once again revealed the…

Soft Condensed Matter · Physics 2024-01-11 Hrishikesh Pingulkar , Sonia Maréchal , Jean-Baptiste Salmon

We present a theoretical model for the evolution of mixture concentrations in a micro-pervaporation device, similar to those recently presented experimentally. The described device makes use of the pervaporation of water through a thin PDMS…

Soft Condensed Matter · Physics 2009-03-30 Michael Schindler , Armand Ajdari

Soft matters whose constituents are deformable are ubiquitous in nature especially in biological systems-including cells and their organelles-as well as in foams and emulsions. The capacity for deformation in these soft materials gives rise…

Soft Condensed Matter · Physics 2026-03-05 Padmanabha Bose , Smarajit Karmakar

Deformable Mirrors (DMs) have wide applications ranging from astronomical imaging to laser communications and vision science. However, they often require bulky multi-channel cables for delivering high power to their drive actuators. A low…

Instrumentation and Methods for Astrophysics · Physics 2021-12-28 Amit Kumar Jha , Ewan S. Douglas , Meng Li , Corey Fucetola , Fiorenzo G. Omenetto

Lack of stiffness often limits thin shape-shifting structures to small scales. The large in-plane transformations required to distort the metrics are indeed commonly achieved by using soft hydrogels or elastomers. We introduce here a…

Soft Condensed Matter · Physics 2020-11-23 Emmanuel Siéfert , Etienne Reyssat , José Bico , Benoît Roman

Shape transformation is crucial for the survival, adaptation, predation, defense, and reproduction of organisms in complex environments. It also serves as a key mechanism for the development of various applications, including soft robotics,…

Applied Physics · Physics 2024-10-17 Xiaoyu Su

Microfluidic chips provide unparalleled control over droplets and jets, which have advanced all natural sciences. However, microfluidic applications could be vastly expanded by increasing the per-channel throughput and directly exploiting…

Metasurfaces (MSs) have been utilized to manipulate different properties of electromagnetic waves. By combining local control over the wave amplitude, phase, and polarization into a single tunable structure, a multi-functional and…

Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently…

Computational Physics · Physics 2020-06-23 Hakan Başağaoğlu , Justin Blount , Sauro Succi , Christopher J. Freitas