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A microfluidic device is constructed from PDMS with a single channel having a short section that is a thin flexible membrane, in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a…

Soft Condensed Matter · Physics 2020-07-03 Debadi Chakraborty , J. Ravi Prakash , Leslie Yeo , James Friend

Accurate pressure measurements in micrometric channels are essential for a wide range of microfluidic applications. Existing approaches rely on a variety of sensing mechanisms, but generally require the integration of additional probes or…

We present a microfluidic device that enables trapping, analysis, and on-demand release of individual microparticles through membrane deformation driven by pneumatic actuation. Inspired by Pachinko-style architectures, the system features…

Applied Physics · Physics 2025-07-10 Alexandre Chargueraud , Lars Kool , Jacques Fattaccioli

The emerging field of deformable microfluidics widely employed in the Lab-on-a-Chip and MEMS communities offers an opportunity to study a relatively under-examined physics. The main objective of this work is to provide a deeper insight into…

Fluid Dynamics · Physics 2018-09-14 Aryan Mehboudi , Junghoon Yeom

Microfluidic channels are integral to biomedical technology and process engineering, offering versatility in handling fluids with complex properties, often a combination of viscous and elastic attributes. Despite significant advancements in…

Soft Condensed Matter · Physics 2025-09-29 Sampad Laha , Siddhartha Mukherjee , Suman Chakraborty

Integrated micro-nanochannel networks in fluidic devices are desirable in a number of applications ranging from self-healing/cooling materials to bioengineering. The conventional micro-manufacturing techniques are capable of either…

Materials Science · Physics 2017-04-10 Prasoon Kumar , Prasanna S Gandhi , Mainak Majumder

Flexible microfluidics have found extensive utility in the biological and biomedical fields. A leading substrate material for compliant devices is polydimethylsiloxane (PDMS). Despite its many advantages, PDMS is inherently hydrophobic and…

In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical…

Deformable microchannels emulate a key characteristic of soft biological systems and flexible engineering devices: the flow-induced deformation of the conduit due to slow viscous flow within. Elucidating the two-way coupling between…

Fluid Dynamics · Physics 2026-01-14 Anxu Huang , Shrihari D. Pande , Jie Feng , Ivan C. Christov

Microfluidic valves play a key role within microfluidic systems by regulating fluid flow through distinct microchannels, enabling many advanced applications in medical diagnostics, lab-on-chips, and laboratory automation. While microfluidic…

Materials Science · Physics 2023-12-19 Tinku Supakar , David Space , Sophy Meija , Rou Yu Tan , Jeffrey R. Alston , Eric A. Josephs

Polydimethylsiloxane (PDMS) microfluidic devices have become a standard tool for engineering cells and multicellular networks in vitro. However, the reservoirs, or through-holes where cells access the devices, are usually fabricated…

Applied Physics · Physics 2020-12-02 Taiki Takemuro , Hideaki Yamamoto , Shigeo Sato , Ayumi Hirano-Iwata

The integration of a PDMS membrane within orthogonally placed PMMA microfluidic channels enables the pneumatic actuation of valves within bonded PMMA-PDMS-PMMA multilayer devices. Here, surface functionalization of PMMA substrates via acid…

Other Computer Science · Computer Science 2008-12-18 A. G. G. Toh , Z. F. Wang , S. H. Ng

Deformation band patterning in single crystals is investigated using a finite strain crystal viscoplasticity model based on the evolution of dislocation densities. In the presence of strong latent hardening and weak rate dependence, the…

Materials Science · Physics 2025-07-02 Jean-Michel Scherer

We have demonstrated the fabrication and characterization of 2D liquid-based multimode optical waveguide structures over a Polydimethylsiloxane (PDMS) material-based chip. Fabrication of two separate microstructures, one with a width of 14…

Optics · Physics 2023-01-27 Sanyogita , Amar Ghar , P. K. Panigrahi

Droplet-based microfluidics systems have become widely used in recent years thanks to their advantages, varying from the possibility of handling small fluid volumes to directly synthesizing and encapsulating various living forms for…

Direct and noninvasive measurement of the pressure distribution in test sections of a micro-channel is a challenging, if not an impossible, task. Here, we present an analytical method for extracting the pressure distribution in a deformable…

Fluid Dynamics · Physics 2013-10-09 O. Ozsun , V. Yakhot , K. L. Ekinci

Encapsulation of chemicals using polymer membranes enables to control their transport and delivery for applications such as agrochemistry or detergency. To rationalize the design of polymer capsules, it is necessary to understand how the…

Soft Condensed Matter · Physics 2018-12-18 Corentin Tregouët , Thomas Salez , Mathilde Reyssat , Cécile Monteux

Large-scale microfluidic microsystems with complex three-dimensional (3D) configurations are highly in demand by both fundamental research and industrial application, holding the potentials for fostering a wide range of innovative…

Applied Physics · Physics 2020-01-13 Zijie Lin , Jian Xu , Yunpeng Song , Xiaolong Li , Peng Wang , Wei Chu , Zhenhua Wang , Ya Cheng

Soft particles suspended in fluids flowing through microchannels are often encountered in biological flows such as cells in vessels. They can deform under flow or when subject to mechanical stresses as they interact with themselves.…

Soft Condensed Matter · Physics 2021-01-19 Danilo P. F. Silva , Rodrigo C. V. Coelho , Margarida M. Telo da Gama , Nuno A. M. Araújo

Inexpensive, portable lab-on-a-chip devices would revolutionize fields like environmental monitoring and global health, but current microfluidic chips are tethered to extensive off-chip hardware. Insects, however, are self-contained and…

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