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Related papers: The Learnability Gap in Medical Latent Diffusion

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Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

Leveraging the powerful capabilities of diffusion models has yielded quite effective results in medical image segmentation tasks. However, existing methods typically transfer the original training process directly without specific…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Qilin Huang , Tianyu Lin , Zhiguang Chen , Fudan Zheng

Modern Latent Diffusion Models (LDMs) typically operate in low-level Variational Autoencoder (VAE) latent spaces that are primarily optimized for pixel-level reconstruction. To unify vision generation and understanding, a burgeoning trend…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Shilong Zhang , He Zhang , Zhifei Zhang , Chongjian Ge , Shuchen Xue , Shaoteng Liu , Mengwei Ren , Soo Ye Kim , Yuqian Zhou , Qing Liu , Daniil Pakhomov , Kai Zhang , Zhe Lin , Ping Luo

We explore a framework for protein sequence representation learning that decomposes the task between manifold learning and distributional modelling. Specifically we present a Latent Space Diffusion architecture which combines a protein…

Machine Learning · Computer Science 2025-03-25 Eoin Quinn , Ghassene Jebali , Maxime Seince , Oliver Bent

Generative models have demonstrated strong performance in conditional settings and can be viewed as a form of data compression, where the condition serves as a compact representation. However, their limited controllability and…

Machine Learning · Computer Science 2025-07-04 Xiao Li , Liangji Zhu , Anand Rangarajan , Sanjay Ranka

Recent generative-prior-based methods have shown promising blind face restoration performance. They usually project the degraded images to the latent space and then decode high-quality faces either by single-stage latent optimization or…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Maitreya Suin , Rama Chellappa

Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Houze Liu , Tong Zhou , Yanlin Xiang , Aoran Shen , Jiacheng Hu , Junliang Du

Recent advances in latent diffusion models have demonstrated their effectiveness for high-resolution image synthesis. However, the properties of the latent space from tokenizer for better learning and generation of diffusion models remain…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Hao Chen , Yujin Han , Fangyi Chen , Xiang Li , Yidong Wang , Jindong Wang , Ze Wang , Zicheng Liu , Difan Zou , Bhiksha Raj

Once deployed, medical image analysis methods are often faced with unexpected image corruptions and noise perturbations. These unknown covariate shifts present significant challenges to deep learning based methods trained on "clean" images.…

Machine Learning · Computer Science 2025-07-01 Xing Shen , Hengguan Huang , Brennan Nichyporuk , Tal Arbel

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Obtaining pixel-level annotations in the medical domain is both expensive and time-consuming, often requiring close collaboration between clinical experts and developers. Semi-supervised medical image segmentation aims to leverage limited…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Lin Xi , Yingliang Ma , Cheng Wang , Sandra Howell , Aldo Rinaldi , Kawal S. Rhode

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

Although deep learning models in medical imaging often achieve excellent classification performance, they can rely on shortcut learning, exploiting spurious correlations or confounding factors that are not causally related to the target…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Sarah Müller , Philipp Berens

Deep learning based medical image recognition systems often require a substantial amount of training data with expert annotations, which can be expensive and time-consuming to obtain. Recently, synthetic augmentation techniques have been…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Jiarong Ye , Haomiao Ni , Peng Jin , Sharon X. Huang , Yuan Xue

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Deep learning has revolutionized medical image analysis, playing a vital role in modern clinical applications. However, the deployment of large-scale models in real-world clinical settings remains challenging due to high computational…

Machine Learning · Computer Science 2026-02-03 Cuong Manh Nguyen , Truong-Son Hy

Latent variable generative models have emerged as powerful tools for generative tasks including image and video synthesis. These models are enabled by pretrained autoencoders that map high resolution data into a compressed lower dimensional…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Mohammed Suhail , Carlos Esteves , Leonid Sigal , Ameesh Makadia

Continual learning protocols are attracting increasing attention from the medical imaging community. In continual environments, datasets acquired under different conditions arrive sequentially; and each is only available for a limited…

Computer Vision and Pattern Recognition · Computer Science 2023-02-13 Camila Gonzalez , Nick Lemke , Georgios Sakas , Anirban Mukhopadhyay

The recovery of training data from generative models ("model inversion") has been extensively studied for diffusion models in the data domain as a memorization/overfitting phenomenon. Latent diffusion models (LDMs), which operate on the…

Machine Learning · Computer Science 2026-03-26 Mingxing Rao , Bowen Qu , Daniel Moyer